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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
MIFEONE 10MG SOFTGEL CAPSULE is used in combination with Misoprostol to induce a medical abortion. It is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help. It contains Mifepristone, which works by blocking the effect of progesterone (female hormone), needed to sustain a pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

MIFEPRISTONE-10MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About MIFEONE 10MG SOFTGEL CAPSULE

MIFEONE 10MG SOFTGEL CAPSULE belongs to the class of medication called 'progestin antagonist' used in combination with Misoprostol to induce a medical abortion. MIFEONE 10MG SOFTGEL CAPSULE is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

MIFEONE 10MG SOFTGEL CAPSULE contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for MIFEONE 10MG SOFTGEL CAPSULE to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete.

Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.

MIFEONE 10MG SOFTGEL CAPSULE should be taken in dose and duration as advised by the doctor, preferably with food. It would be best to take it at a fixed time every day. It is a tablet and should be taken orally with a glass of water. In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of MIFEONE 10MG SOFTGEL CAPSULE subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention.

MIFEONE 10MG SOFTGEL CAPSULE should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting MIFEONE 10MG SOFTGEL CAPSULE if you have or ever had an ectopic pregnancy (when the fetus grows in the fallopian tube), using an intrauterine device, or if you are breastfeeding, any bleeding disorder or heart problem. Do not do strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

Uses of MIFEONE 10MG SOFTGEL CAPSULE

Treatment of Medical abortion

Directions for Use

MIFEONE 10MG SOFTGEL CAPSULE should be taken in dose and duration as prescribed by your doctor. Do not chew or crush it; swallow it as a whole.

Medicinal Benefits

MIFEONE 10MG SOFTGEL CAPSULE contains Mifepristone, which is taken in a regimen with Misoprostol to induce medical abortion or terminate a pregnancy before 70 days. It works by blocking the effect of progesterone (female hormone) needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for MIFEONE 10MG SOFTGEL CAPSULE to show effect.

How MIFEONE 10MG SOFTGEL CAPSULE Works

MIFEONE 10MG SOFTGEL CAPSULE contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MIFEONE 10MG SOFTGEL CAPSULE

  • Weakness
  • Nausea
  • Uterine cramps
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Infection following abortion
  • Uterine bleeding

What if I have taken an overdose of MIFEONE 10MG SOFTGEL CAPSULE

Do not take more than the prescribed dose of MIFEONE 10MG SOFTGEL CAPSULE as it may cause overdose. The symptoms of overdose include severe vaginal bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Women who have an ectopic pregnancy (a pregnancy outside of the uterus, problems with the adrenal glands (the glands near the kidneys), currently taking corticosteroid therapy (medications), have an allergic reaction to mifepristone, misoprostol or similar drugs, have bleeding problems or taking the blood-thinning drug (warfarin, clopidogrel, aspirin, heparin etc.) should not use MIFEONE 10MG SOFTGEL CAPSULE and contact doctor. After using MIFEONE 10MG SOFTGEL CAPSULE if you start feeling sleepy, do not drive or operate heavy machinery. If you use an intrauterine device (IUD), please remove it before taking the MIFEONE 10MG SOFTGEL CAPSULE . Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (herbal supplements to treat mild depression) and grapefruit juice should not be taken when taking MIFEONE 10MG SOFTGEL CAPSULE as it is known to interact. 

Drug-Drug Interactions

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MifepristoneMesoridazine
Critical
MifepristoneApixaban
Critical

Drug-Drug Interactions

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MifepristoneMesoridazine
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Co-administration of Mesoridazine with Mefipristone can increase the risk of an abnormal heart rhythm, low potassium levels in the body.

How to manage the interaction:
Taking Mesoridazine with MIFEONE 10MG SOFTGEL CAPSULE 14'S is not recommended, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
MifepristoneApixaban
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
MIFEONE 10MG SOFTGEL CAPSULE 14'S and Apixaban co-administration have been associated with more severe vaginal bleeding in women.

How to manage the interaction:
Taking Apixaban with MIFEONE 10MG SOFTGEL CAPSULE 14'S together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
MifepristoneFentanyl
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Taking fentanyl and MIFEONE 10MG SOFTGEL CAPSULE 14'S may significantly increase the blood levels of fentanyl, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between MIFEONE 10MG SOFTGEL CAPSULE 14'S and fentanyl, they can be taken together if advised by a doctor. Do not stop using any medications without talking to your doctor.
MifepristoneBudesonide
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Using MIFEONE 10MG SOFTGEL CAPSULE 14'S together with budesonide may significantly reduce the effects of budesonide.

How to manage the interaction:
Taking Budesonide with MIFEONE 10MG SOFTGEL CAPSULE 14'S is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneLovastatin
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
When MIFEONE 10MG SOFTGEL CAPSULE 14'S is taken with Lovastatin, it can increase the risk of side effects including rhabdomyolysis (a condition that causes your muscles to break down (disintegrate), which leads to muscle death).

How to manage the interaction:
Taking Lovastatin with MIFEONE 10MG SOFTGEL CAPSULE 14'S is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneFluticasone furoate
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Using Fluticasone furoate with MIFEONE 10MG SOFTGEL CAPSULE 14'S can reduce the effect of fluticasone furoate.

How to manage the interaction:
Taking Fluticasone furoate with MIFEONE 10MG SOFTGEL CAPSULE 14'S is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneTolvaptan
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
When Tolvaptan is taken with MIFEONE 10MG SOFTGEL CAPSULE 14'S, it may increase the levels of tolvaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan and MIFEONE 10MG SOFTGEL CAPSULE 14'S together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
MifepristoneMidazolam
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Co-administration of MIFEONE 10MG SOFTGEL CAPSULE 14'S and Midazolam may significantly increase Midazolam blood levels and effects, which increases the risk of side effects.

How to manage the interaction:
Although taking MIFEONE 10MG SOFTGEL CAPSULE 14'S and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MifepristoneEnoxaparin
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Combining MIFEONE 10MG SOFTGEL CAPSULE 14'S with Enoxaparin can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Enoxaparin with MIFEONE 10MG SOFTGEL CAPSULE 14'S is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneDefibrotide
Critical
How does the drug interact with MIFEONE 10MG SOFTGEL CAPSULE 14'S:
Co-administration of MIFEONE 10MG SOFTGEL CAPSULE 14'S with Defibrotide can increase the risk and severity of vaginal bleeding in women.

How to manage the interaction:
Taking MIFEONE 10MG SOFTGEL CAPSULE 14'S with Defibrotide is not recommended, but it can be taken if prescribed by the doctor. However, if you experience excessive, prolonged vaginal bleeding, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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MIFEPRISTONE-10MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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MIFEPRISTONE-10MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may increase the effects of MIFEONE 10MG SOFTGEL CAPSULE 14'S. Avoid consumption of grape juice while taking MIFEONE 10MG SOFTGEL CAPSULE 14'S. However, if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, swelling, and high blood pressure, consult the doctor.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Get an ultrasound to check if the abortion is done completely to avoid unwanted complications.
  • Try to include heart-healthy omega-3 fatty acid-containing foods or drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIPROGESTERONE

MIFEONE 10MG SOFTGEL CAPSULE Substitute

Substitutes safety advice
  • FIBROEASE 10MG TABLET 1'S

    by AYUR

    62.64per tablet
  • Goefibro-M 10mg Tablet 10's

    by AYUR

    44.45per tablet
  • Mifiact 10mg Tablet 10's

    by AYUR

    19.17per tablet
  • Fibrocede-10 Tablet 10's

    by Others

    29.43per tablet
  • Mifiact-10 Tablet 10's

    by Others

    21.30per tablet
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Alcohol

Unsafe

Alcohol is known to cause excessive drowsiness if taken along with MIFEONE 10MG SOFTGEL CAPSULE and increase uterine bleeding.

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Pregnancy

Unsafe

MIFEONE 10MG SOFTGEL CAPSULE is used for medical abortion. If taken in pregnancy, it can lead to abortion.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before prescribing MIFEONE 10MG SOFTGEL CAPSULE ; your doctor will decide whether MIFEONE 10MG SOFTGEL CAPSULE can be taken by breastfeeding mothers or not.

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Driving

Unsafe

MIFEONE 10MG SOFTGEL CAPSULE may reduce alertness or induce sleep and dizziness. If you experience these symptoms, don't drive or operate machinery.

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Liver

Caution

MIFEONE 10MG SOFTGEL CAPSULE to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

MIFEONE 10MG SOFTGEL CAPSULE to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

MIFEONE 10MG SOFTGEL CAPSULE is not recommended for children below the age of 12. The safety and effectiveness of MIFEONE 10MG SOFTGEL CAPSULE have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give MIFEONE 10MG SOFTGEL CAPSULE or not.

FAQs

MIFEONE 10MG SOFTGEL CAPSULE is used in combination with Misoprostol to induce a medical abortion. MIFEONE 10MG SOFTGEL CAPSULE is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.
No, MIFEONE 10MG SOFTGEL CAPSULE should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine bleeding.
No, the MIFEONE 10MG SOFTGEL CAPSULE is not known to affect any future chances of fertility. MIFEONE 10MG SOFTGEL CAPSULE is used for medical abortion.
If you miss a dose of MIFEONE 10MG SOFTGEL CAPSULE , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
After taking MIFEONE 10MG SOFTGEL CAPSULE , you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.
No, the MIFEONE 10MG SOFTGEL CAPSULE does not affect fertility. Use contraception during sexual intercourse as it may lead to unwanted pregnancy if you are not planning it.
Some of the common side effects of MIFEONE 10MG SOFTGEL CAPSULE are nausea, weakness, fever/chills, vomiting, headache, diarrhoea, and dizziness.
MIFEONE 10MG SOFTGEL CAPSULE contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the development of the pregnancy is stopped.
No, taking more than the prescribed dose of MIFEONE 10MG SOFTGEL CAPSULE will not make it more effective and could be dangerous. Please follow the dosage as prescribed by your doctor to avoid potential side effects or complications.
Please inform your doctor if you have a history of liver disease before using MIFEONE 10MG SOFTGEL CAPSULE . The dosage may need to be adjusted by your doctor, as liver impairment can affect how the drug is metabolized.
Swallow MIFEONE 10MG SOFTGEL CAPSULE as a whole with water; do not crush or chew it. The doctor will determine the dose based on your condition.
After taking MIFEONE 10MG SOFTGEL CAPSULE , you may experience cramping or bleeding in the uterus as the medication works to block the hormone progesterone and prepare your body for the next step in the abortion process. Typically, bleeding begins within 24-48 hours after taking MIFEONE 10MG SOFTGEL CAPSULE . It is common to experience other side effects such as nausea, vomiting, diarrhoea, dizziness, or infection following the abortion. Follow-up with your doctor is essential to ensure that the process is complete.

Country of origin

INDIA
Other Info - MIF0033

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