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About Microtaz 1.125 gm Injection
Microtaz 1.125 gm Injection belongs to the 'Antibiotics' class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.
Microtaz 1.125 gm Injection contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of 'Penicillin antibiotics.' It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Microtaz 1.125 gm Injection, Tazobactam works by preventing bacteria from destroying Piperacillin.
Microtaz 1.125 gm Injection will be administered by a healthcare professional. Like all medicines, Microtaz 1.125 gm Injection also causes side effects, although not everybody gets them. Common side effects of Microtaz 1.125 gm Injection include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly.
Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits before using Microtaz 1.125 gm Injection. Do not use Microtaz 1.125 gm Injection while having vaccinations with live bacterial vaccines (typhoid vaccine) since Microtaz 1.125 gm Injection may affect vaccines' activity. Microtaz 1.125 gm Injection should be used during pregnancy only if the doctor advises you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking Microtaz 1.125 gm Injection.
Uses of Microtaz 1.125 gm Injection
Medicinal Benefits
Microtaz 1.125 gm Injection contains two medicines, namely: Piperacillin and Tazobactam. Piperacillin is a Penicillin antibiotic. It acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Microtaz 1.125 gm Injection, Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, Microtaz 1.125 gm Injection helps treat various bacterial infections of the stomach, lungs, skin and uterus.
Side Effects of Microtaz 1.125 gm Injection
Directions for Use
Storage
Drug Warnings
If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, or heart or liver diseases, please inform your doctor before starting Microtaz 1.125 gm Injection. Please seek medical advice if you are pregnant or breastfeeding before taking Microtaz 1.125 gm Injection. Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Safety and efficacy of Microtaz 1.125 gm Injection in children less than two months of age have not been established.
Therapeutic Class
Drug-Drug Interactions
Drug-Food Interactions
Diet & Lifestyle Advise
Habit Forming
How Microtaz 1.125 gm Injection Works
What if I have taken an overdose of Microtaz 1.125 gm Injection
Alcohol
Caution
Avoid alcohol consumption while taking Microtaz 1.125 gm Injection to prevent unpleasant side-effects, such as nausea and vomiting.
Pregnancy
Caution
Microtaz 1.125 gm Injection should be used with caution during pregnancy since it crosses the placenta in humans. Please consult your doctor before taking Microtaz 1.125 gm Injection if you are pregnant or planning to conceive.
Breast Feeding
Caution
There is limited data on how Microtaz 1.125 gm Injection affects breastfed infants. Microtaz 1.125 gm Injection is excreted into breast milk. Please consult your doctor before taking Microtaz 1.125 gm Injection if you are breastfeeding.
Driving
Caution
It is unknown whether Microtaz 1.125 gm Injection affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking Microtaz 1.125 gm Injection, do not drive or operate any machinery.
Liver
Caution
Let your doctor know if you have any history of liver diseases before taking Microtaz 1.125 gm Injection. Your doctor will prescribe Microtaz 1.125 gm Injection only if the benefits outweigh the risk.
Kidney
Caution
Penicillin antibiotics are easily removed by dialysis. Beta-lactam antibiotics like Tazobactam should be cautiously administered in patients with renal impairment. Prolonged use of Microtaz 1.125 gm Injection may cause nephrotoxicity and alterations in renal function, hence please let your doctor know if you have any history of kidney diseases before taking Microtaz 1.125 gm Injection. Your doctor will prescribe Microtaz 1.125 gm Injection only if the benefits outweigh the risk.
Children
Caution
Safety and efficacy of Microtaz 1.125 gm Injection in children less than two months of age have not been established.
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