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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Met-Stamlo Capsule is used to treat hypertension (increased blood pressure). It contains Amlodipine and Metoprolol, which widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. It is generally safe to consume. Some people may experience side effects such as nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Met-Stamlo Capsule

Met-Stamlo Capsule belongs to the class of drugs known as antihypertensive, used to treat hypertension (increased blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of stroke and heart attacks.

Met-Stamlo Capsule contains Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker, while Metoprolol belongs to a group of medicines called beta-blockers. Metoprolol relaxes blood vessels by blocking the action of certain natural substances in your body. On the other hand, Amlodipine widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Together, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Met-Stamlo Capsule is prescribed to adults and children more than six years of age.

Met-Stamlo Capsule can be taken with or without food as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it. Met-Stamlo Capsule is preferable to take at the same time every day for better results. Met-Stamlo Capsule is generally safe to consume. Some people may experience nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Most of the side effects of Met-Stamlo Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Don't stop taking $ name without talking to your doctor first. Stopping Met-Stamlo Capsule gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over some time to help prevent these symptoms. It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Met-Stamlo Capsule as it can increase the concentration of Met-Stamlo Capsule and worsen its side effects.

Uses of Met-Stamlo Capsule

Treatment of High blood pressure (hypertension), Heart-related chest pain (angina pectoris)

Directions for Use

Met-Stamlo Capsule can be taken orally with or without food as directed by your physician. Swallow the whole tablet with approximately a glass of water. Do not crush, chew or break it

Medicinal Benefits

Met-Stamlo Capsule is used to treat heart-related conditions like angina (chest pain) and high blood pressure. Amlodipine is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart that relaxes and widens the heart smooth muscles for better blood flow. Metoprolol plays a vital role in relaxing our blood vessels and lowering blood pressure by blocking the action of certain natural substances in your body.  Besides this, Met-Stamlo Capsule help prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements. It improves an individual’s tolerance to physical activity and exercise to keep their blood pressure normal during exercise. As a result, heart rate is at maximum, and exercise does not affect the blood pressure in anyways.

How Met-Stamlo Capsule Works

Met-Stamlo Capsule contains Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker, while Metoprolol belongs to a group of medicines called beta-blockers. Metoprolol relaxes blood vessels by blocking the action of certain natural substances in your body. On the other hand, Amlodipine widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Together, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Met-Stamlo Capsule

  • Oedema (swelling)
  • Dizziness
  • Flushing
  • Palpitation
  • Vertigo
  • Bradycardia (slow heart rate)
  • Headache
  • Feeling exhausted
  • Swollen ankles
  • Flushing
  • Stomach upset
  • Increased levels of potassium in the blood
  • Dry mouth
  • Change in taste
  • Blurred vision
  • Difficulty in breathing
  • Cold fingers or toes

What if I have taken an overdose of Met-Stamlo Capsule

Do not take more than the prescribed dose of Met-Stamlo Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Don't stop taking the medication without talking to your doctor first. Stopping Met-Stamlo Capsule gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Met-Stamlo Capsule can cause low blood sugar (hypoglycaemia). This medication should be used with caution if you have diabetes, particularly if you are taking insulin or other diabetes drugs that may cause low blood sugar. This medication can also induce low blood sugar in babies, children and adults who do not have diabetes. Do not take Met-Stamlo Capsule if you have asthma or similar breathing difficulties. It could make your asthma severe.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipinePhenytoin
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Met-Stamlo Capsule 10's:
Using Met-Stamlo Capsule 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Met-Stamlo Capsule 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Using Met-Stamlo Capsule 10's and phenytoin together may drastically lower Met-Stamlo Capsule 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Met-Stamlo Capsule 10's with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Coadministration of Met-Stamlo Capsule 10's and rifampicin together may lower Met-Stamlo Capsule 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Met-Stamlo Capsule 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Coadministration of lemborexant and Met-Stamlo Capsule 10's may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Met-Stamlo Capsule 10's with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
When Met-Stamlo Capsule 10's is taken with Fosphenytoin, it may decrease the blood levels of Met-Stamlo Capsule 10's, which may make Met-Stamlo Capsule 10's less effective.

How to manage the interaction:
Although taking Met-Stamlo Capsule 10's and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Using a combination of Met-Stamlo Capsule 10's and enzalutamide may drastically lower Met-Stamlo Capsule 10's blood levels, making the medicine less effective.

How to manage the interaction:
Taking Met-Stamlo Capsule 10's with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Coadministration of Met-Stamlo Capsule 10's with itraconazole may significantly raise the blood levels and effects of Met-Stamlo Capsule 10's.

How to manage the interaction:
Met-Stamlo Capsule 10's and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineMitotane
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Using Met-Stamlo Capsule 10's and mitotane together may drastically lower Met-Stamlo Capsule 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Met-Stamlo Capsule 10's with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Coadministration of Ceritinib together with Met-Stamlo Capsule 10's can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Met-Stamlo Capsule 10's with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Met-Stamlo Capsule 10's:
Using Met-Stamlo Capsule 10's and primidone together may lower Met-Stamlo Capsule 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Met-Stamlo Capsule 10's with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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METOPROLOL-50MG+AMLODIPINE-5MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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METOPROLOL-50MG+AMLODIPINE-5MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine and Metoprolol. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease. 

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Met-Stamlo Capsule Substitute

Substitutes safety advice
  • Prolomet AM 50 Tablet 10's

    14.49per tablet
  • Met XL AM 50/5 Tablet 20's

    14.71per tablet
  • Revelol-AM Tablet 15's

    15.45per tablet
  • Amtas-M 50 Tablet 15's

    14.73per tablet
  • Starpress-AM XL 50 Tablet 10's

    19.94per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Met-Stamlo Capsule to avoid unpleasant side-effects.

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Pregnancy

Caution

Met-Stamlo Capsule is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Unsafe

Met-Stamlo Capsule is not recommended while breastfeeding.

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Driving

Unsafe

Met-Stamlo Capsule is unlikely to affect your ability to drive or to operate machinery. However, some people may occasionally feel dizzy or tired when taking Propranolol. If this happens to you, ask your doctor for advice.

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Liver

Caution

Met-Stamlo Capsule to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Met-Stamlo Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Met-Stamlo Capsule in children have not been established. Met-Stamlo Capsule is not recommended in children.

FAQs

Met-Stamlo Capsule is used to treat high blood pressure (hypertension) and heart-related chest pain (angina pectoris). It widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body.
In case, you have missed a dose of Met-Stamlo Capsule , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both doses together. Take only one dose, taking a double dose of Met-Stamlo Capsule will lead to low blood pressure.
When you are taking a beta-blocker, your health care provider may recommend that you limit your consumption of bananas and other high potassium foods including papaya, tomato, avocado and kale.
Met-Stamlo Capsule can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions and one should not abruptly discontinue it without discussing it with a doctor.
Yes, Met-Stamlo Capsule is contraindicated in people with known allergy to any of the components of this medicine. It should be avoided in people with severe kidney or liver impairment and in people with anuria (reduction or absence of urine). It should also be avoided in women who are in the second and third trimesters of their pregnancy.
It's unlikely that Met-Stamlo Capsule affects fertility in men or women. However, there's not enough evidence to say for certain. For the best advice, consult your doctor.
Yes, Met-Stamlo Capsule is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Yes, Met-Stamlo Capsule can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Met-Stamlo Capsule . If you still feel excessively thirsty, please consult your doctor and do as advised for best results of Met-Stamlo Capsule .
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Common side effects of Met-Stamlo Capsule may include nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Most of the side effects of Met-Stamlo Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.
Store in a cool and dry place away from sunlight. Keep out of the sight and reach of children. To help protect the environment, avoid throwing away medicines in wastewater or household waste. Ask your doctor or pharmacist about the disposal of medicines.
In some cases, Met-Stamlo Capsule may cause Headaches. These usually go away after the first week of taking Met-Stamlo Capsule . If they persist, consult your doctor.
Met-Stamlo Capsule is not recommended during pregnancy unless your doctor considers it essential. Consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing it.
Yes, Met-Stamlo Capsule can cause dizziness in some people, particularly when they first start taking it or after taking a higher dose. If this happens to you, do not drive a car, ride a bike, or operate any machinery.
Some persons who use Met-Stamlo Capsule report that their sexual urge decreases or that they are unable to achieve an erection. However, this is not a common side effect, and there is insufficient data to conclude that Met-Stamlo Capsule is the reason. If you're having trouble with your sex life, consult your doctor.
Met-Stamlo Capsule has no effect on hormonal contraception. However, several hormonal methods of contraception, such as the combination pill, progestogen-only pill, and contraceptive patch, are generally not indicated if you have high blood pressure. Consult your doctor if you are taking or utilizing any contraception.
If you take Met-Stamlo Capsule , you do not have to quit doing sports. Regular exercise is beneficial because it reduces blood pressure while also keeping your heart and blood vessels in good working order. If you participate in high-level sports, keep in mind that several sports prohibit the use of metoprolol.
Metoprolol starts working after around 2 hours, but it can take up to a week to reach full effectiveness. You may not notice any difference when you take metoprolol, but it does not mean it is ineffective. It is critical that you continue to take your medication until advised otherwise by your healthcare provider.
Drinking alcohol can increase the risk of side effects with Met-Stamlo Capsule . It can make you feel dizzy or light-headed. It's best to stop drinking alcohol until you see how the medicine affects you.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - MET0287

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