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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Met XL R 25/2.5 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. It is a combination medicine which suppress the contraction of blood vessels and promote smooth blood flow. It also alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include headache, nausea, dizziness, stomach upset, and weakness.

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Synonym :

METOPROLOL SUCCINATE+RAMIPRIL

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Met XL R 25/2.5 Tablet

Met XL R 25/2.5 Tablet belongs to the 'anti-hypertensive drugs' class, primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Met XL R 25/2.5 Tablet is composed of Metoprolol and Ramipril. Metoprolol is a beta-blocker, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Ramipril is an angiotensin-converting enzyme inhibitor, which relaxes and widens the blood vessels making it easier for the heart to pump blood to all body parts. Hence, it reduces the chance of having a heart attack, stroke, heart-related chest pain (angina) or other cardiovascular diseases.

You can take Met XL R 25/2.5 Tablet with food or without food. Swallow it as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you need to take Met XL R 25/2.5 Tablet based on your medical condition. In some cases, you may experience certain common side-effects like tiredness, dizziness, shortness of breath, bradycardia, hypotension, diarrhoea, headache, and rash. Most of these side effects do not require medical attention and will resolve gradually over time. Talk to your doctor if you experience these side effects persistently.

Try not to stop taking this medicine on your own even if your blood pressure is normal as it may worsen your condition. Let your doctor know if you have any liver, kidney or heart problems, are pregnant or breastfeeding. Do not take Met XL R 25/2.5 Tablet if you are hypersensitive to metoprolol, ramipril, any beta-blocker, any other ACE inhibitor, or any of the excipients of Met XL R 25/2.5 Tablet . Met XL R 25/2.5 Tablet may cause dizziness, so drive with caution. Avoid alcohol consumption along with Met XL R 25/2.5 Tablet as it might lead to increased dizziness or unpleasant side effects.

Uses of Met XL R 25/2.5 Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it

Medicinal Benefits

Met XL R 25/2.5 Tablet is a combination of two blood pressure-lowering medications, metoprolol and ramipril. Metoprolol is a beta-blocker that works by decreasing the heart rate and increasing the heart's efficiency in pumping blood throughout the body. Ramipril is an ACE inhibitor that relaxes blood vessels and decreases stress on the heart, allowing blood to flow more easily. Thereby, Met XL R 25/2.5 Tablet helps treat hypertension and thus reduces the chance of having a heart attack, stroke, heart-related chest pain (angina) or other cardiovascular diseases.

How Met XL R 25/2.5 Tablet Works

Met XL R 25/2.5 Tablet is composed of Metoprolol and Ramipril. Metoprolol is a beta-blocker, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Ramipril is an angiotensin-converting enzyme inhibitor, which relaxes and widens the blood vessels making it easier for the heart to pump blood to all body parts. Hence, it reduces the chance of having a heart attack, stroke, heart-related chest pain (angina) or other cardiovascular diseases.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Met XL R 25/2.5 Tablet

  • Headache
  • Dizziness or light-headedness
  • Cough
  • Digestive disturbances
  • Abdominal discomfort
  • Dyspepsia
  • Diarrhoea
  • Nausea
  • Vomiting

What if I have taken an overdose of Met XL R 25/2.5 Tablet

Do not take more than the prescribed dose of Met XL R 25/2.5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Try not to stop taking this medicine on your own even if your blood pressure is normal as it may worsen your condition. Do not take Met XL R 25/2.5 Tablet if you are hypersensitive to metoprolol, ramipril, any beta-blocker, any other ACE inhibitor, or any of the excipients of Met XL R 25/2.5 Tablet . Inform your doctor if you have angioedema (swelling under the skin),  diabetes, moderate to severe renal impairment, diabetic nephropathy, severe bradycardia, second or third-degree heart block, cardiogenic shock, cardiac failure, sick sinus syndrome, or liver problems. Met XL R 25/2.5 Tablet is not advised to be used during pregnancy or breastfeeding. Met XL R 25/2.5 Tablet is not recommended for children because its safety and efficacy have not been proven. Met XL R 25/2.5 Tablet may cause dizziness, so drive carefully. Inform your doctor if you take any other prescription or non-prescription medications or herbal supplements to rule out any potential side effects or drug interactions.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
RamiprilSpironolactone
Severe

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking aliskiren together with Met XL R 25/2.5 Tablet 15's may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Met XL R 25/2.5 Tablet 15's with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
RamiprilSpironolactone
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Using Met XL R 25/2.5 Tablet 15's together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
RamiprilPotassium iodide
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Potassium Iodide with Met XL R 25/2.5 Tablet 15's may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Potassium iodide and Met XL R 25/2.5 Tablet 15's, you can take these medicines together if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilEprosartan
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Coadministration of Met XL R 25/2.5 Tablet 15's together with eprosartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Met XL R 25/2.5 Tablet 15's together with Eprosartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
RamiprilValsartan
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Met XL R 25/2.5 Tablet 15's with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Met XL R 25/2.5 Tablet 15's together with Valsartan can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting a doctor.
RamiprilIrbesartan
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Met XL R 25/2.5 Tablet 15's together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Met XL R 25/2.5 Tablet 15's together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
RamiprilOlmesartan medoxomil
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Met XL R 25/2.5 Tablet 15's together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking olmesartan medoxomil with Met XL R 25/2.5 Tablet 15's may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
RamiprilPotassium acetate
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Met XL R 25/2.5 Tablet 15's with potassium acetate may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm

How to manage the interaction:
Although there is a interaction between Met XL R 25/2.5 Tablet 15's and Potassium acetate, but it can be taken if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilKetoconazole
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Coadministration of Met XL R 25/2.5 Tablet 15's with ketoconazole may increase the blood level of Met XL R 25/2.5 Tablet 15's.

How to manage the interaction:
Although taking Met XL R 25/2.5 Tablet 15's with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
RamiprilTizanidine
Severe
How does the drug interact with Met XL R 25/2.5 Tablet 15's:
Taking Met XL R 25/2.5 Tablet 15's with Tizanidine may have additive effects in lowering your blood pressure

How to manage the interaction:
Although taking Met XL R 25/2.5 Tablet 15's together with Tizanidine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate. If you have the above symptoms, avoid tasks requiring attentiveness, such as driving or using dangerous machinery. Be careful when you stand up from a sitting or lying position. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eating a healthy and balanced diet can help if you have high blood pressure or a heart problem.

  • Do regular physical activity or exercise.

  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet.

  • Quitting smoking is the best strategy to lower the risk of heart disease. 

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega 3 fatty acid containing food/drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Met XL R 25/2.5 Tablet Substitute

Substitutes safety advice
  • Prolomet R 25 Tablet 10's

    18.36per tablet
  • Cardace Meto 2.5 Tablet 10's

    22.01per tablet
  • Starpress R XL 25 Tablet 10's

    22.10per tablet
  • Ace Revelol 25/2.5 Tablet 10's

    18.41per tablet
  • Ramistar-M XL 25 Tablet 10's

    20.07per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Met XL R 25/2.5 Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Met XL R 25/2.5 Tablet is not recommended during pregnancy.

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Breast Feeding

Unsafe

Met XL R 25/2.5 Tablet is not recommended while breastfeeding.

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Driving

Caution

Met XL R 25/2.5 Tablet may cause dizziness or tiredness. If you feel dizzy or tired, do not drive or use any tools or machines.

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Liver

Caution

Met XL R 25/2.5 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Met XL R 25/2.5 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Met XL R 25/2.5 Tablet is not recommended in children. The safety and efficacy of Met XL R 25/2.5 Tablet in children have not been established.

FAQs

Met XL R 25/2.5 Tablet is indicated in the treatment of hypertension (high blood pressure).
Met XL R 25/2.5 Tablet contains metoprolol and ramipril. Metoprolol is a beta-blocker that slows the heart rate and increases the heart's efficiency in pumping blood throughout the body. Ramipril is an ACE inhibitor that relaxes blood vessels and reduces stress on the heart, allowing blood to flow more freely. Thus, Met XL R 25/2.5 Tablet effectively treats or manages hypertension.
Met XL R 25/2.5 Tablet may cause dizziness or light-headedness. It does not require medical attention and will resolve gradually over time in most cases. Talk to your doctor if you experience this condition persistently. If you experience dizziness, do not drive until you are alert.
If you forget to take Met XL R 25/2.5 Tablet , take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and revert to the original dosing schedule. Do not take a double dose to make up for a forgotten dose.
Inform your doctor that you are taking Met XL R 25/2.5 Tablet if you are due to undergo any surgery. Metoprolol in Met XL R 25/2.5 Tablet can lower your blood pressure too much when it is combined with some anaesthetics.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.
It is recommended that serum potassium and sodium levels be checked regularly. In patients with impaired renal function, serum potassium levels must be checked more frequently.
Met XL R 25/2.5 Tablet is not recommended in children. The safety and efficacy of Met XL R 25/2.5 Tablet in children have not been established.
Met XL R 25/2.5 Tablet is composed of Metoprolol (a beta-blocker) and Ramipril (angiotensin-converting enzyme inhibitor).
To effectively control your high blood pressure while on metoprolol and ramipril, adhere to your doctor's guidance, adopt a healthy lifestyle, regularly check your blood pressure, and be mindful of potential side effects.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MET1774

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