Metstol 100mg Tablet belongs to the 'antibacterials' class of drugs, primarily used to treat bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder) and respiratory tract. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.

Metstol 100mg Tablet contains 'Trimethoprim,' an antibacterial drug. Trimethoprim is a folic acid inhibitor that inhibits tetrahydrofolic acid formation (a folic acid derivative essential for developing proteins and nucleic acids). Thus, Metstol 100mg Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Like all medicines, Metstol 100mg Tablet also causes side effects, although not everybody gets them. Common side effects of Metstol 100mg Tablet include diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to doctor before starting Metstol 100mg Tablet. Do not use Metstol 100mg Tablet while having vaccinations with live bacterial vaccines (typhoid vaccine) since Metstol 100mg Tablet may affect vaccines' activity. Metstol 100mg Tablet can make your skin more sensitive to the sun, hence wear sunscreen when you step out. It is advised to consult your doctor if you are pregnant or breastfeeding before taking Metstol 100mg Tablet.

Metstol 100mg Tablet contains 'Trimethoprim,' an antibacterial drug that treats bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder), and respiratory tract. It also helps in treating chest infections and acne. Metstol 100mg Tablet is a folic acid inhibitor and inhibits tetrahydrofolic acid formation (a folic acid derivative essential for the formation of proteins and nucleic acids). Thus, Metstol 100mg Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. Metstol 100mg Tablet is also used to prevent the recurrence of urinary tract infections.

• Diarrhoea
• Nausea
• Vomiting
• Stomach upset 
• Loss of appetite 
• Changes in taste 
• Headache 

Older patients may be more prone to side effects when they have a history of hyperkalemia while using Metstol 100mg Tablet. Please inform your doctor if you are undergoing dialysis treatment since Metstol 100mg Tablet is moderately removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Please undergo an examination to rule out CDAD's chances if you experience diarrhoea following Metstol 100mg Tablet therapy. Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Metstol 100mg Tablet may affect vaccines' activity. Metstol 100mg Tablet may induce photosensitivity and make your skin more sensitive to the sun; hence, wear sunscreen when you step out. Please seek medical advice if you are pregnant or breastfeeding before taking Metstol 100mg Tablet.

Drug-Drug Interaction: Metstol 100mg Tablet may interact with anticoagulants (warfarin, heparin), anti-cancer drugs (methotrexate), anti-diabetics (repaglinide), heart-related drugs (procainamide, digoxin), anti-malarial drugs (pyrimethamine and dapsone), fits medicine (phenytoin), antibiotics (rifampicin), fluid retention drugs (spironolactone, amiloride), blood pressure medicines, and potassium supplements.

Drug-Food Interaction: Avoid alcohol consumption while taking Metstol 100mg Tablet to prevent unpleasant side effects.

Drug-Disease Interaction: Before taking Metstol 100mg Tablet, let your doctor know if you have anaemia, kidney or liver diseases, diabetes, vitamin deficiency (folate or folic acid), blood disorders like bone marrow suppression and G6PD deficiency, hyperkalaemia or low levels of sodium in the blood, porphyria, and muscle weakness.

• WARFARIN
• HEPARIN
• METHOTREXATE
• REPAGLINIDE
• PROCAINAMIDE
• DIGOXIN
• PYRIMETHAMINE
• DAPSONE
• PHENYTOIN
• RIFAMPICIN
• SPIRONOLACTONE
• AMILORIDE

• Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
• Eating grapefruit during antibiotic treatment can prevent the body from properly utilizing Metstol 100mg Tablet. So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
• Avoid intake of alcoholic beverages with Metstol 100mg Tablet as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Metstol 100mg Tablet in fighting off infections.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Do not walk barefoot at places like gym showers to prevent bacterial infections.

• Renal, hepatic, and blood function tests are advised during prolonged therapy to rule out any toxicity caused by an overdose of Metstol 100mg Tablet. 
• Clostridium difficile-associated diarrhoea (CDAD) is reported during the use of antibiotics like Trimethoprim. Please see your doctor if you experience prolonged diarrhoea.
• Monitor your blood sugar levels regularly since Metstol 100mg Tablet may affect your blood glucose levels if you have diabetes.
• Trimethoprim is moderately removed during dialysis, hence let your doctor know if you are undergoing dialysis treatment so that the dose can be scheduled after the dialysis.

Bacterial infection occurs when harmful bacteria grow in the body and cause illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod, and spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, and tiredness. 

Cystitis is an infection of the urinary tract caused by bacteria. It causes an inflammation of the bladder.