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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mysoline 250 Tablet is used to control seizures. It contains Primidone which works by decreasing abnormal electrical activity in the brain. In some cases, this medicine may cause side effects such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, and impaired coordination. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

PRIMIDONE-250MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mysoline 250 Tablet

Mysoline 250 Tablet is used to control various epileptic conditions (fits), prevent seizures and treat shaking attacks (essential tremors). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain, leading to seizures, unusual behaviour, and loss of awareness. Mysoline 250 Tablet is ineffective for treating absence (petit mal) seizures.

Mysoline 250 Tablet contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Mysoline 250 Tablet prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only. 

Take Mysoline 250 Tablet with or without food. You are advised to take Mysoline 250 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, impaired coordination, and nystagmus (involuntary eye movement). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition, effectually continue taking Mysoline 250 Tablet for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Mysoline 250 Tablet suddenly without consulting your doctor, as it may lead to increased seizures. Avoid taking Mysoline 250 Tablet if you are pregnant or breastfeeding unless prescribed. Mysoline 250 Tablet should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Mysoline 250 Tablet as it might increase side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Mysoline 250 Tablet

Mysoline 250 Tablet is used to treat Epilepsy (fits), Bipolar disorder, and Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Syrup: Take the prescribed dose by mouth using the measuring cup/dosing syringe. Shake the bottle well before use.

Medicinal Benefits

Mysoline 250 Tablet belongs to the group of anticonvulsant medicines. It contains Primidone, which is used to control epilepsy (fits). Mysoline 250 Tablet is also used to control and prevent fits during or after a severe head injury or brain surgery. Mysoline 250 Tablet is also used to treat trigeminal neuralgia (facial nerve pain). Mysoline 250 Tablet works by controlling the overactivity of the brain that causes seizures (fits). Thereby, Mysoline 250 Tablet helps in controlling epileptic fits involving muscle spasms and jerking.

How Mysoline 250 Tablet Works

Mysoline 250 Tablet contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Mysoline 250 Tablet prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mysoline 250 Tablet

  • Headache
  • Nausea
  • Dizziness
  • Drowsiness
  • Low energy
  • Vomiting
  • Vertigo
  • Visual impairment
  • Impaired coordination
  • Nystagmus (involuntary eye movement)

What if I have taken an overdose of Mysoline 250 Tablet

Take Mysoline 250 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose of Mysoline 250 Tablet may cause ataxia (loss of muscle control), loss of consciousness, respiratory depression and coma. Seek immediate medical attention if you have taken an overdose.

Drug Warnings

Do not take Mysoline 250 Tablet if you are allergic to any of its contents. Do not skip doses or stop taking Mysoline 250 Tablet suddenly without consulting your doctor, as Mysoline 250 Tablet may cause increased seizures. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Mysoline 250 Tablet if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Mysoline 250 Tablet as it might cause unpleasant side effects. Mysoline 250 Tablet should not be used by children unless prescribed. Let your doctor know if you have diabetes, as intake of Mysoline 250 Tablet affects the blood sugar level. Intake of Mysoline 250 Tablet may cause dizziness, so be cautious while driving or operating heavy machinery.

Drug-Drug Interactions

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PrimidoneRanolazine
Critical
PrimidoneBoceprevir
Critical

Drug-Drug Interactions

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PrimidoneRanolazine
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Coadministration of ranolazine with Mysoline 250 Tablet 10's can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between Mysoline 250 Tablet 10's and Ranolazine, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneBoceprevir
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Coadministration of boceprevir with Mysoline 250 Tablet 10's may decrease the blood levels of boceprevir, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Mysoline 250 Tablet 10's and boceprevir, they can be taken together if your doctor advises. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidonePirfenidone
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Coadministration of pirfenidone with Mysoline 250 Tablet 10's can reduce levels and the effects of pirfenidone.

How to manage the interaction:
Although there is an interaction between pirfenidone and Mysoline 250 Tablet 10's, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidonePraziquantel
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Taking praziquantel with Mysoline 250 Tablet 10's can lower the levels of praziquantel in your blood, which leads to a decreased therapeutic effect.

How to manage the interaction:
Taking Mysoline 250 Tablet 10's with Praziquantel is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneRitonavir
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Taking ritonavir and Mysoline 250 Tablet 10's may decrease the blood levels of ritonavir.

How to manage the interaction:
Taking Mysoline 250 Tablet 10's with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneVoriconazole
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Taking voriconazole together with Mysoline 250 Tablet 10's may reduce the blood levels of voriconazole, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Voriconazole and Mysoline 250 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrimidoneIsavuconazole
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Taking isavuconazole with Mysoline 250 Tablet 10's may decrease the blood levels of isavuconazole and reduce its effectiveness.

How to manage the interaction:
Taking isavuconazole with Mysoline 250 Tablet 10's is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneDaclatasvir
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Coadministration of daclatasvir with Mysoline 250 Tablet 10's may decrease the blood levels of daclatasvir, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Mysoline 250 Tablet 10's and Daclatasvir, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneLurasidone
Critical
How does the drug interact with Mysoline 250 Tablet 10's:
Co-administration of lurasidone with Mysoline 250 Tablet 10's may result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Lurasidone and Mysoline 250 Tablet 10's, so it is not recommended; it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneDasatinib
Severe
How does the drug interact with Mysoline 250 Tablet 10's:
Taking Dasatinib with Mysoline 250 Tablet 10's may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between Mysoline 250 Tablet 10's and Dasatinib, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, participating in a task, and smelling a strong odour are a few self-control methods for preventing seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly. Avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Mysoline 250 Tablet to prevent unpleasant side effects.

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Pregnancy

Caution

Do not take Mysoline 250 Tablet if you are pregnant unless prescribed by the doctor. If you become pregnant while taking Mysoline 250 Tablet , then do not stop taking Mysoline 250 Tablet without consulting your doctor. Your doctor will prescribe Mysoline 250 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Mysoline 250 Tablet can be given to breastfeeding mothers.

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Driving

Caution

Mysoline 250 Tablet may cause dizziness and drowsiness, drive and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Mysoline 250 Tablet can be given to children if prescribed by the doctor.

FAQs

Mysoline 250 Tablet is used for the treatment of Epilepsy (fits), Bipolar disorder, and Migraine.
Mysoline 250 Tablet works by controlling overactivity of the brain that causes seizures (fits). Thereby, Mysoline 250 Tablet helps in controlling epileptic fits involving spasms of the muscles and jerking.
Mysoline 250 Tablet can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Please do not stop taking Mysoline 250 Tablet without consulting your doctor as it may cause increased seizures. Continue taking Mysoline 250 Tablet for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Mysoline 250 Tablet .
Yes, Mysoline 250 Tablet may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.
You should not take Mysoline 250 Tablet if you have liver disease, kidney disease, porphyria (an inherited disease that affects haemoglobin biosynthesis), alcohol dependence and suicidal thoughts.
Primidone may affect the breakdown of blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. This is important if you have diabetes. So, contact a doctor before using Mysoline 250 Tablet in this condition.
A partial seizure, also known as a focal seizure, occurs when there is abnormal electrical activity in just one part of the brain. These seizures can cause a variety of symptoms depending on the area of the brain affected.
It is essential to inform your doctor if are allergic to Mysoline 250 Tablet , if you are taking vitamins, supplements, herbal products and other medicines. Let your know doctor if you have or have ever had porphyria (condition in which certain natural substances accumulate in the body and may cause changes in thinking and behaviour, stomach pain, or other symptoms). It is crucial to inform your doctor if you are pregnant or planning to become pregnant.
No, Mysoline 250 Tablet is not habit forming. However, with the long-term use, Mysoline 250 Tablet can be habit forming. So it's important to take it exactly as prescribed by your doctor. If you have any concerns regarding this, please discuss with your doctor.
If Mysoline 250 Tablet makes you feel sleepy, avoid driving or operating heavy machinery. Avoid taking Mysoline 250 Tablet if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Mysoline 250 Tablet as it may cause unpleasant side effects.
The serious side effects of Mysoline 250 Tablet are painful joints, yellowing of the skin and/or eyes, fever, bleeding or bruising under the skin, suicidal thoughts or behaviour, unusual changes in moods, worsening of depression and swelling of the face, lips, tongue or throat. To check for these side effects, it's important to, monitor for symptoms, and inform your doctor immediately if you notice any of these symptoms.
Yes, Mysoline 250 Tablet can cause headache as a mild and temporary side effect. However, if you experience persistent or severe headaches, please consult your doctor.
No, Mysoline 250 Tablet does not have any effect on blood pressure. However consult your doctor, if you notice any changes in the blood pressure.
You are recommended to consult your doctor before taking Mysoline 250 Tablet with propranolol or any other medicines to avoid possible interactions.
Store Mysoline 250 Tablet at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - MYS0002

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