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  3. Metromeg 500mg Infusion

Metromeg 500mg Infusion, Pack of 1 Infusion
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Metromeg 500mg Infusion is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.

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Composition :

METRONIDAZOLE-500MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Metromeg 500mg Infusion

Metromeg 500mg Infusion belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Metromeg 500mg Infusion contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metromeg 500mg Infusion treats bacterial infections.

Metromeg 500mg Infusion will be administered by a healthcare professional; do not self-administer. Some common side effects of Metromeg 500mg Infusion are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may resolve after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metromeg 500mg Infusion as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metromeg 500mg Infusion as it may cause unpleasant side effects.

Uses of Metromeg 500mg Infusion

Metromeg 500mg Infusion used in the treatment of bacterial infections. The detailed uses of Metromeg 500mg Infusion are as follows:
• Treatment of Infections: Metromeg 500mg Infusion effectively treats various infections, including intra-abdominal, skin, gynecologic, septicemia, bone and joint, CNS, respiratory tract, and endocarditis, by eliminating anaerobic bacteria and parasites, stopping their growth, and alleviating symptoms.
• Surgical Prophylaxis: Metromeg 500mg Infusion is used as a surgical prophylaxis to prevent postoperative infections, particularly for surgeries involving the gastrointestinal tract.
• Management of Clostridium Difficile Infection: Metromeg 500mg Infusion is used to manage severe Clostridium difficile infections, especially when oral medication is not possible.
• Amoebic Dysentery Treatment: Metromeg 500mg Infusion is used to treat amoebic dysentery, a severe intestinal infection caused by the Entamoeba histolytica parasite.
• Combination Therapy: Metromeg 500mg Infusion is often used in combination with other antibiotics to treat serious infections, offering a broad spectrum of action and enhancing treatment effectiveness.

Directions for Use

Metromeg 500mg Infusion will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Metromeg 500mg Infusion belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metromeg 500mg Infusion contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby, Metromeg 500mg Infusion treats bacterial infections.

How Metromeg 500mg Infusion Works

Metromeg 500mg Infusion contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metromeg 500mg Infusion treats bacterial infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Metromeg 500mg Infusion
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
  • Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
  • Establish a daily routine to maintain independence and organization.
  • Consider learning Braille or using assistive technologies to enhance daily life.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Metromeg 500mg Infusion

A health care professional administers Metromeg 500mg Infusion in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include nausea, vomiting, loss of muscle coordination, numbness, pain, burning, or tingling in your hands or feet, and seizures. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Metromeg 500mg Infusion if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metromeg 500mg Infusion as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
MetronidazoleDisulfiram
Critical

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
How does the drug interact with Metromeg 500mg Infusion:
Co-administration of Amprenavir with Metromeg 500mg Infusion can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metromeg 500mg Infusion with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Metromeg 500mg Infusion:
Coadministration of Disulfiram with Metromeg 500mg Infusion can increase the risk of side effects.

How to manage the interaction:
Taking Metromeg 500mg Infusion and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Metromeg 500mg Infusion:
Drinking alcohol while taking Metromeg 500mg Infusion can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metromeg 500mg Infusion with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleMebendazole
Severe
How does the drug interact with Metromeg 500mg Infusion:
Coadministration of Metromeg 500mg Infusion with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metromeg 500mg Infusion and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Metromeg 500mg Infusion:
Coadministration of Metromeg 500mg Infusion with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metromeg 500mg Infusion and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Metromeg 500mg Infusion:
Coadministration of Busulfan and Metromeg 500mg Infusion may increase the risk of side effects.

How to manage the interaction:
Taking Metromeg 500mg Infusion and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleFluconazole
Moderate
How does the drug interact with Metromeg 500mg Infusion:
Co-administration of Fluconazole together with Metromeg 500mg Infusion can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metromeg 500mg Infusion with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metromeg 500mg Infusion to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet. This food can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should also be included in the diet.
  • Avoid intake of alcoholic beverages with Metromeg 500mg Infusion as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metromeg 500mg Infusion in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Metromeg 500mg Infusion Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Metromeg 500mg Infusion to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Metromeg 500mg Infusion should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metromeg 500mg Infusion.

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Driving

Caution

Metromeg 500mg Infusion may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Metromeg 500mg Infusion to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Metromeg 500mg Infusion to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Consult your doctor

Limited information about the use of Metromeg 500mg Infusion in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

Have a query?

FAQs

Metromeg 500mg Infusion belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).

Metromeg 500mg Infusion suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.

Caution should be exercised. Metromeg 500mg Infusion may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.

No. Metromeg 500mg Infusion is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.

Metromeg 500mg Infusion should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.

Extreme caution should be exercised while using Metromeg 500mg Infusion in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.

Country of origin

India
Other Info - ME59552

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

May 2, 2025 | 12:51 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&type=display
  2. https://www.medicines.org.uk/emc/files/pil.13293.pdf
  3. https://www.medicines.org.uk/emc/product/1842/smpc#gref
  4. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  5. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3
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