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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Mikper 250mg/325mg Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. It contains Mefenamic acid and Paracetamol which helps reduce mild to moderate pain and inflammation at the injured or damaged site. It may cause common side effects such as nausea, vomiting, indigestion, heartburn, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Mikper 250mg/325mg Tablet

Mikper 250mg/325mg Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Mikper 250mg/325mg Tablet contains two drugs, Mefenamic acid and Paracetamol. Mikper 250mg/325mg Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Mikper 250mg/325mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Mikper 250mg/325mg Tablet may cause common side effects such as nausea, vomiting, indigestion, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Mikper 250mg/325mg Tablet may cause dizziness, so drive only if you are alert. Avoid consuming alcohol with Mikper 250mg/325mg Tablet as it could lead to increased dizziness and may increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Mikper 250mg/325mg Tablet

Treatment of Pain, inflammation, osteoarthritis, and rheumatoid arthritis.

Directions for Use

Swallow Mikper 250mg/325mg Tablet as a whole with a glass of water; do not chew or break the tablet/capsule.

Medicinal Benefits

Mikper 250mg/325mg Tablet contains two Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Mefenamic acid and Paracetamol. Mikper 250mg/325mg Tablet is used to treat pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. Mikper 250mg/325mg Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandin. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

How Mikper 250mg/325mg Tablet Works

Mikper 250mg/325mg Tablet contains two drugs, Mefenamic acid and Paracetamol. Mikper 250mg/325mg Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mikper 250mg/325mg Tablet

  • Indigestion
  • Nausea
  • Diarrhoea
  • Heartburn
  • Vomiting

What if I have taken an overdose of Mikper 250mg/325mg Tablet

Do not take more than the prescribed dose of Mikper 250mg/325mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Mikper 250mg/325mg Tablet if you are allergic to any of its contents; if you have severe heart, kidney or liver failure; or if you have suffered bleeding problems such as bleeding from the stomach or bowels while taking painkillers or if you have peptic ulcers or inflammatory bowel disease. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, dehydration, asthma, gastrointestinal bleeding, ulceration, perforation of the stomach and intestine, or liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Mikper 250mg/325mg Tablet may cause dizziness, so drive only if you are alert. Stop taking Mikper 250mg/325mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Mikper 250mg/325mg Tablet unless prescribed by the doctor.

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
Mefenamic acidMeloxicam
Critical

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
How does the drug interact with Mikper 250mg/325mg Tablet:
Coadministration of Mikper 250mg/325mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Mikper 250mg/325mg Tablet:
Co-administration of Mikper 250mg/325mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidIbrutinib
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Co-administration of Mikper 250mg/325mg Tablet with Ibrutinib can increase the risk or severity of bleeding, leading to serious blood loss.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Ibrutinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidHuman immunoglobulin
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Taking Human immunoglobulin with Mikper 250mg/325mg Tablet, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Mikper 250mg/325mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidDasatinib
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Co-administration of Mikper 250mg/325mg Tablet with Dasatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Dasatinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCidofovir
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Coadministration of cidofovir with Mikper 250mg/325mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Although taking Mikper 250mg/325mg Tablet and cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidIndometacin
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
The combined use of Indometacin and Mikper 250mg/325mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Mikper 250mg/325mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Mefenamic acidDeferasirox
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Coadministration of Mikper 250mg/325mg Tablet with Deferasirox can increase the risk or severity of gastric bleeding.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Deferasirox together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Co-administration of Mikper 250mg/325mg Tablet with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Mikper 250mg/325mg Tablet with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCabozantinib
Severe
How does the drug interact with Mikper 250mg/325mg Tablet:
Using cabozantinib together with Mikper 250mg/325mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Mikper 250mg/325mg Tablet and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Mikper 250mg/325mg Tablet Substitute

Substitutes safety advice
  • Big-PM Tablet 10's

    by AYUR

    6.12per tablet
  • Atnemol MF 250mg/325mg Tablet

    3.69per tablet
  • Mefisat-P Tablet

    3.60per tablet
  • Moltas M 250mg/325mg Tablet

    3.15per tablet
  • Tumin P 250mg/325mg Tablet

    4.77per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mikper 250mg/325mg Tablet as it may cause increased dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor before taking Mikper 250mg/325mg Tablet; your doctor will decide whether Mikper 250mg/325mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Mikper 250mg/325mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Please consult your doctor. Your doctor will prescribe the dose and duration based on your child's condition.

FAQs

Mikper 250mg/325mg Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis.
Mikper 250mg/325mg Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.
Mikper 250mg/325mg Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is tenderness and swelling in the joints.
Avoid taking Mikper 250mg/325mg Tablet if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.
Diarrhoea might be a side-effect of Mikper 250mg/325mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience severe diarrhea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Mikper 250mg/325mg Tablet is used to relieve menstrual (period) pain and management of excessively heavy periods. Take Mikper 250mg/325mg Tablet only as prescribed by the doctor.
Mikper 250mg/325mg Tablet is generally prescribed for short-term use. Do not take Mikper 250mg/325mg Tablet for longer durations as it might increase the risk of kidney problems and stomach bleeding.

Country of origin

India
Other Info - MI38721

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