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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Migraneck Tablet is a combination medicine used in the treatment of migraine. This medicine works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches and thus helps relieve the symptoms of migraine and prevent the worsening of the attack. Common side effects include stomach upset, dizziness, dry mouth, constipation, and insomnia.
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Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Migraneck Tablet

Migraneck Tablet is a combination medicine indicated to treat and prevent migraine. Migraneck Tablet is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. Migraine is a neurological condition that is characterized by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.
 
Migraneck Tablet is a combination of four drugs, namely: Ergotamine tartrate (ergot alkaloid), caffeine (methylxanthine), prochlorperazine maleate (anti-emetic) and paracetamol (analgesic). Ergotamine tartrate works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.
 
Take Migraneck Tablet with or without food. Swallow Migraneck Tablet as a whole with a glass of water; do not chew, or break the tablet. Take Migraneck Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Migraneck Tablet contains paracetamol, do not take other medicines containing paracetamol along with Migraneck Tablet . Do not take Migraneck Tablet if you are pregnant or breastfeeding. Migraneck Tablet causes drowsiness and dizziness, so drive with caution. Migraneck Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Migraneck Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects.

Uses of Migraneck Tablet

Treatment of Migraine

Directions for Use

Take Migraneck Tablet with or without food. Swallow Migraneck Tablet as a whole with a glass of water; do not chew or break the tablet. Your doctor will decide how long you need to take Migraneck Tablet based on your medical condition.

Medicinal Benefits

Migraneck Tablet contains Ergotamine tartrate, caffeine, prochlorperazine maleate, and paracetamol. Migraneck Tablet is used to treat and prevent migraines. Ergotamine tartrate is an ergot alkaloid that works by constricting blood vessels in the brain and altering blood flow patterns associated with headaches. Caffeine is a methylxanthine that increases the vasoconstriction effect (narrowing of blood vessels). Prochlorperazine maleate is an anti-emetic that prevents migraine-related nausea and vomiting by altering the effects of neurotransmitters. Paracetamol is an analgesic that prevents the release of prostaglandins, which cause pain. Migraneck Tablet is used to relieve migraine symptoms and prevent the attack from worsening.

How Migraneck Tablet Works

Migraneck Tablet is a combination of four drugs, namely: Ergotamine tartrate (ergot alkaloid), caffeine (methylxanthine), prochlorperazine maleate (anti-emetic) and paracetamol (analgesic). Ergotamine tartrate works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Migraneck Tablet

  • Stomach upset
  • Dizziness
  • Dry mouth
  • Constipation
  • Insomnia (trouble sleeping)

What if I have taken an overdose of Migraneck Tablet

Do not take more than the prescribed dose of Migraneck Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Migraneck Tablet if you are allergic to any of its contents; if you have/had heart problems, blood circulation problems, or if you are taking antibiotics, anti-fungal, anti-HIV, or other anti-migraine medicines. Migraneck Tablet , when taken along with antibiotics, anti-fungal, and anti-HIV drugs, could lead to unpleasant side effects such as poor blood flow to hands, feet, or brain. Migraneck Tablet contains paracetamol, do not take other medicines containing paracetamol along with Migraneck Tablet . Inform your doctor before taking Migraneck Tablet if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take Migraneck Tablet if you are pregnant or breastfeeding. Migraneck Tablet may cause drowsiness and dizziness, so drive only if you are alert. Migraneck Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Migraneck Tablet as it could lead to increased drowsiness. Do not take other NSAIDs for pain relief while taking Migraneck Tablet unless prescribed. 

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Migraneck Tablet:
Coadministration of metoclopramide and Migraneck Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Migraneck Tablet together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Migraneck Tablet:
Coadministration of mesoridazine and Migraneck Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Migraneck Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Migraneck Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migraneck Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Migraneck Tablet:
Coadministration of tranylcypromine with Migraneck Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Migraneck Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineLinezolid
Critical
How does the drug interact with Migraneck Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migraneck Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Migraneck Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migraneck Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
ErgotamineRasagiline
Critical
How does the drug interact with Migraneck Tablet:
Taking Migraneck Tablet and Rasagiline together can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Rasagiline and Migraneck Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, and diarrhea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
ErgotamineSumatriptan
Critical
How does the drug interact with Migraneck Tablet:
Coadministration of Migraneck Tablet with Sumatriptan can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Sumatriptan and Migraneck Tablet, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
ErgotamineRitonavir
Critical
How does the drug interact with Migraneck Tablet:
Taking Migraneck Tablet with ritonavir may significantly increase the blood levels and effects of Migraneck Tablet.

How to manage the interaction:
Taking Migraneck Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor. Do not discontinue any medications without consulting a doctor.
ErgotamineCeritinib
Critical
How does the drug interact with Migraneck Tablet:
Taking Migraneck Tablet with ceritinib can significantly increase the blood levels and effects of Migraneck Tablet.

How to manage the interaction:
Taking Ceritinib with Migraneck Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and trouble speaking. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CAFFEINE-100MG+ERGOTAMINE TARTRATE-1MG+PARACETAMOL-250MG+PROCHLORPERAZINE MALEATE-2.5MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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CAFFEINE-100MG+ERGOTAMINE TARTRATE-1MG+PARACETAMOL-250MG+PROCHLORPERAZINE MALEATE-2.5MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grape juice or grape fruit can increase the blood levels of ergotamine in the body. Consumption of grape juice increases the effect of caffeine. Limit your consumption of grapefruit and grapefruit juice during treatment with ergotamine and caffeine.

Diet & Lifestyle Advise

  • Maintaining a healthy diet and exercising regularly helps improve overall health and boost self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Migraneck Tablet as it may increase drowsiness.

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Pregnancy

Unsafe

Migraneck Tablet is not recommended for use in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking this medicine.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Migraneck Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Migraneck Tablet should not be given to children as safety and effectiveness were not established.

FAQs

Migraneck Tablet is a combination medicine indicated to treat and prevent migraine. Migraneck Tablet is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack.

Migraneck Tablet contains Ergotamine tartrate, caffeine, prochlorperazine maleate, and paracetamol. Ergotamine tartrate works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.

Dry mouth could be a side effect of Migraneck Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Orthostatic hypotension could be a side-effect of Migraneck Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better. People taking Migraneck Tablet are advised to monitor their blood pressure levels regularly to avoid such unpleasant events.

Do not discontinue Migraneck Tablet without consulting your doctor, as it could lead to recurring or worsening of symptoms. To treat your condition effectually, continue taking Migraneck Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Migraneck Tablet .

Do not take Migraneck Tablet along with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir). Migraneck Tablet contains ergotamine and caffeine, which, when taken along with these drugs, could lead to unpleasant side effects such as poor blood flow to the hands, feet, or brain.

Migraneck Tablet may cause constipation. Eat high-fibre foods and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - MIG0157

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