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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
MISONAC SR TABLET is used to reduce pain and swelling associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains diclofenac and misoprostol which works by inhibiting the release of chemical messengers that cause pain and protecting the stomach lining from acid. In some cases, this medicine may cause side effects such as diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Ordain Health Care Global Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About MISONAC SR TABLET

MISONAC SR TABLET belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

MISONAC SR TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Take MISONAC SR TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take MISONAC SR TABLET for as long as your doctor has prescribed it for you. You may experience diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of MISONAC SR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using the MISONAC SR TABLET, tell your doctor if you have had a heart attack or stroke, stomach or bowel disorder, liver disease, porphyria ( inherited blood disorder), asthma, high blood pressure, diabetes, and stomach or intestinal bleeding. Do not take MISONAC SR TABLET if you are a pregnant or breastfeeding woman. Consumption of alcohol should be avoided during the treatment with MISONAC SR TABLET as it may lead to an increased risk of liver damage. MISONAC SR TABLET is not recommended for use in children. Limit alcoholic beverages while on this medication.

Uses of MISONAC SR TABLET

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

MISONAC SR TABLET is used to treat aches and pains and musculoskeletal and joint pain problems due to arthritis. MISONAC SR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

How MISONAC SR TABLET Works

MISONAC SR TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MISONAC SR TABLET

  • Diarrhea
  • Stomach/abdominal pain
  • Nausea
  • Heartburn
  • Difficulty sleeping
  • Ulcers in the stomach or intestines
  • Drowsiness
  • Dizziness
  • Indigestion

What if I have taken an overdose of MISONAC SR TABLET

Take MISONAC SR TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include stomach pain, nausea, vomiting, diarrhoea, confusion, drowsiness, low muscle tone, uncontrollable shaking of a part of the body, seizures, shortness of breath, fever, and fast, pounding, or slow heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with MISONAC SR TABLET. Patients with stomach ulcers, gastric bleeding, heart failure, and high blood pressure should not take MISONAC SR TABLET. If pregnant or breastfeeding, do not take MISONAC SR TABLET without talking with the doctor. MISONAC SR TABLET is not recommended for children below 18 years old. Seek medical help immediately if you have signs of a heart attack or stroke. Stop using MISONAC SR TABLET and call your doctor immediately if you notice heart problems, kidney problems, liver problems, or stomach bleeding signs.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
MisoprostolDinoprostone
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with MISONAC SR TABLET:
Co-administration of MISONAC SR TABLET with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with MISONAC SR TABLET is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
MisoprostolDinoprostone
Severe
How does the drug interact with MISONAC SR TABLET:
Combined use of MISONAC SR TABLET and Dinoprostone can affect the metabolism of MISONAC SR TABLET.

How to manage the interaction:
Taking MISONAC SR TABLET and Dinoprostone together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MisoprostolOxytocin
Severe
How does the drug interact with MISONAC SR TABLET:
Coadministration of MISONAC SR TABLET and Oxytocin can enhance the action of oxytocin. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking MISONAC SR TABLET and Oxytocin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden or severe stomach pain, unexplained vaginal bleeding, Fast heart rate or low blood pressure in the pregnant person, diarrhea, or dehydration, consult to a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacEnoxaparin
Severe
How does the drug interact with MISONAC SR TABLET:
Taking MISONAC SR TABLET with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between MISONAC SR TABLET and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with MISONAC SR TABLET:
Co administration of MISONAC SR TABLET with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of MISONAC SR TABLET and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacSulindac
Severe
How does the drug interact with MISONAC SR TABLET:
Co-administration of MISONAC SR TABLET and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between MISONAC SR TABLET and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetorolac
Severe
How does the drug interact with MISONAC SR TABLET:
Coadministration of MISONAC SR TABLET and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of MISONAC SR TABLET and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacLomitapide
Severe
How does the drug interact with MISONAC SR TABLET:
Taking MISONAC SR TABLET with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between MISONAC SR TABLET and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacRamucirumab
Severe
How does the drug interact with MISONAC SR TABLET:
Co-administration of MISONAC SR TABLET and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of MISONAC SR TABLET and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPanobinostat
Severe
How does the drug interact with MISONAC SR TABLET:
Taking MISONAC SR TABLET with Panobinostat can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between MISONAC SR TABLET and Panobinostat, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

MISONAC SR TABLET Substitute

Substitutes safety advice
  • Misogesic SR Tablet 10's

    14.40per tablet
  • Lytix-DM SR Tablet 10's

    13.40per tablet
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Alcohol

Unsafe

Do not consume alcohol along with MISONAC SR TABLET as it can cause unpleasant side-effects like gastric bleeding.

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Pregnancy

Unsafe

Please consult your doctor if you are pregnant; your doctor will prescribe MISONAC SR TABLET only if the benefits outweigh the risks. Taking MISONAC SR TABLET in the last 20 weeks of pregnancy may cause serious kidney or heart problems in the unborn baby.

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Breast Feeding

Caution

While MISONAC SR TABLET may pass in the lactating mother's breast milk, So, do it is advisable to take it only if prescribed by your doctor.

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Driving

Caution

MISONAC SR TABLET may cause dizziness and drowsiness. So, if you observe such symptoms, do not drive.

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Liver

Caution

Limited information was available for the use of MISONAC SR TABLET in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using MISONAC SR TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of MISONAC SR TABLET in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using MISONAC SR TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

MISONAC SR TABLET not recommended for children under 18 years of age.

FAQs

MISONAC SR TABLET is used to reduce pain and swelling associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
MISONAC SR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. Thereby, MISONAC SR TABLET helps in relieving pain and swelling associated with different types of arthritis.
No, MISONAC SR TABLET is not a narcotic pain killer. It belongs to the non-steroidal anti-inflammatory drugs (NSAIDs) group of medications.
Yes, MISONAC SR TABLET can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.
MISONAC SR TABLET may increase the risk of heart problems such as heart attack, especially when used in high doses or for a prolonged duration, and in patients who are smokers, have high blood pressure, diabetes, or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking MISONAC SR TABLET. However, it is recommended to take MISONAC SR TABLET in the dose and for the duration as prescribed by your doctor.
MISONAC SR TABLET is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.
No, MISONAC SR TABLET does not cure arthritis. MISONAC SR TABLET is only used to relieve symptoms of arthritis such as joint pain, swelling, and stiffness.
MISONAC SR TABLET is used to treat pain associated with arthritis. If you have a toothache, it is recommended that you consult your doctor before using MISONAC SR TABLET.
MISONAC SR TABLET may cause gastrointestinal problems. Therefore, do not take MISONAC SR TABLET if you have acid reflux or abdominal pain without consulting the doctor.
It's generally not recommended to take MISONAC SR TABLET with blood pressure medication without consulting your doctor as it may increase blood pressure and reduce the effectiveness of blood pressure medications.
The common side effects of MISONAC SR TABLET include diarrhoea, stomach or abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of MISONAC SR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Exeltis - Ordain Health Care Global Pvt Ltd , Khivraj Complex - II, 4th Floor, No: 480, Anna Salai, Nandanam, Chennai - 600 035, Tamil Nadu, India.
Other Info - MIS0011

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