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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 4, 2024 | 9:21 AM IST

Mesalo OD Tablet is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Mesalo OD Tablet

Mesalo OD Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Mesalo OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Mesalo OD Tablet as prescribed. You are advised to use Mesalo OD Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Mesalo OD Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Mesalo OD Tablet if you are allergic to Mesalazine or any other medicines. Mesalo OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesalo OD Tablet . Avoid taking Mesalo OD Tablet if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Mesalo OD Tablet immediately and consult a doctor.

Uses of Mesalo OD Tablet

Mesalo OD Tablet is used in the treatment of Ulcerative colitis and Crohn's disease

Medicinal Benefits

Mesalo OD Tablet contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesalo OD Tablet may prevent further episodes of ulcerative colitis.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mesalo OD Tablet

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Flatulence (gas)

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Mesalo OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesalo OD Tablet . Avoid taking Mesalo OD Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Mesalo OD Tablet . Therefore, if you notice any skin reactions while taking Mesalo OD Tablet , please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Mesalo OD Tablet immediately and consult a doctor. Avoid taking Mesalo OD Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking laxatives (lactulose), painkillers (aspirin, ibuprofen), immunosuppressants (azathioprine), or chemotherapy drugs (thioguanine, mercaptopurine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: If you have a stomach ulcer, asthma or other lung problems, or any medical condition that can cause bleeding, liver, kidney or blood problems, inform your doctor before taking Mesalo OD Tablet .

Drug-Drug Interactions Checker List

  • LACTULOSE
  • ASPIRIN
  • IBUPROFEN
  • AZATHIOPRINE
  • THIOGUANINE
  • MERCAPTOPURINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids. Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Special Advise

  • Blood and urine tests are recommended before and during the treatment with Mesalo OD Tablet to monitor the functioning of kidney, liver and blood.

Disease/Condition Glossary

Ulcerative colitis: It is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite or nausea. The factors involved in causing ulcerative colitis include immune disorders and environmental factors like viruses, bacteria or antigens, which may trigger the immune system and genes inherited from the parent.

Crohn’s disease: It is a type of chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract, from mouth to anus. But mostly occurs in the small intestine and large intestine. The symptoms include blood in stools, stomach cramps, tiredness, diarrhoea, fever, weight loss or loss of appetite.

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Alcohol

Consult your doctor

The interaction of alcohol with Mesalo OD Tablet is unknown. If you have concerns, please discuss them with your doctor before taking Mesalo OD Tablet .

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Pregnancy

Consult your doctor

Mesalo OD Tablet is a Category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before taking Mesalo OD Tablet .

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Breast Feeding

Caution

Mesalo OD Tablet should not be taken by breastfeeding mothers unless advised by the doctor. Granules form of Mesalazine may cause allergic reactions such as diarrhoea in newborn babies after breastfeeding. If this happens, discontinue breastfeeding.

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Driving

Safe

Mesalo OD Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor if you have liver problems before using Mesalo OD Tablet .

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Kidney

Caution

Mesalo OD Tablet should be used with extreme caution in patients with mild to moderate kidney impairment. Avoid taking Mesalo OD Tablet if you have severe kidney impairment.

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Children

Caution

Mesalo OD Tablet is not recommended for children below two years. However, Mesalo OD Tablet should be given to children only if recommended by a doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - MES0073

Author Details

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FAQs

Mesalo OD Tablet is used to treat Ulcerative colitis and Crohn's disease.
Mesalo OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
You are not recommended to take Mesalo OD Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesalo OD Tablet with other medicines.
Yes, Mesalo OD Tablet may cause kidney stones in some patients. It is not necessary for everyone taking Mesalo OD Tablet to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Mesalo OD Tablet to prevent kidney stones.
Mesalo OD Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Mesalo OD Tablet .
Yes, Mesalo OD Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Mesalo OD Tablet to prevent dehydration.

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