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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Metrogyl Injection is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.
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PARENTERAL

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Expires on or after :

Jan-27

Metrogyl Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Metrogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.

Metrogyl Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Metrogyl Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may get resolved after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metrogyl Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metrogyl Injection as it may cause unpleasant side effects.

Treatment of Bacterial infections
Metrogyl Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Metrogyl Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metrogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.

Metrogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.
Store in a cool and dry place away from sunlight
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Injection site reactions
Metrogyl Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include nausea, vomiting, loss of muscle coordination, numbness, pain, burning, or tingling in your hands or feet, and seizures. Your doctor may take necessary measures if an overdose is suspected.

Do not take Metrogyl Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metrogyl Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

verifiedApollotooltip
MetronidazoleDisulfiram
Critical
MetronidazoleAmprenavir
Critical

Drug-Drug Interactions

MetronidazoleDisulfiram
Critical
How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Disulfiram with Metrogyl Injection 100 ml can increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Metrogyl Injection 100 ml:
Co-administration of Amprenavir with Metrogyl Injection 100 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Metrogyl Injection 100 ml:
Drinking alcohol while taking Metrogyl Injection 100 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleMebendazole
Severe
How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Metrogyl Injection 100 ml with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metrogyl Injection 100 ml and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Metrogyl Injection 100 ml with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metrogyl Injection 100 ml and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Busulfan and Metrogyl Injection 100 ml may increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleFluconazole
Moderate
How does the drug interact with Metrogyl Injection 100 ml:
Co-administration of Fluconazole together with Metrogyl Injection 100 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metrogyl Injection 100 ml with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • It would be best to take probiotics after taking the full course of Metrogyl Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with Metrogyl Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metrogyl Injection in fighting off infections.
No
ANTIBIOTICS
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Unsafe

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Caution

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Caution

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Caution

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Caution

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Caution

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Consult your doctor

FAQs

Metrogyl Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).
Metrogyl Injection suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.
Caution should be exercised. Metrogyl Injection may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.
No. Metrogyl Injection is an antibacterial medicine that acts only against bacterial infections, not viral infections like common cold and flu.
Metrogyl Injection should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.
Extreme caution should be exercised while using Metrogyl Injection in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.
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