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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST

Muciflo 100/600 Tab is used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). It contains Acebrophylline and Acetylcysteine, which works by relaxing muscles and widening the airways of the lungs. Also, it thins and loosens phlegm (mucus) in the lungs, windpipe, and nose. Thus, it helps to cough out easily and makes breathing easier by opening airways. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer

Aristo Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Muciflo 100/600 Tab

Muciflo 100/600 Tab belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner) primarily used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Muciflo 100/600 Tab is a combination of two drugs: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner). Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Muciflo 100/600 Tab breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.

Take Muciflo 100/600 Tab as prescribed. Your doctor will recommend how often you take Muciflo 100/600 Tab based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. Most of these side effects of Muciflo 100/600 Tab do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Muciflo 100/600 Tab or any other medicines, please tell your doctor. Muciflo 100/600 Tab is not recommended for children below 14 years of age. Drink plenty of fluids to thin mucus and lubricate your throat while taking Muciflo 100/600 Tab . Muciflo 100/600 Tab is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Muciflo 100/600 Tab . Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Muciflo 100/600 Tab and contact your doctor immediately. Do not take Muciflo 100/600 Tab if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Muciflo 100/600 Tab if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Muciflo 100/600 Tab .

Uses of Muciflo 100/600 Tab

Treatment of Chronic obstructive pulmonary disease (COPD).

Medicinal Benefits

Muciflo 100/600 Tab is a combination of two drugs: Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Muciflo 100/600 Tab breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.

Directions for Use

Take Muciflo 100/600 Tab with or without food as advised by your doctor. Swallow it whole with a glass of water. Do not break, crush, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Muciflo 100/600 Tab

  • Diarrhoea
  • Stomach pain
  • Nausea
  • Vomiting
  • Runny nose
  • Dizziness
  • Drowsiness
  • Heartburn
  • Skin rash
  • Hives
  • Itching
  • Cool and moist skin

Drug Warnings

If you are allergic to Muciflo 100/600 Tab or any other medicines, please tell your doctor. Muciflo 100/600 Tab is not recommended for children below 14 years of age. Regular monitoring of potassium levels is recommended while taking Muciflo 100/600 Tab as it may cause low potassium levels in the blood. Muciflo 100/600 Tab is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Muciflo 100/600 Tab . Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Muciflo 100/600 Tab and contact your doctor immediately. Do not take Muciflo 100/600 Tab if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Muciflo 100/600 Tab if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Muciflo 100/600 Tab .

Drug Interactions

Drug-Drug Interaction: Muciflo 100/600 Tab may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, tetracycline, gentamicin, amikacin, neomycin), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline), anthelmintic (thiabendazole),  corticosteroids (prednisone), oral contraceptives (ethinylestradiol), medicines used to treat chest pain (glyceryl trinitrate) and cough suppressants (dextromethorphan, codeine).

Drug-Food Interaction: If you are allergic to histamine, avoid histamine-rich foods such as tomatoes, wine, and processed foods. These may cause histamine intolerance, leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching, and rhinitis (runny and stuffy nose). Also, avoid alcohol with Muciflo 100/600 Tab as it may increase drowsiness. Also, avoid or limit the intake of caffeine with Muciflo 100/600 Tab as it may cause side effects.

Drug-Disease Interaction: Avoid taking Muciflo 100/600 Tab if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Muciflo 100/600 Tab .

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AMOXICILLIN
  • DOXYCYCLINE
  • TETRACYCLINE
  • GENTAMICIN
  • AMIKACIN
  • NEOMYCIN
  • DILTIAZEM
  • VERAPAMIL
  • ISOPRENALINE
  • THIABENDAZOLE
  • PREDNISONE
  • ETHINYLESTRADIOL
  • GLYCERYL TRINITRATE
  • DEXTROMETHORPHAN
  • CODEINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in potassium, such as bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots. Potassium is important for lung function, and a potassium deficiency may cause breathing problems.
  • Drink plenty of fluids every day to thin mucus, which makes it easier for coughing out.
  • Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas and potatoes with skin.
  • Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like Red Bull.
  • Eat protein-rich foods such as meat, fish (particularly salmon, sardines and mackerel), eggs and poultry.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Quit smoking as it may reduce the effectiveness of the Muciflo 100/600 Tab and irritate the lungs, worsening breathing problems.

Special Advise

  • Regular blood tests are recommended while taking Muciflo 100/600 Tab to monitor the levels of Muciflo 100/600 Tab and potassium in the blood.
  • Muciflo 100/600 Tab may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Muciflo 100/600 Tab before undergoing any laboratory tests.

Disease/Condition Glossary

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Unsafe

Avoid consumption of alcohol with Muciflo 100/600 Tab as it may reduce the effectiveness of Muciflo 100/600 Tab and increase drowsiness. Please consult a doctor before consuming alcohol with Muciflo 100/600 Tab .

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Pregnancy

Unsafe

Muciflo 100/600 Tab is not recommended for pregnant women. Please consult a doctor before using Muciflo 100/600 Tab if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Muciflo 100/600 Tab is excreted in human milk. Please consult a doctor before taking Muciflo 100/600 Tab if you are breastfeeding.

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Driving

Safe if prescribed

Muciflo 100/600 Tab usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Muciflo 100/600 Tab with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose as required.

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Kidney

Caution

Take Muciflo 100/600 Tab with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Muciflo 100/600 Tab is not recommended for children below 14 years of age. Please consult a doctor before giving Muciflo 100/600 Tab to children.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3Rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai €“ 400 001, India.
Other Info - MUC0245

Author Details

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FAQs

Muciflo 100/600 Tab is used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD), such as shortness of breath, coughing, or wheezing (whistling sound while breathing).
Muciflo 100/600 Tab contains Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Muciflo 100/600 Tab breakdown the acid mucopolysaccharide fibres that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
Muciflo 100/600 Tab should be used with caution in patients suffering from epilepsy (fits) as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Muciflo 100/600 Tab so that the dose may be adjusted or an alternate medicine may be prescribed.
It is not recommended to take Muciflo 100/600 Tab with antibiotics such as tetracycline, amoxicillin, amikacin, and gentamicin at the same time, as this may reduce the effectiveness of the antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of at least 2 hours between taking Muciflo 100/600 Tab and antibiotics. Please consult a doctor before using Muciflo 100/600 Tab with antibiotics or any other medicines.
It is recommended that you avoid taking Muciflo 100/600 Tab if you are allergic to acebrophylline, ambroxol, or theophylline, suffer from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders, or have had a heart attack. However, inform your doctor if you have any of these conditions before taking Muciflo 100/600 Tab .
No, you are not recommended to smoke while taking Muciflo 100/600 Tab as it may reduce the effectiveness of Muciflo 100/600 Tab and also damage your lungs. Long-term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.
You are recommended to avoid histamine-rich foods such as tomatoes, wine, and processed foods. These may cause histamine intolerance by affecting the way histamine is broken down in the body, leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching, and rhinitis (runny and stuffy nose). Therefore, if you are allergic to histamine or cannot tolerate food and drinks rich in histamine, please inform your doctor before taking Muciflo 100/600 Tab .
No, you are not recommended to stop taking Muciflo 100/600 Tab without consulting your doctor. Doing so may worsen your cough and other breathing problems, causing recurring symptoms. Therefore, take Muciflo 100/600 Tab for as long as your doctor has prescribed it, and if you experience any difficulty while taking it, please consult your doctor.
No, Muciflo 100/600 Tab does not relieve sudden asthma symptoms. Therefore, it is advised to always carry a rescue inhaler to treat sudden asthma symptoms.
No, Muciflo 100/600 Tab is not an antibiotic. It is a combination of two drugs: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner).
Muciflo 100/600 Tab may cause side effects like diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. If the side effects persist or worsen, please consult your doctor.
Muciflo 100/600 Tab may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Muciflo 100/600 Tab before undergoing any laboratory tests.
Not only will taking higher doses of Muciflo 100/600 Tab not be more effective, but it can also cause side effects. It is important to avoid exceeding the recommended dose.
Store Muciflo 100/600 Tab at room temperature, in a dry place. Keep out of sight and reach of children.
No, do not take Muciflo 100/600 Tab if you are allergic to any of its components. Let the doctor know if you are allergic to Muciflo 100/600 Tab ; the doctor will prescribe alternate medicines.
If you miss a dose of Muciflo 100/600 Tab take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

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