Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). Also, Metpure AM 2.5 Tablet is used to treat chest pain and irregular heart rhythm. Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Metpure AM 2.5 Tablet is a combination of two drugs:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class, which works by blocking beta receptors in the heart and making the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

Take Metpure AM 2.5 Tablet as prescribed by your doctor. You are advised to take Metpure AM 2.5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention. Most of these side effects of Metpure AM 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert, as Metpure AM 2.5 Tablet may cause dizziness or tiredness. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Metpure AM 2.5 Tablet is used with caution in heart failure, during surgeries, pheochromocytoma, lung diseases, diabetes, peripheral vascular disease, hyperthyroidism, and aortic stenosis. Metpure AM 2.5 Tablet is not recommended in cardiogenic shock, hyperlipidemia, glaucoma, or liver diseases.

Metpure AM 2.5 Tablet contains S-amlodipine and S-metoprolol, which are primarily used to treat high blood pressure. S-amlodipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to beta-blockers that block beta receptors in the heart and make the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

• Tiredness

•  Dizziness

•  Slow heart rate

•  Nausea

•  Headache

•  Orthostatic hypotension (low blood pressure when standing up from sitting or lying position)

•  Depression

•  Stomach pain

•  Fluid retention

If you are known to be allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Complete the full course of medication and do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Avoid taking Metpure AM 2.5 Tablet if you have blood circulation or heart problems, Prinzmetal’s angina (painful feeling in the chest in periods of rest), asthma, chronic obstructive pulmonary disease (COPD), breathing problems, phaeochromocytoma (tumor in the adrenal gland), low blood pressure, diabetes or metabolic acidosis (increased acidity of the blood), hyperthyroidism. Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert as Metpure AM 2.5 Tablet may cause dizziness or tiredness. If you are about to under any surgery or receive anesthetics, please inform your doctor or dentist that you are taking Metpure AM 2.5 Tablet as it may cause a very slow heartbeat.

Drug-Drug Interaction: Metpure AM 2.5 Tablet may have interaction with pain killers (aspirin), antidepressants (duloxetine, nefazodone), water tablets (furosemide), anticonvulsants (phenytoin, phenobarbital, carbamazepine), medicines used to lower high blood pressure (verapamil,  diltiazem, nifedipine, disopyramide), drugs to treat irregular heartbeat (quinidine, amiodarone, propafenone), antidiabetic drug (insulin glargine), thyroid medicines (levothyroxine), benzodiazepine (alprazolam), blood thinner (apixaban), lower high cholesterol-lowering medicines (atorvastatin).

Drug- Food Interaction: Metpure AM 2.5 Tablet may interact with grapefruit or grapefruit juice as it may increase the risk of severe low blood pressure. Metpure AM 2.5 Tablet may interact with St. John’s wort (herbal supplement used to treat depression). Also, avoid alcohol consumption as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

Drug-Disease Interaction: Avoid taking Metpure AM 2.5 Tablet if you have blood circulation or heart problems, Prinzmetal’s angina (painful feeling in the chest during periods of rest), asthma, chronic obstructive pulmonary disease (COPD), breathing problems, phaeochromocytoma (tumor in the adrenal gland), low blood pressure, diabetes or metabolic acidosis (increased acidity of the blood). If you have a slow heart rate, psoriasis (severe skin rashes), myasthenia gravis (muscle weakness), dry eyes, hyperthyroidism, diabetes, kidney, liver, or heart problems, inform your doctor before taking Metpure AM 2.5 Tablet .

• ASPIRIN
• DULOXETINE
• NEFAZODONE
• FUROSEMIDE
• PHENYTOIN
• PHENOBARBITAL
• CARBAMAZEPINE
• VERAMAPIL
• DILTIAZEM
• NIFEDIPINE
• DISOPYRAMIDE
• QUINIDINE
• AMIODARONE
• PROPAFENONE
• INSULIN GLARGINE
• LEVOTHYROXINE
• ALPRAZOLAM
• APIXABAN
• ATORVASTATIN

• Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
• Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
• Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
• Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
• Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, which may lower high blood pressure.
• Quit smoking and avoid the consumption of alcohol.

• Regular monitoring of blood pressure is recommended while taking Metpure AM 2.5 Tablet .

• Metpure AM 2.5 Tablet may rarely cause changes in blood tests and liver function tests.

• A low salt diet and regular exercise are recommended along with Metpure AM 2.5 Tablet for effective results.

• Your doctor may advise regular blood tests for monitoring of electrolytes.

Blood pressure/Hypertension: Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.