Myo-MR Plus Tablet belongs to the class of medicine called 'muscle relaxant' in combination with a painkiller, used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

Myo-MR Plus Tablet is a combination of two drugs: Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Myo-MR Plus Tablet include nausea, vomiting, dry mouth, dizziness, weakness, and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting Myo-MR Plus Tablet . Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking Myo-MR Plus Tablet if you are pregnant or planning for pregnancy. Myo-MR Plus Tablet may cause dizziness, so drive only if you are alert and focused. Myo-MR Plus Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and Myo-MR Plus Tablet as it could lead to increased dizziness and risk of liver damage.

Myo-MR Plus Tablet treats muscle spasms and consists of Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

• Nausea
• Vomiting
• Dry mouth
• Dizziness
• Weakness
• Sleepiness

Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting Myo-MR Plus Tablet . Consult your doctor before taking Myo-MR Plus Tablet if you are pregnant, planning for pregnancy, or breastfeeding. Myo-MR Plus Tablet may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Myo-MR Plus Tablet as it could lead to increased dizziness and risk of liver damage. Myo-MR Plus Tablet is not recommended in children as safety and efficacy is not established.

Drug-Drug Interaction: Myo-MR Plus Tablet may interact with anticoagulants (warfarin), drugs treating vomiting (metoclopramide, domperidone), cholesterol-lowering medications (cholestyramine) and anti-cancer medications (imatinib).

Drug-Food Interaction: Alcohol consumption may cause dizziness and increases the risk of liver damage.

Drug-Disease Interaction: Before using Myo-MR Plus Tablet , let your doctor know if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency.

• WARFARIN
• METOCLOPRAMIDE
• DOMPERIDONE
• CHOLESTYRAMINE
• IMATINIB

• Exercise regularly as it helps in muscle stretching and makes muscles less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Massages can also be helpful.
• Avoid freezing and hot temperatures.
• Avoid wearing tight-fitting clothes, instead, wear loose garments.
• Rest well and get plenty of sleep.
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.
• Stay hydrated, drink plenty of water.

• Let your doctor know that you are taking Myo-MR Plus Tablet if you are undergoing any medical tests.
• Myo-MR Plus Tablet may cause fluid retention (edema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
• Explain a detail history to the doctor as use of Myo-MR Plus Tablet is contraindicated in patients with myasthenia gravis.

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.