Methofine 20mg Tablet belongs to the class of medicines called psoralens primarily used to treat psoriasis (scaly, itchy, and red patches on the skin), or vitiligo (discoloured patches in different areas of the body, including the skin, hair). Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. Psoriasis can also be caused by internal and external activates, including sunburn, mild trauma, systemic drugs, infections, and stress. Vitiligo is a disorder in which the skin turns white due to the loss of pigment from the melanocytes, (cells that produce the colour), melanin that gives skin colour. 

Methofine 20mg Tablet contains methoxsalen, that is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.

Take Methofine 20mg Tablet as prescribed by your doctor. You are advised to take Methofine 20mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience erythema (skin redness), oedema (swelling), blisters on the skin, and itching. Most of these side effects of Methofine 20mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Methofine 20mg Tablet, please inform your doctor if you have any allergies, history of skin cancer, eye disorder, heart disease, liver disease, kidney disease, or skin pigment disorder. Immediately contact your doctor if you are pregnant or plan to become pregnant, and breastfeeding.

Methofine 20mg Tablet contains methoxsalen, which is a local acting drug. It is primarily used in the treatment of psoriasis (scaly, itchy, and red patches on the skin), or vitiligo (discoloured patches in different areas of the body, including the skin, hair). Methofine 20mg Tablet is an organic compound and a local acting drug. It is used alongside ultraviolet-A radiation. It works by reducing the number of cells the skin makes.

• Erythema (skin redness)
• Oedema (swelling)
• Blisters on the skin
• Itching

Inform your doctor before using Methofine 20mg Tablet, if you have previously had an allergic reaction (hypersensitivity). Before starting Methofine 20mg Tablet, please inform your doctor if you have any history of skin cancer, eye disorder, heart disease, liver disease, kidney disease, or skin pigment disorder. Immediately contact your doctor if you are pregnant or plan to become pregnant, and breastfeeding. If there is an overdose, you may be trained to stay in a dark room for 24 hours and make yourself vomit.

Drug-Drug Interactions: Methofine 20mg Tablet may interact with antibiotics (sulfamethoxazole, ciprofloxacin), diuretics (hydrochlorothiazide), antiviral (lopinavir, ritonavir), medicines used for lowering the level of cholesterol (rosuvastatin).

Drug-Food Interactions: Avoid eating or arriving in contact with limes, figs, mustard, and carrots.

Drug-Disease Interactions: Methofine 20mg Tablet should be used with caution in patients with liver disease, skin cancer, heart disease, sunburn, and aphakia (absence of lens in eyes).

• CIPROFLOXACIN
• HYDROCHLOROTHIAZIDE
• LOPINAVIR
• RITONAVIR

• Avoid sunlight exposure for 24 hours before taking Methofine 20mg Tablet. Wear UVA-absorbing, and cover exposed skin, wrap-around sunglasses, or use sunblock for the twenty-four-hour period after treatment with Methofine 20mg Tablet.

• Use extra caution for at least 48 hours after each treatment. Cover your skin for at least 8 hours by wearing protective clothing after each treatment, 

• Do not increase the quantity of Methofine 20mg Tablet if you are taking or use additional time under an ultraviolet lamp or in the sunlight.

• You will need to have an eye check-up before starting Methofine 20mg Tablet and also once a year afterwards.
• Avoid sunlight on your lips or skin for at least 8 hours after taking Methofine 20mg Tablet.

Psoriasis: It is a chronic, painful, nontransmissible, deactivating, and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriasis can also be caused by internal and external activates, including sunburn, mild trauma, systemic drugs, infections, and stress. Psoriasis involves the nails and skin and is related to a number of comorbidities. Skin wounds are generalized or localized, mostly balanced, red pimples and plaques, sharply established, and usually covered with silver or white scales. Injuries cause harshness, itching, and pain.

Vitiligo: It is a disorder in which the skin turns white due to the loss of pigment from the melanocytes, (cells that produce the colour), melanin that gives the colour of skin. The hair that develops in regions affected by vitiligo may also turn white. People with vitiligo must protect their skin from contact with the sun.