Motivyst 300 Tablet is used to treat type 2 diabetes in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. Type 2 diabetes is a condition that occurs when there is either less insulin or the available insulin is not properly utilized by the body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Motivyst 300 Tablet contains Canagliflozin, a sodium-glucose cotransporters-2 (SGLT-2) (a protein present in the kidney) inhibitor that works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability.

In some cases, you may experience urinary tract infections, changes in urination (urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night), constipation, feeling thirsty, nausea, dizziness, and nausea. Most of these side effects of Motivyst 300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Motivyst 300 Tablet , let your doctor know if you are pregnant,  planning to get pregnant, or breastfeeding. Also, tell the doctor if you have/had any medical history of heart, liver, or kidney diseases. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Motivyst 300 Tablet works best when coupled with a healthy lifestyle like losing weight if you are overweight (BMI>25), eating fewer calories (low fat and sugary food), and being more physically active (at least 150min of activity every week).

Motivyst 300 Tablet belongs to the group of medicines called “anti-diabetic” indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons with high blood sugar levels, which is not controlled by diet and exercise alone. Motivyst 300 Tablet consists of “Canagliflozin”, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor responsible for the inhibition of SGLT-2 enzymes in the kidney. It prevents the reabsorption of glucose from the blood filtered through your kidney, thereby increasing the glucose excretion from your body when you pee.

• Urinary tract infections
• Changes in urination (including urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night)
• Constipation
• Feeling thirsty
• Nausea
• Blood tests may show changes in blood fat (cholesterol) levels
• Increases in the number of red blood cells in your blood

Motivyst 300 Tablet should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Before you start taking Motivyst 300 Tablet , tell your doctor if you have serious heart disease or if you have had a stroke, low blood pressure (hypotension), and severe liver or kidney disease. Motivyst 300 Tablet , when used with insulin, $ name may lower the blood sugar level, leading to hypoglycemia, which can be fatal. Your doctor may adjust the dose by lowering the dose of insulin or Motivyst 300 Tablet in this case. If you experience rapid weight loss, feeling sick or being sick, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth, or a different odour to your urine or sweat, talk to a doctor or go to the nearest hospital immediately.

Drug-Drug Interactions: Motivyst 300 Tablet interacts with other antidiabetic drugs (glimepiride, glipizide), diuretics (furosemide), medicines used to control seizures (carbamazepine, phenytoin, phenobarbital ), a medicine used to treat HIV infection (efavirenz, ritonavir), antibiotic used to treat tuberculosis (rifampicin), a medicine used to reduce cholesterol levels in the blood (cholestyramine), blood thinner (dabigatran) medicines used for certain heart problems (digoxin).

Drug-Food Interactions: Motivyst 300 Tablet may interact with household sugar and cause abdominal discomfort and stomach upset. Therefore one should avoid consuming foods rich in sugar. Additionally, Motivyst 300 Tablet interacts with St. John’s wort (a herbal medicine to treat depression).

Drug-Disease Interactions: People affected with heart diseases (like congestive heart failure and myocardial infarction), have sugar (glucose) and ketones (a type of chemical) in pee, severe kidney or liver disease, often get urinary tract infections, and alcoholism should avoid intake of Motivyst 300 Tablet .

• GLIMEPIRIDE
• GLIPIZIDE
• FUROSEMIDE
• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL
• EFAVIRENZ
• RITONAVIR
• RIFAMPICIN
• CHOLESTYRAMINE
• DABIGATRAN
• DIGOXIN

• A person should engage themself in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.

• A person should also maintain a healthy body weight to avoid obesity or high blood sugar; it can increase the risk of the onset of diabetes.

• A person should take low fat and a low sugar diet. For that, replace carbohydrates with whole grains, fruits, and vegetables as carbohydrates changed into sugars leading to high blood sugar levels.

• Try to avoid potatoes as they are high glycaemic foods that increase the risk of high sugar in the blood.

• A person should limit the consumption of alcohol and quit smoking.

• Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.

• Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.

You should have a test of glycated haemoglobin (HbA1C) every 3 months to check your blood glucose level control.

Type 2 diabetes: It is a chronic or lifelong condition in which the body's cells fail to respond to insulin and, in later stages, the body fails to produce enough insulin. It accounts for roughly 90% of all diabetes cases. Because of this condition, the body must rely on various energy sources in muscles, tissues, and organs. Early symptoms of this disease include constant hunger, lack of energy, fatigue, weight loss, excessive thirst, frequent urination, dry mouth, itchy skin, and blurry vision. Type 2 diabetes, also known as adult-onset diabetes, is most common in people in their forties and fifties. The risks of uncontrolled type 2 diabetes include retinal damage or blindness, limb loss, nerve problems, kidney problems, sexual dysfunction, and an increased risk of heart attack or stroke.