Met XL AM 25/5 Tablet belongs to the class of drugs known as antihypertensive, used to treat hypertension (increased blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of stroke and heart attacks.

Met XL AM 25/5 Tablet contains Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker, while Metoprolol belongs to a group of medicines called beta-blockers. Metoprolol relaxes blood vessels by blocking the action of certain natural substances in your body. On the other hand, Amlodipine widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Together, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Met XL AM 25/5 Tablet is prescribed to adults and children more than six years of age.

Met XL AM 25/5 Tablet can be taken with or without food as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it. Met XL AM 25/5 Tablet is preferable to take at the same time every day for better results. Met XL AM 25/5 Tablet is generally safe to consume. Some people may experience nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Most of the side effects of Met XL AM 25/5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Don't stop taking $ name without talking to your doctor first. Stopping Met XL AM 25/5 Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over some time to help prevent these symptoms. It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Met XL AM 25/5 Tablet as it can increase the concentration of Met XL AM 25/5 Tablet and worsen its side effects.

Met XL AM 25/5 Tablet is used to treat heart-related conditions like angina (chest pain) and high blood pressure. Amlodipine is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart that relaxes and widens the heart smooth muscles for better blood flow. Metoprolol plays a vital role in relaxing our blood vessels and lowering blood pressure by blocking the action of certain natural substances in your body.  Besides this, Met XL AM 25/5 Tablet help prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements. It improves an individual’s tolerance to physical activity and exercise to keep their blood pressure normal during exercise. As a result, heart rate is at maximum, and exercise does not affect the blood pressure in anyways.

• Oedema (swelling)
• Dizziness
• Flushing
• Palpitation
• Vertigo
• Bradycardia (slow heart rate)
• Headache
• Feeling exhausted
• Swollen ankles
• Flushing
• Stomach upset
• Increased levels of potassium in the blood
• Dry mouth
• Change in taste
• Blurred vision
• Difficulty in breathing
• Cold fingers or toes

Don't stop taking the medication without talking to your doctor first. Stopping Met XL AM 25/5 Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Met XL AM 25/5 Tablet can cause low blood sugar (hypoglycaemia). This medication should be used with caution if you have diabetes, particularly if you are taking insulin or other diabetes drugs that may cause low blood sugar. This medication can also induce low blood sugar in babies, children and adults who do not have diabetes. Do not take Met XL AM 25/5 Tablet if you have asthma or similar breathing difficulties. It could make your asthma severe.

Drug-Drug Interaction: Met XL AM 25/5 Tablet is known to interact with blood pressure-lowering drugs (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, nebivolol, sotalol, lisinopril, enalapril, diltiazem, prazosin, terazosin, doxazosin), asthma medications (theophylline), diuretics (fluoxetine), an antidepressant (paroxetine), heart rhythm related medicines (propafenone, digoxin), antifungal (ketoconazole, itraconazole), and antiviral (ritonavir).

Drug-Food Interaction: Met XL AM 25/5 Tablet severely interact with grapefruit and rich protein foods. Hence it should not be taken with Met XL AM 25/5 Tablet . Using Met XL AM 25/5 Tablet together with multivitamins/minerals may decrease the effects of Met XL AM 25/5 Tablet . If it necessary to take you should maintain at least 2 hours of a gap in between the administration of Met XL AM 25/5 Tablet and multivitamins/minerals.

Drug-Disease Interaction: Met XL AM 25/5 Tablet should not be given to the people with diabetes, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.

• ATENOLOL
• BISOPROLOL
• METOPROLOL
• NEBIVOLOL
• SOTALOL
• LISINOPRIL
• ENALAPRIL
• DILTIAZEM
• PRAZOSIN
• THEOPHYLLINE
• FLUOXETINE
• PAROXETINE
• DIGOXIN
• KETOCONAZOLE
• ITRACONAZOLE
• RITONAVIR

• Keep your weight under control with BMI 19.5-24.9.

• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

• If you are taking alcohol then only one serving for women and two servings for men is advisable.

• Quitting smoking is the best strategy to lower the risk of heart disease. 

• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

• Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.

• Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.