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Composition :
METHOTREXATE-500MG/20ML
Manufacturer/Marketer :
Getwell Oncology Pvt Ltd
Consume Type :
PARENTERAL
Return Policy :
3 Days Returnable
Expires on or after :
Jan-27
Drug-Drug Interactions
MethotrexateEtretinate
Critical
MethotrexateRabeprazole
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Methotex 500 mg Injection 20 ml:
Co-administration of Etretinate with Methotex 500 mg Injection 20 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methotex 500 mg Injection 20 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Methotex 500 mg Injection 20 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methotex 500 mg Injection 20 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexateRabeprazole
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Co-administration of Methotex 500 mg Injection 20 ml with Rabeprazole can increase the blood levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between Rabeprazole and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Methotex 500 mg Injection 20 ml with Rabeprazole can increase the blood levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between Rabeprazole and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateProcaine benzylpenicillin
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Coadministration of Methotex 500 mg Injection 20 ml with procaine benzyl penicillin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between procaine benzyl penicillin and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms, consult your doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Methotex 500 mg Injection 20 ml with procaine benzyl penicillin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between procaine benzyl penicillin and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms, consult your doctor. Do not stop using any medications without consulting to a doctor.
MethotrexateMefenamic acid
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Coadministration of Mefenamic acid with Methotex 500 mg Injection 20 ml may increase the blood levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between mefenamic acid and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of Mefenamic acid with Methotex 500 mg Injection 20 ml may increase the blood levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between mefenamic acid and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateEverolimus
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Coadministration of Everolimus with Methotex 500 mg Injection 20 ml can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Methotex 500 mg Injection 20 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Everolimus with Methotex 500 mg Injection 20 ml can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Methotex 500 mg Injection 20 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
MethotrexateIndometacin
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Co-administration of Methotex 500 mg Injection 20 ml with Indomethacin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 500 mg Injection 20 ml and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Methotex 500 mg Injection 20 ml with Indomethacin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 500 mg Injection 20 ml and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateAspirin
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Co-administration of Methotex 500 mg Injection 20 ml with aspirin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between aspirin and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience symptoms such as nausea, vomiting, diarrhea, sore throat, chills, fever, rash, unusual bruising or bleeding, pale skin, dark urine, swelling of the legs and hands, breathing difficulty. Do not stop using any medications without consulting a doctor.
Co-administration of Methotex 500 mg Injection 20 ml with aspirin can increase the levels and side effects of Methotex 500 mg Injection 20 ml.
How to manage the interaction:
Although there is a possible interaction between aspirin and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience symptoms such as nausea, vomiting, diarrhea, sore throat, chills, fever, rash, unusual bruising or bleeding, pale skin, dark urine, swelling of the legs and hands, breathing difficulty. Do not stop using any medications without consulting a doctor.
MethotrexateTofacitinib
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Coadministration of Methotex 500 mg Injection 20 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Methotex 500 mg Injection 20 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
MethotrexateOmeprazole
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Coadministration of omeprazole with Methotex 500 mg Injection 20 ml may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of omeprazole with Methotex 500 mg Injection 20 ml may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Methotex 500 mg Injection 20 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
MethotrexateDicloxacillin
Severe
How does the drug interact with Methotex 500 mg Injection 20 ml:
Co-administration of Methotex 500 mg Injection 20 ml with dicloxacillin can increase the levels and effects of Methotex 500 mg Injection 20 ml. This can increase the risk or severity of serious infections.
How to manage the interaction:
Although there is a possible interaction between Methotex 500 mg Injection 20 ml and dicloxacillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Methotex 500 mg Injection 20 ml with dicloxacillin can increase the levels and effects of Methotex 500 mg Injection 20 ml. This can increase the risk or severity of serious infections.
How to manage the interaction:
Although there is a possible interaction between Methotex 500 mg Injection 20 ml and dicloxacillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Methotex 500 mg Injection.
Pregnancy
Unsafe
Methotex 500 mg Injection may cause serious birth defects. It is not recommended to take Methotex 500 mg Injection while you are pregnant.
Breast Feeding
Unsafe
Methotex 500 mg Injection passes into breast milk. Avoid breastfeeding whilst on treatment with Methotex 500 mg Injection and for at least 1 week after the last dose.
Driving
Caution
Methotex 500 mg Injection may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Methotex 500 mg Injection affects you.
Liver
Caution
Please consult your doctor if you have liver impairment before taking Methotex 500 mg Injection.
Kidney
Caution
Please consult your doctor if you have kidney impairment before taking Methotex 500 mg Injection.
Children
Caution
The efficacy and safety of Methotex 500 mg Injection in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Methotex 500 mg Injection in children.
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