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Nflox-B 400 mg Tablet is an antibiotic used to treat various bacterial infections in different parts of the body. Betadex (Beta-cyclodextrin), a carrier molecule, enhances the absorption and effectiveness of Norfloxacin. Norfloxacin works by either killing bacteria or inhibiting their growth. Common side effects may include abdominal cramps, nausea, headache, diarrhea, and dizziness. If you are pregnant or breastfeeding, consult your doctor before using Nflox-B 400 mg Tablet .

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Synonym :

BETA CYCLODEXTRAN+NORFLOXACIN

Manufacturer/Marketer :

Laborate Pharmaceuticals India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Nflox-B 400 mg Tablet

Nflox-B 400 mg Tablet is a combination medication used to treat bacterial infections, including urinary tract infections, prostatitis (inflammation of the prostate), and gonorrhea (a sexually transmitted infection). A bacterial infection occurs when harmful bacteria enter the body, multiply, and cause harm to tissues or organs, leading to symptoms like pain, fever, and inflammation.

Nflox-B 400 mg Tablet  contains Betadex (Beta-Cyclodextrin) and Norfloxacin. Beta-cyclodextrin increases the effectiveness of norfloxacin by improving its solubility, allowing it to be absorbed more quickly into the bloodstream and reach adequate levels in the body. Norfloxacin is a fluoroquinolone antibiotic that kills bacteria by inhibiting DNA synthesis.

Take Nflox-B 400 mg Tablet for the duration your doctor prescribes, based on your medical condition. Some common side effects may include abdominal cramps, nausea, headache, diarrhea, and dizziness. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.

Inform your doctor before using Nflox-B 400 mg Tablet if you have a history of heart, liver, or kidney disease. Avoid taking this medication during pregnancy or breastfeeding unless prescribed by your doctor. Keep your doctor updated on your medications and health condition to prevent potential side effects.

Uses of Nflox-B 400 mg Tablet

Nflox-B 400 mg Tablet is used in the treatment of bacterial infections.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nflox-B 400 mg Tablet belongs to a group of medicines called quinolone antibiotics, used to treat bacterial infections, including urinary tract infections, prostatitis, and gonorrhea. It is a combination of beta-cyclodextrin and norfloxacin. Beta-cyclodextrin enhances the effectiveness of Norfloxacin. Norfloxacin is a fluoroquinolone antibiotic that kills bacteria by inhibiting DNA synthesis. Together, they provide a potent treatment for many bacterial infections, ensuring better absorption and increased antibacterial action.

How Nflox-B 400 mg Tablet Works

Nflox-B 400 mg Tablet includes Beta-Cyclodextrin and Norfloxacin. The presence of beta-cyclodextrin improves the potency of norfloxacin. Norfloxacin works by blocking the production of the DNA gyrase enzyme, which leads to bacterial death and helps treat infections. Nflox-B 400 mg Tablet exhibits a wide range of antibacterial effects against both gram-positive and gram-negative aerobic bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nflox-B 400 mg Tablet

  • Nausea
  • Headache
  • Diarrhea
  • Dizziness
  • Abdominal pain

What if I have taken an overdose of Nflox-B 400 mg Tablet

Take Nflox-B 400 mg Tablet only as advised by the physician. Do not exceed the prescribed dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Nflox-B 400 mg Tablet if you are allergic to any of its ingredients or if you have experienced tendon swelling or rupture while using quinolone antibiotics. Seek medical attention immediately if you experience pain, swelling, or inflammation in your tendons while using Nflox-B 400 mg Tablet . Inform your doctor if you have epilepsy, low potassium levels, muscle or nerve disorders, a head injury or brain tumor, diabetes, rheumatoid arthritis, or heart, kidney, or liver conditions. Discuss with your doctor if you are pregnant or breastfeeding. Limit alcohol intake while using Nflox-B 400 mg Tablet , as it may increase dizziness. Nflox-B 400 mg Tablet can cause dizziness and vision disturbances, so exercise caution when driving or operating machinery.

 

Drug-Drug Interactions

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NorfloxacinCisapride
Critical
NorfloxacinAmiodarone
Critical

Drug-Drug Interactions

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NorfloxacinCisapride
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
The combination of Amiodarone and Nflox-B 400 mg Tablet 10's may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Nflox-B 400 mg Tablet 10's interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinSotalol
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Using bepridil together with Nflox-B 400 mg Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Using Mesoridazine together with Nflox-B 400 mg Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Nflox-B 400 mg Tablet 10's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinEfavirenz
Severe
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Efavirenz can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorfloxacinIohexol
Severe
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Iohexol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Iohexol together can result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not discontinue any medications without consulting a doctor.
NorfloxacinRibociclib
Severe
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Using Ribociclib together with Nflox-B 400 mg Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Ribociclib together can result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a slow heart rate, irregular heart rhythm, dizziness, fainting, or trouble breathing, you should call your doctor right away. Do not stop using any medications without talking to a doctor.
NorfloxacinVandetanib
Severe
How does the drug interact with Nflox-B 400 mg Tablet 10's:
Coadministration of Nflox-B 400 mg Tablet 10's with Vandetanib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet 10's with Vandetanib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MG+BETADEX-10MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MG+BETADEX-10MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Nflox-B 400 mg Tablet 10's can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Nflox-B 400 mg Tablet 10's may increase the effects of caffeine. Nflox-B 400 mg Tablet 10's dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Nflox-B 400 mg Tablet 10's. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Drink plenty of water to stay hydrated.
  • Consume a well-balanced diet that includes fruits, vegetables, whole grains, and lean protein.
  • Engage in mild physical activity rather than intense exercise.
  • Limit dairy products (milk, cheese, yogurt) as they can interfere with absorption.
  • Avoid alcohol to reduce the risk of side effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid consumption of alcohol with Nflox-B 400 mg Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Nflox-B 400 mg Tablet .

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

There is limited information on how Nflox-B 400 mg Tablet affects breastfeeding. Please consult your doctor before taking Nflox-B 400 mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Nflox-B 400 mg Tablet may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Nflox-B 400 mg Tablet .

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Liver

Consult your doctor

Consult your doctor before taking Nflox-B 400 mg Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Consult your doctor before taking Nflox-B 400 mg Tablet if you have a kidney problem or any concerns regarding this.

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Children

Consult your doctor

Nflox-B 400 mg Tablet should not be given to children as safety and effectiveness were not established. Please consult your doctor before giving Nflox-B 400 mg Tablet to your child.

FAQs

Nflox-B 400 mg Tablet is used to treat bacterial infections, including urinary tract infections, prostatitis (inflammation of the prostate), and gonorrhea (a sexually transmitted infection).
Nflox-B 400 mg Tablet is a combination of Betadex (Beta-Cyclodextrin) and Norfloxacin. The presence of beta-cyclodextrin improves the potency of norfloxacin. Norfloxacin works by blocking the production of the DNA gyrase enzyme, which leads to bacterial death and helps treat infections.
No, avoid dairy products, calcium-rich foods, and antacids, as they can reduce the effectiveness of norfloxacin.
If your condition does not improve after completing the full course of Nflox-B 400 mg Tablet inform your doctor. Also, notify them if your symptoms worsen during treatment. Your doctor may examine your condition, recommend further tests, or adjust your treatment if needed.
The duration of treatment varies according to the type of infection. Follow your doctor’s instructions and finish the full course to prevent the infection from coming back or becoming resistant.
Common side effects include abdominal cramps, nausea, headache, diarrhea, and dizziness. These side effects are generally mild and typically go away on their own over time. However, if they persist or become worse, consult your doctor for further guidance.

Country of origin

India

Manufacturer/Marketer address

E-11, Industrial Area, Panipat, Haryana-132103
Other Info - NFL0006

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