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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 11, 2024 | 2:34 PM IST
Mycograft 180 Tablet is used to prevent organ transplant rejection. It contains Mycophenolate sodium which works by weakening the immune system and preventing it from rejecting the transplanted organ. In some cases, this medicine may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Medgenix Pharma India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Mycograft 180 Tablet

Mycograft 180 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

Mycograft 180 Tablet contains ‘Mycophenolate sodium’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (white blood cells that attack foreign cells) and suppresses antibodies' production (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Take Mycograft 180 Tablet as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Mycograft 180 Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Mycograft 180 Tablet if you are pregnant or planning for pregnancy. Mycograft 180 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Mycograft 180 Tablet should not be given to children as safety and efficacy have not been established. Mycograft 180 Tablet may make you more susceptible to infections, so consult your doctor if you develop fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mycograft 180 Tablet . Do not contact anyone who has shingles, chickenpox, or measles. Do not take Mycograft 180 Tablet if you are not using effective contraception.

Uses of Mycograft 180 Tablet

Treatment of Prevent Organ Transplant Rejection.

Medicinal Benefits

Mycograft 180 Tablet contains ‘Mycophenolate sodium’, which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reactions) in the body.

Directions for Use

Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mycograft 180 Tablet

  • Dizziness

  • Headache

  • Cough

  • Respiratory infections

  • Weakness (asthenia)

  • Muscle pain (myalgia)

  • Shortness of breath (dyspnoea)

Drug Warnings

Do not take Mycograft 180 Tablet if you are allergic to any immunosuppressant medicines or mycophenolate sodium. Let your doctor know before using Mycograft 180 Tablet if you have liver or kidney problems, severe digestive issues, cancer, liver disease (such as hepatitis B, hepatitis C), current/past infections, rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes). Do not take Mycograft 180 Tablet if you are pregnant or planning for pregnancy as Mycograft 180 Tablet is a Pregnancy category risk D medicine which can cause serious congenital disabilities to the unborn baby. Mycograft 180 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Pregnant women should use reliable forms of birth control while on treatment and for six weeks after stopping treatment with Mycograft 180 Tablet . While taking Mycograft 180 Tablet , do not contact anyone who has shingles, chickenpox, or measles. Mycograft 180 Tablet causes dizziness and drowsiness, so drive with caution. Mycograft 180 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Mycograft 180 Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mycograft 180 Tablet .

Drug Interactions

Drug-Drug Interactions: Mycograft 180 Tablet may have interaction with other immunosuppressant medicines (tacrolimus), medicines used to treat high blood cholesterol levels (cholestyramine), activated charcoal used to treat digestive problems, antacids containing magnesium and aluminium and medicines used to treat viral infections (aciclovir or ganciclovir).

Drug-Food Interactions:  Avoid alcohol consumption while taking Mycograft 180 Tablet as it may increase dizziness.

Drug-Disease Interactions: Mycograft 180 Tablet may cause interactions with disease conditions such as cancer, liver disease (such as hepatitis B, hepatitis C), current/past infections, serious digestive problems, rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes).

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • CHOLESTYRAMINE
  • ACTIVATED CHARCOAL
  • ACICLOVIR
  • GANCICLOVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

Special Advise

  • Use sunscreen while taking Mycograft 180 Tablet , as it can make your skin more sensitive to sunlight and may cause skin cancer.

  • Do not donate blood while using this medication and for 6 weeks after stopping it. Do not donate sperm while using this medication and for 90 days after stopping it.

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted into your body, your body recognizes it as a foreign element and tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs are given to such patients to suppress the immune system, stopping it from attacking the newly transplanted organs. Warnings signs of rejection are flu-like symptoms such as chills, headache, nausea, or vomiting, fever higher than 100oF, newly found pain at the region of the transplanted organ, weight gain and fatigue.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Mycograft 180 Tablet . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Mycograft 180 Tablet may cause birth defects and miscarriage if taken during pregnancy. Follow contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mycograft 180 Tablet .

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Breast Feeding

Unsafe

It is not recommended to take Mycograft 180 Tablet while you are breastfeeding. Mycograft 180 Tablet passes into breast milk.

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Driving

Caution

Mycograft 180 Tablet may cause dizziness, tiredness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Take Mycograft 180 Tablet only after the doctor's prescription, especially if you have liver diseases/conditions as your doctor may adjust the dose as required.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Mycograft 180 Tablet as your doctor may adjust the dose as required.

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Children

Unsafe

Mycograft 180 Tablet should not be used by children below 18 years of age, as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

H.No:1-8-32/47, 1St Floor Bapu Bagh, Pg Road, Secunderabad Hyderabad Hyderabad Tg 500003 In
Other Info - MYC0161

Author Details

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FAQs

Mycograft 180 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver.
Mycograft 180 Tablet belongs to the group of medications called ‘immunosuppressants’. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.
Mycograft 180 Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Diarrhoea might be a side-effect of Mycograft 180 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Mycograft 180 Tablet can suppress the immune system and can increase the risk of skin cancer. So, it would be best if you avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).
Mycograft 180 Tablet can suppress the immune system. You should not donate blood while using Mycograft 180 Tablet and at least 60 days after stopping treatment as it makes you more prone to infections. Besides, men should not donate sperm while using Mycograft 180 Tablet for at least 90 days after stopping the treatment.
Some medicines might absorb mycophenolate sodium delayed or absorbed fast if taken concomitantly such as antacids containing aluminium or magnesium, colestipol, cholestyramine or calcium-free phosphate binders. Before taking Mycograft 180 Tablet , speak with your doctor about your ongoing medication list. Your doctor will decide whether they should be taken along with Mycograft 180 Tablet or not.
The live vaccine may not work while on treatment with Mycograft 180 Tablet . Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Mycograft 180 Tablet may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Talk to your doctor if you experience these side effects persistently.
Mycograft 180 Tablet should be swallowed as a whole with water; do not crush or chew it. Mycograft 180 Tablet should be taken on an empty stomach (1 hour before or 2 hours after eating or drinking) or as advised by the doctor.
Avoid prolonged or unnecessary exposure to sunlight (sunlamps, tanning beds) and light therapy and wear protective clothing, sunscreen, and sunglasses. This will help lower your risk of developing skin cancer.
Your doctor has prescribed Mycograft 180 Tablet to suppress the immunity and prevent the rejection of the transplanted kidney.
Mycograft 180 Tablet may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.
Mycograft 180 Tablet is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.
Mycograft 180 Tablet may cause skin problems such as hair loss. Talk to the doctor if you have any concerns.
The doctor may recommend regular blood tests to check for signs of infection and blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.
As Mycograft 180 Tablet reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has asked you to stay away from a person who has chickenpox or shingles.
Mycograft 180 Tablet causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Mycograft 180 Tablet . Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.
As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Mycograft 180 Tablet .

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