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  3. Midorise 5 Tablet 10's

Midorise 5 Tablet 10's, Pack of 10 TabletS
Midorise 5 Tablet 10's, Pack of 10 TabletS
Midorise 5 Tablet 10's, Pack of 10 TabletS
Midorise 5 Tablet 10's, Pack of 10 TabletS
Midorise 5 Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Midorise 5 Tab is used to treat orthostatic hypotension (sudden lowering in blood pressure on standing). It contains midodrine, which works by tightening the blood vessels, thereby increasing blood pressure. In some cases, this medicine may cause side effects such as headache, nausea, heartburn, and pain during urination. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

MIDODRINE HYDROCHLORIDE

Composition :

MIDODRINE-5MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Midorise 5 Tab

Midorise 5 Tab belongs to a category of medications called ‘Antihypotensives’ primarily used to treat hypotension (low blood pressure). Hypotension is when blood pressure drops below the normal range, reducing cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and risk of injury from falls.

Midorise 5 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Take Midorise 5 Tab as prescribed by your doctor. Depending on your medical condition, you are advised to take Midorise 5 Tab for as long as your doctor prescribes it. Some people may experience Supine hypertension, Reflex bradycardia, Arrhythmias, Rash, Nausea, Vomiting, Dyspepsia, Headache, and Urinary retention. Most of these side effects of Midorise 5 Tab do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Midorise 5 Tab or other medicines. If you are a pregnant woman or nursing mother, do not consume Midorise 5 Tab without first consulting your doctor. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Uses of Midorise 5 Tab

Treatment of Idiopathic postural hypotension or hypotension.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Midorise 5 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

How Midorise 5 Tab Works

Midorise 5 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Midorise 5 Tab

  • Supine hypertension

  • Chest pain

  • Palpitations

  • Headache

  • Blurred vision

  • Reflex bradycardia

  • Arrhythmias

  • Rash

  • Nausea

  • Vomiting

  • Dyspepsia

  • Urinary retention

What if I have taken an overdose of Midorise 5 Tab

Take Midorise 5 Tab only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include palpitations, headache, pounding in ears, goose bumps, blurred vision, difficulty urinating, and cold sensation. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Midorise 5 Tab or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. If you get pregnant during treatment with Midodrine, you must stop the treatment immediately once the pregnancy is confirmed. It should not be used in children below 18 years. Midodrine is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
MidodrineDoxapram
Severe

Drug-Drug Interactions

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MidodrineDihydroergotamine
Critical
How does the drug interact with Midorise 5 Tablet:
Coadministration of Dihydroergotamine with Midorise 5 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Dihydroergotamine with Midorise 5 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any of these symptoms like headaches, abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, eye redness, confusion, or slurred speech, consult a doctor right away. Do not discontinue any medications without consulting a doctor.
MidodrineDoxapram
Severe
How does the drug interact with Midorise 5 Tablet:
Coadministration of Midorise 5 Tablet with doxapram can increase effect of Doxapram.

How to manage the interaction:
Taking Doxapram with Midorise 5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MidodrineMethysergide
Severe
How does the drug interact with Midorise 5 Tablet:
Using methysergide maleate together with Midorise 5 Tablet may cause significant increases in blood pressure.

How to manage the interaction:
Co-administration of Midorise 5 Tablet with Methysergide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
MidodrineErgotamine
Severe
How does the drug interact with Midorise 5 Tablet:
Using ergotamine together with Midorise 5 Tablet can increase the risk or severity of high blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Midorise 5 Tablet and Ergotamine, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discolouration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MidodrineLinezolid
Severe
How does the drug interact with Midorise 5 Tablet:
Taking Midorise 5 Tablet along with linezolid could increase the risk or severity of high blood pressure.

How to manage the interaction:
Although taking linezolid with Midorise 5 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
MidodrineIobenguane (131i)
Severe
How does the drug interact with Midorise 5 Tablet:
Coadministration of Midorise 5 Tablet with Iobenguane can cause a decrease in the absorption of Iobenguane resulting in a low treatment outcomes.

How to manage the interaction:
Co-administration of Midorise 5 Tablet with Iobenguane (131i) can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add foods with high vitamin B12, including eggs, fortified cereals, and nutritional yeast, to your daily diet.

  • Salty foods can increase blood pressure. Try eating canned soup, cottage cheese, olives, and pickled items.
  • Drink coffee and caffeinated tea, which may increase blood pressure by stimulating the cardiovascular system.
  • Eat small meals more frequently; large meals may drop in blood pressure as your body works harder to digest larger meals.
  • Drink more water and limit alcohol; dehydration lowers blood pressure.
  • Change body position by standing up slowly.
  • Avoid prolonged bed rest.
  • If you exercise outdoors in extreme heat, take frequent breaks.
  • Avoid spending a long time in saunas, hot tubs, and steam rooms which cause dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES

Midorise 5 Tab Substitute

Substitutes safety advice

  • Inramed 5 Tablet 10's

    by AYUR

    ₹81.00per tablet

  • Xidorin 5 mg Tablet 10's

    by Others

    ₹78.30per tablet

  • Midgeo 5 Tablet 10's

    by Others

    ₹49.50per tablet

  • Aladrine 5 mg Tablet 30's

    by Others

    ₹76.50per tablet

  • Aladrine 5 mg Tablet 10's

    by Others

    ₹76.50per tablet

Product Substitutes

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Alcohol

Caution

Consuming alcohol along with Midorise 5 Tab is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Midorise 5 Tab in breastfeeding/nursing mothers.

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Driving

Caution

Patients who experience dizziness or lightheadedness while receiving Midodrine should refrain from operating machinery.

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Liver

Caution

Limited information is available on the use of Midorise 5 Tab in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

bannner image

Kidney

Caution

Limited information is available on the use of Midorise 5 Tab in patients with Kidney disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

bannner image

Children

Unsafe

Midorise 5 Tab is not recommended for children below 18 years of age.

FAQs

Midorise 5 Tab is used to treat idiopathic postural hypotension or hypotension (low blood pressure)

Midorise 5 Tab contains the active ingredient midodrine hydrochloride, which acts on the blood vessels via the sympathetic nervous system to correct imbalances of blood distribution. This should help relieve the symptoms you might suffer, such as dizziness, fainting, blurred vision, and weakness when sitting or standing up.

Do not stop taking Midorise 5 Tab on your own. Depending on your medical condition, you are advised to take Midorise 5 Tab for as long as your doctor has prescribed it for you. Do not hesitate to speak with your doctor if you experience difficulty while taking Midorise 5 Tab .

Midorise 5 Tab is contraindicated in patients with severe organic heart disease, congestive heart failure, thyrotoxicosis, phaeochromocytoma, acute renal disease, severe renal insufficiency, urinary retention, narrow-angle glaucoma, hyperthyroidism, known hypersensitivity to any component of the product. And also, Patients with a history of CVA should be monitored closely.

Midorise 5 Tab is metabolised to desglymidodrine, an active metabolite that activates alpha-1-adrenergic receptors on arterioles and venules, causing smooth muscle contraction and blood pressure increase. Midodrine may cause a drop in heart rate due to the vagal reflex.

The side effects of Midorise 5 Tab include nausea, vomiting, indigestion, supine hypertension (high blood pressure while lying down), and dysuria (painful or uncomfortable urination). If these side effects persist or worsen, please consult your doctor.

Yes, Midorise 5 Tab may cause high blood pressure when you are lying flat on your back (supine hypertension). Midorise 5 Tab should only be used by people whose low blood pressure affects their daily activities and in people who could not be treated successfully with other therapies.

You are advised not to lie down immediately after taking Midorise 5 Tab due to the risk of supine hypertension (high blood pressure when you are lying flat on your back). Therefore, it is recommended to take the final dose of the day at least 4 hours before bedtime. By elevating the head, you can reduce the risk of supine hypertension during the night.

Midorise 5 Tab may take about 1 hour to show its effects. Though the effect lasts for about 2-3 hours, the action lasts for a short time only.

Take Midorise 5 Tab exactly as advised by your doctor. It is taken orally with or without food. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Midorise 5 Tab is not recommended for patients who are allergic to any of its components, who have unusually slow heart rate, severe heart disease, high blood pressure, conditions causing tightening of the arteries, urinary retention (when the bladder cannot empty properly), overactive thyroid, enlarged prostate gland, pheochromocytoma (tumour of the adrenal medulla), acute or severe kidney disease, poor vision as a result of diabetes and narrow-angle glaucoma (elevated pressure in the eye).

Before starting Midorise 5 Tab , you may need to get your liver and kidney function tests done and check your blood pressure. After starting the treatment, keep a constant track of your heart rate and blood pressure, especially after lying down.

Symptoms of supine hypertension include shortness of breath, chest pain, palpitations (abnormalities of heartbeat), blurred vision, and headache. If you develop these symptoms, consult your doctor immediately. The doctor may lower the dose of Midorise 5 Tab or discontinue treatment if the symptoms persists.

You should be cautious while using Midorise 5 Tab and metoprolol together as it can decrease your heart rate significantly. If you experience dizziness, fainting and slow pulse, inform your doctor as the dose of these medicines may need to be adjusted. However, please consult your doctor before using other medicines with Midorise 5 Tab .

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - MID0071

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:47 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.dbth.nhs.uk/wp-content/uploads/2017/10/Midodrine-Information-Leaflet.pdf
  2. https://www.medicines.org.uk/emc/product/12496/smpc#gref
  3. https://www.medicines.org.uk/emc/files/pil.12496.pdf
  4. https://www.drugs.com/drug-interactions/midodrine.html
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