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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Metronil Injection is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Metronil Injection

Metronil Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Metronil Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metronil Injection treats bacterial infections.

Metronil Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Metronil Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may get resolved after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronil Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metronil Injection as it may cause unpleasant side effects.

Uses of Metronil Injection

Treatment of Bacterial infections

Medicinal Benefits

Metronil Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metronil Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metronil Injection treats bacterial infections.

Directions for Use

Metronil Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metronil Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Injection site reactions

Drug Warnings

Do not take Metronil Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronil Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug Interactions

Drug-Drug Interactions: Metronil Injection have interactions with medicines used to treat HIV (amprenavir), anticoagulant medications (anisindione, dicumarol, warfarin), certain vaccinations (BCG, cholera vaccine live, typhoid vaccine live), anti-cancer drug (busulfan) and psychiatry agents (disulfiram).

Drug-Food Interactions: You are recommended not to consume alcohol along with Metronil Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

Drug-Disease Interactions: Inform your doctor if you have kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug-Drug Interactions Checker List

  • AMPRENAVIR
  • ANISINDIONE
  • DICUMAROL
  • WARFARIN
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • BUSULFAN
  • DISULFIRAM

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metronil Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with Metronil Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metronil Injection in fighting off infections.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Generalized symptoms include fever, chills, and fatigue. Bacteria are of various forms comprising spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Metronil Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Metronil Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metronil Injection .

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Driving

Caution

Metronil Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Metronil Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your liver condition.

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Kidney

Caution

Metronil Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your kidney condition.

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Children

Consult your doctor

Limited information about the use of Metronil Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MET1231

Author Details

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FAQs

Metronil Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).
Metronil Injection suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metronil Injection treats bacterial infections.
Caution should be exercised. Metronil Injection may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.
No. Metronil Injection is an antibacterial medicine that acts only against bacterial infections, not viral infections like common cold and flu.
Metronil Injection should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.
Extreme caution should be exercised while using Metronil Injection in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.

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