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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:44 PM IST

Mirel Injection is used in the treatment of ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. It contains Reteplase, which works by dissolving the blood clot that is blocking the heart's blood vessels. It may also treat a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart). Common side effects of Mirel Injection are bleeding, bruising at the injection site, nausea or vomiting.

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Synonym :

RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR

Composition :

RETEPLASE-18MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Mirel Injection

Mirel Injection is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.

Mirel Injection contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.

In some cases, Mirel Injection may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of Mirel Injection in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Mirel Injection

Treatment of ST-elevation myocardial infarction (STEMI)

Medicinal Benefits

Mirel Injection is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. Mirel Injection contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Side Effects of Mirel Injection

  • Bleeding
  • Bruising at the injection site
  • Vomiting
  • Nausea

Directions for Use

Mirel Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Mirel Injection should not be used if you are allergic to any of the components in Mirel Injection, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. Mirel Injection may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of Mirel Injection in children have not been established.

Therapeutic Class

MISCELLANEOUS

Drug-Drug Interactions

verifiedApollotooltip
ReteplaseIbrutinib
Severe
ReteplaseApixaban
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.

Habit Forming

No

How Mirel Injection Works

Mirel Injection contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.

What if I have taken an overdose of Mirel Injection

Since Mirel Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Consult your doctor

Limited information is available. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will prescribe only if the potential benefits outweigh the potential risk to the foetus.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Caution should be exercised whilst administering Mirel Injection to a nursing mother.

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Driving

Consult your doctor

Limited information is available. Please consult your doctor.

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Liver

Caution

The potential risks with the therapy of Mirel Injection may be increased in patients with severe liver dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

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Kidney

Caution

The potential risks of Mirel Injection therapy may be increased in patients with severe renal dysfunction and should be weighed against the anticipated benefits. Please consult your doctor.

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Children

Caution

The efficacy and safety of Mirel Injection in children have not been established.

Country of origin

India

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, Ttc Area Of Midc, Thane-Belapur Road, Rabale, Navi Mumbai 400 701.
Other Info - MIR0056

Author Details

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FAQs

Mirel Injection is used to treat ST-elevation myocardial infarction (STEMI).
Mirel Injection works by dissolving the blood clot that is blocking the heart's blood vessels.
Mirel Injection may increase the risk of bleeding. The sites of bleeding could be internal or external. Talk to your doctor if you have any concerns.
Heparin and Mirel Injection are incompatible. Mirel Injection should not be administered through an intravenous line containing heparin. Please consult your doctor if you have any concerns.
Mirel Injection will be administered by a healthcare professional in a clinical setting. Do not attempt to administer it yourself. A trained healthcare professional will ensure safe and proper administration.
Yes, Mirel Injection is safe when used under the doctor’s supervision. It is used in the treatment of ST-elevation myocardial infarction (STEMI). However, it may cause some side effects like bleeding, bruising at the injection site, nausea, or vomiting in some cases. You are advised to talk to your doctor if any of the side effects persist or worsen.
Mirel Injection may interact with anti-coagulants like heparin, enoxaparin, warfarin, phenindione, aspirin, dipyridamole, ticlopidine, clopidogrel, and vitamin K antagonists. So, it’s best to consult your doctor before taking anti-coagulants or any other medications along with Mirel Injection.
Mirel Injection helps prevent blood clots from forming in your legs, lungs, heart, and brain. You may not feel any immediate effects after taking the medicine, but that doesn't mean it's not working. Continue taking the medicine exactly as prescribed by your doctor, even if you don't notice any difference.
The common side effects of Mirel Injection may include bleeding, bruising at the injection site, nausea, or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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