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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). It contains S-amlodipine and S-metoprolol which work by relaxing and widening the blood vessels, improving the blood flow, and making the heart beat slowly and with less force. In some cases, this medicine may cause side effects such as stomach pain, tiredness, dizziness, slow heart rate, nausea, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym :

S AMLODIPINE+S METOPROLOL SUCCINATE

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Metpure AM 2.5 Tablet

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). Also, Metpure AM 2.5 Tablet is used to treat chest pain and irregular heart rhythm. Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Metpure AM 2.5 Tablet is a combination of two drugs:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class, which works by blocking beta receptors in the heart and making the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

Take Metpure AM 2.5 Tablet as prescribed by your doctor. You are advised to take Metpure AM 2.5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention. Most of these side effects of Metpure AM 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert, as Metpure AM 2.5 Tablet may cause dizziness or tiredness. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Metpure AM 2.5 Tablet is used with caution in heart failure, during surgeries, pheochromocytoma, lung diseases, diabetes, peripheral vascular disease, hyperthyroidism, and aortic stenosis. Metpure AM 2.5 Tablet is not recommended in cardiogenic shock, hyperlipidemia, glaucoma, or liver diseases.

Uses of Metpure AM 2.5 Tablet

Treatment of Hypertension (high blood pressure), angina (chest pain)

Directions for Use

Take Metpure AM 2.5 Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Metpure AM 2.5 Tablet contains S-amlodipine and S-metoprolol, which are primarily used to treat high blood pressure. S-amlodipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to beta-blockers that block beta receptors in the heart and make the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

How Metpure AM 2.5 Tablet Works

Metpure AM 2.5 Tablet is a combination of two drugs:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class, which works by blocking beta receptors in the heart and making the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metpure AM 2.5 Tablet

  • Tiredness

  •  Dizziness

  •  Slow heart rate

  •  Nausea

  •  Headache

  •  Orthostatic hypotension (low blood pressure when standing up from sitting or lying position)

  •  Depression

  •  Stomach pain

  •  Fluid retention

What if I have taken an overdose of Metpure AM 2.5 Tablet

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Complete the full course of medication and do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Avoid taking Metpure AM 2.5 Tablet if you have blood circulation or heart problems, Prinzmetal’s angina (painful feeling in the chest in periods of rest), asthma, chronic obstructive pulmonary disease (COPD), breathing problems, phaeochromocytoma (tumor in the adrenal gland), low blood pressure, diabetes or metabolic acidosis (increased acidity of the blood), hyperthyroidism. Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert as Metpure AM 2.5 Tablet may cause dizziness or tiredness. If you are about to under any surgery or receive anesthetics, please inform your doctor or dentist that you are taking Metpure AM 2.5 Tablet as it may cause a very slow heartbeat.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
MetoprololElvitegravir
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Using Metpure AM 2.5 Tablet 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Metpure AM 2.5 Tablet 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Taking elvitegravir may increase the metabolism of Metpure AM 2.5 Tablet 10's.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet 10's can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololArtemether
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Both Metpure AM 2.5 Tablet 10's and Artemether may increase the blood levels and effects of Metpure AM 2.5 Tablet 10's activity.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet 10's and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololTizanidine
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Coadministration of Metpure AM 2.5 Tablet 10's and Tizanidine may reduce the efficiency of Metpure AM 2.5 Tablet 10's.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet 10's and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololVerapamil
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Coadministration of Metpure AM 2.5 Tablet 10's with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet 10's can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololDiltiazem
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Coadministration of Metpure AM 2.5 Tablet 10's with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Metpure AM 2.5 Tablet 10's and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololClonidine
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Co-administration of Clonidine and Metpure AM 2.5 Tablet 10's may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure AM 2.5 Tablet 10's, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Combine use of Metpure AM 2.5 Tablet 10's with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet 10's can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololAminophylline
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Coadministration of Aminophylline with Metpure AM 2.5 Tablet 10's together can make Metpure AM 2.5 Tablet 10's less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metpure AM 2.5 Tablet 10's may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololAtazanavir
Severe
How does the drug interact with Metpure AM 2.5 Tablet 10's:
Use of Metpure AM 2.5 Tablet 10's with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metpure AM 2.5 Tablet 10's and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine and Metoprolol. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, which may lower high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Metpure AM 2.5 Tablet Substitute

Substitutes safety advice
  • Eslomet 2.5 Tablet 10's

    13.82per tablet
  • STARCAD SA 2.5MG TABLET

    7.65per tablet
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Alcohol

Unsafe

Avoid alcohol consumption with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

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Pregnancy

Caution

Metpure AM 2.5 Tablet is a category C pregnancy drug. Metpure AM 2.5 Tablet is given to pregnant women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Metpure AM 2.5 Tablet may be excreted in human milk in small amounts. Therefore, Metpure AM 2.5 Tablet is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Metpure AM 2.5 Tablet may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Metpure AM 2.5 Tablet .

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Liver

Caution

Metpure AM 2.5 Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Metpure AM 2.5 Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

It is not recommended for children as the safety and effectiveness were not established.

FAQs

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). It is also used to treat chest pain and irregular heart rhythm.
Metpure AM 2.5 Tablet is a combination of two drugs, namely: S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class that works by blocking beta receptors in the heart and makes the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together they lower high blood pressure.
Metpure AM 2.5 Tablet cause common side effects like tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention.
Metpure AM 2.5 Tablet should be used with caution in diabetic patients as it may increase the risk of severe low blood sugar levels. Therefore, if you have diabetes, inform your doctor before taking Metpure AM 2.5 Tablet . Also, regular monitoring of blood sugar levels is recommended while taking Metpure AM 2.5 Tablet .
Metpure AM 2.5 Tablet may cause dizziness when standing up from sitting or lying position suddenly. Therefore, to avoid such effects, it is advised to stand up slowly from sitting or lying position.
Metpure AM 2.5 Tablet may cause high potassium levels in the blood and cause adverse effects on overdose. Therefore, take Metpure AM 2.5 Tablet only in doses as prescribed by your doctor.
Metpure AM 2.5 Tablet is may be safe to use in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition.
Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MET0126

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