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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Methyzone Tablet is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. It contains Pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, helps in proper muscle functioning and prevents muscle weakness. In some cases, you may experience common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition :

PYRIDOSTIGMINE-60MG

Manufacturer/Marketer :

First Horizon Pharma

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Methyzone Tablet

Methyzone Tablet is used to treat myasthenia gravis (muscle weakness). Besides this, Methyzone Tablet also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. Myasthenia gravis is a long-term neuromuscular disease that leads to musculoskeletal weakness caused by excess activity of a protein (cholinesterase protein).

Methyzone Tablet contains ‘Pyridostigmine’, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in proper muscle functioning and prevents muscle weakness. 

Take Methyzone Tablet 30-60 minutes before food. Swallow Methyzone Tablet as a whole; do not crush or chew the tablet. You are advised to take Methyzone Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Methyzone Tablet if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, or kidney problems. Consult your doctor before taking Methyzone Tablet if you are pregnant before taking Methyzone Tablet if you are pregnant or breastfeeding. Methyzone Tablet may cause dizziness and vision problems, so drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness. Methyzone Tablet can be given to children if prescribed by the doctor; the dose depends upon the child’s age. Keep your doctor informed about your health condition and medicines you are taking to rule out unpleasant side effects.

Uses of Methyzone Tablet

Treatment of Myasthenia gravis (muscle weakness)

Medicinal Benefits

Methyzone Tablet belongs to the group of medicines called cholinesterase inhibitors used to treat myasthenia gravis (muscle weakness). Methyzone Tablet works by stopping the excessive activity of cholinesterase, thus helping the muscles to work properly. Additionally, Methyzone Tablet is also used to treat paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to soman nerve agent poisoning. Methyzone Tablet affects the chemicals in the body which are involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in treating myasthenia gravis.

Side Effects of Methyzone Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Increased salivation (drooling)
  • Sweating, cough with mucus
  • Rash
  • Muscle cramps
  • Blurred vision

Directions for Use

Take Methyzone Tablet 30-60 minutes before food. Swallow Methyzone Tablet as a whole; do not crush or chew the tablet. The dose and duration of Methyzone Tablet can vary depending upon your condition. Your doctor will decide the dose and frequency of the medicine you will take.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Methyzone Tablet if you are allergic to any of its contents; if you are constipated or cannot urinate unless prescribed by the doctor. Inform your doctor before taking Methyzone Tablet if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, kidney problems, vagotonia (overactive vagus nerves), overactive thyroid; if you have had surgery to remove thymus gland or if you due to have any surgery. Consult your doctor before taking Methyzone Tablet if you are pregnant before taking Methyzone Tablet if you are pregnant or breastfeeding. Methyzone Tablet may cause dizziness and vision problems; so, drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness. 

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS

Drug-Drug Interactions

verifiedApollotooltip
MecobalaminNeomycin
Moderate
MecobalaminChloramphenicol
Moderate

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a healthy weight. Include vegetables, fruits and grains in your diet.
  • Diet low in fat, saturated fat and cholesterol would be helpful.
  • Use salt and sugars in moderation.
  • Avoid consumption of alcohol.
  • Avoid processed and fried foods.
  • Try eating soft, mashed, or pureed foods as they are easy to swallow.
  • Avoid dry, chunky and chewy foods.
  • Regularly sip water during meals and snacks as it helps to moisten and soften the food. 
  • Add thickening agents to liquid foods as liquid foods may get into the lungs and cause choking.
  • Be careful while swallowing foods and liquids.

Habit Forming

No

How Methyzone Tablet Works

Methyzone Tablet contains pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in proper muscle functioning and prevents muscle weakness.

What if I have taken an overdose of Methyzone Tablet

Do not take more than the prescribed dose of Methyzone Tablet as it may cause overdose. The symptoms of overdose include stomach cramps, sweating, nausea, vomiting, diarrhea, blurred vision, drooling, and weak or shallow breathing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Methyzone Tablet belongs to the pregnancy category C. Please consult your doctor before taking Methyzone Tablet if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Small amounts of Methyzone Tablet may pass into breastmilk. Please consult your doctor before taking Methyzone Tablet if you are breastfeeding.

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Driving

Unsafe

Methyzone Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Methyzone Tablet if you have liver impairment/liver disease before taking Methyzone Tablet .

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Methyzone Tablet .

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Children

Unsafe

Not recommended for use in anyone less than 18 years of age

Country of origin

India

Manufacturer/Marketer address

A 102, VAIBHAV BLDG., JAI VAIBHAV C.H.S. JAMLI GALLI, BORIVALI (W), MUMBAI-400 092
Other Info - MET0419

Author Details

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FAQs

Methyzone Tablet is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve-poisoning gas.
Methyzone Tablet works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in proper muscle functioning and prevents muscle weakness.
Methyzone Tablet is used as prophylaxis against the lethal effects of soman nerve agent poisoning especially by military. It is intended to be used in conjunction with atropine and pralidoxime therapy and protective garments and gas-mask.
Do not stop taking Methyzone Tablet on your own. To treat your condition effectually continue taking Methyzone Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Methyzone Tablet .
Caution is needed in patients with asthma, breathing difficulty, wheezing and chronic cough as Methyzone Tablet may worsen the condition. Please consult your doctor before taking Methyzone Tablet if you have asthma or any breathing problems.
Talk to your doctor before taking Methyzone Tablet if you have hypertension (high blood pressure) as it may cause insignificant changes such as elevated blood pressure.
Anticholinergic drugs are often used in the treatment of glaucoma. Methyzone Tablet is a cholinergic inhibitor, and its use in patients with glaucoma may cause additive effects which could lead to night vision problems. Please consult your doctor before taking Methyzone Tablet if you have glaucoma.
Methyzone Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, muscle cramps, blurred vision, rash and increased salivation. If these side effects persist or worsen, please consult your doctor.
Methyzone Tablet does not cause high blood pressure. In fact, intake of high dose of Methyzone Tablet can cause low blood pressure.
No, Methyzone Tablet should not be crushed or chewed. It should be taken as a whole with water.
Methyzone Tablet does not cause increase in heartbeats. On the other hand, it can be used in the treatment of increase in heartbeats in postural orthostatic tachycardia syndrome (POTS) where there is an abnormal increase in the heartbeats while standing from a lying position.
Methyzone Tablet should not be cut in half unless your doctor tells you to take a half tablet and it has a score mark on it. It should not be chewed or crushed before taking.
Methyzone Tablet does not cure myasthenia gravis but relieves the symptoms of it by reducing and improving muscle weakness. The duration for which you must take Methyzone Tablet will depend on your needs. Do not stop taking Methyzone Tablet until and unless advised by your doctor, even if you start feeling better.
A very small amount of Methyzone Tablet may pass into breast milk, which may or may not affect your baby. Please take your doctor’s advice before taking Methyzone Tablet if you are breastfeeding.
No, do not take Methyzone Tablet for constipation. It is used only when constipation occurs due to intestinal paralysis and strictly on prescription by the doctor.
Methyzone Tablet should not be taken by patients who are allergic to it, who have constipation or difficulty urinating, unless the doctor has advised to use this medicine.
If you have accidentally taken more than the required dose, seek medical help immediately. An overdose of Methyzone Tablet may cause nausea, vomiting, stomach pain, diarrhea, salivation, excessive sweating, blurred vision, difficulty in breathing, excessive weakness, and even paralysis.
No, Methyzone Tablet is not a steroid. It belongs to the group of medicines called anticholinesterases.
No, there is no proof that Methyzone Tablet has abuse potential.
No, Methyzone Tablet does not cause weight gain. However, if you gain weight, it may be due to inactivity related to muscle weakness in myasthenia gravis.
Yes, Methyzone Tablet is safe if used as advised by the doctor. Do not exceed the recommended dose.
Methyzone Tablet may cause blurred vision. Thus, you should avoid driving until you know how Methyzone Tablet affects you.

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