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Written By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 9:31 AM IST

Mstarin Softgel Capsule is also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL). It contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells. This medicine is not recommended for children as safety and effectiveness have not been established.

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Composition :

MIDOSTAURIN-25MG

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Mstarin Softgel Capsule

Mstarin Softgel Capsule belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML). It is sometimes, also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL).

Mstarin Softgel Capsule contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.

Mstarin Softgel Capsule may cause certain side effects such as nausea, vomiting, headache, fever, musculoskeletal pain, and upper abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen. Take Mstarin Softgel Capsule as prescribed by your doctor.

Discontinue taking Mstarin Softgel Capsule and inform your physician if you observe any allergic reactions. Inform the doctor about your health condition and medications to rule out any side effects. Do not take Mstarin Softgel Capsule if you are pregnant or breastfeeding. This medicine is not recommended for children as safety and effectiveness have not been established.

Uses of Mstarin Softgel Capsule

Treatment of Acute myeloid leukaemia (AML), aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), and mast cell leukaemia (MCL)

Medicinal Benefits

Mstarin Softgel Capsule belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML) in patients who are FLT3 mutation-positive. It is also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL). Mstarin Softgel Capsule contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.

Side Effects of Mstarin Softgel Capsule

  • Nausea
  • Vomiting
  • Headache
  • Dizziness, light-headedness
  • Upper abdominal pain
  • Fever
  • Joint pain
  • Back pain
  • Throat pain
  • Mouth sores
  • Nose bleeds

Directions for Use

Take Mstarin Softgel Capsule with food. Swallow the medicine as a whole with water; do not crush or chew it. Take this medicine exactly as advised by the doctor.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Mstarin Softgel Capsule if you are allergic to any of its components, if you are taking medicines used to treat tuberculosis (rifampicin), epilepsy (carbamazepine or phenytoin), prostate cancer (enzalutamide), or herbal products (St. John’s Wort) or if you are pregnant or breastfeeding. Inform the doctor if you have any infections, heart disorders, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of low white blood cell count (fever, sore throat, mouth ulcers), lung problems (fever, chest pain, cough with or without mucous, trouble breathing or shortness of breath), or heart problems (chest pain or discomfort, fainting, dizziness, light-headedness, shortness of breath, blue discolouration of your lips, hands or feet, or swelling of your lower limbs).

Therapeutic Class

KINASE INHIBITORS

Drug-Drug Interactions

verifiedApollotooltip
MidostaurinZiprasidone
Critical
MidostaurinKetoconazole
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water to stay hydrated.

Habit Forming

No

How Mstarin Softgel Capsule Works

Mstarin Softgel Capsule contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.

What if I have taken an overdose of Mstarin Softgel Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Mstarin Softgel Capsule may include feeling cold, goosebumps, increased blood pressure (headache, flushing, blurred vision, pounding heartbeat) and trouble urinating. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.
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Alcohol

Consult your doctor

It is not known if alcohol affects Mstarin Softgel Capsule . Please consult your doctor.

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Pregnancy

Unsafe

Mstarin Softgel Capsule is not recommended during pregnancy as it may harm your unborn baby. Therefore, if you are pregnant or planning for pregnancy, talk to the doctor for advice.

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Breast Feeding

Unsafe

Mstarin Softgel Capsule may harm the baby. Avoid breastfeeding during treatment with Mstarin Softgel Capsule and for at least 4 months after stopping the treatment.

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Driving

Caution

Mstarin Softgel Capsule may cause dizziness and vertigo. Be cautious while driving or operating machinery.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Mstarin Softgel Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Mstarin Softgel Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

The safety and effectiveness of Mstarin Softgel Capsule in children below 18 years have not been established.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - MST0011

Author Details

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FAQs

Mstarin Softgel Capsule is used to treat Acute myeloid leukaemia (AML), aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), and mast cell leukaemia (MCL).
Mstarin Softgel Capsule works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.
If you miss a dose of Mstarin Softgel Capsule , take your next dose at the scheduled time. Avoid taking an extra dose to make up for the missed dose.
Mstarin Softgel Capsule may reduce fertility in men and women. Before starting the treatment, discuss with the doctor if you have any concerns regarding fertility.
Continue taking Mstarin Softgel Capsule even if you feel well. Do not stop taking Mstarin Softgel Capsule without talking to the doctor.
If you vomit after taking Mstarin Softgel Capsule , do take another dose. Continue with your regular dosing schedule and take the next dose at your scheduled time. If nausea or vomiting persists or worsens, consult the doctor.

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