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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mesalo OD Tablet is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Composition :

MESALAZINE-1200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mesalo OD Tablet

Mesalo OD Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Mesalo OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Mesalo OD Tablet as prescribed. You are advised to use Mesalo OD Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Mesalo OD Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Mesalo OD Tablet if you are allergic to Mesalazine or any other medicines. Mesalo OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesalo OD Tablet . Avoid taking Mesalo OD Tablet if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Mesalo OD Tablet immediately and consult a doctor.

Uses of Mesalo OD Tablet

Mesalo OD Tablet is used in the treatment of Ulcerative colitis and Crohn's disease

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Mesalo OD Tablet contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesalo OD Tablet may prevent further episodes of ulcerative colitis.

How Mesalo OD Tablet Works

Mesalo OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mesalo OD Tablet

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Flatulence (gas)

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Mesalo OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesalo OD Tablet . Avoid taking Mesalo OD Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Mesalo OD Tablet . Therefore, if you notice any skin reactions while taking Mesalo OD Tablet , please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Mesalo OD Tablet immediately and consult a doctor. Avoid taking Mesalo OD Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

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MesalazineCidofovir
Critical
MesalazineOmeprazole
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Mesalo OD Tablet:
Co-administration of Mesalo OD Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesalo OD Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of omeprazole with Mesalo OD Tablet can decrease the effects of Mesalo OD Tablet.

How to manage the interaction:
There could be a possible interaction between Mesalo OD Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Deferasirox with Mesalo OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Mesalo OD Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Iomeprol with Mesalo OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalo OD Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Tenofovir alafenamide with Mesalo OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Mesalo OD Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Metrizamide with Mesalo OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalo OD Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Ranitidine with Mesalo OD Tablet can decrease the levels of Mesalo OD Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalo OD Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Nizatidine with Mesalo OD Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Mesalo OD Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Mesalo OD Tablet:
Co-administration of Iodamide with Mesalo OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids. Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Mesalo OD Tablet Substitute

Substitutes safety advice
  • Vegaz OD 1.2 gm Tablet 15's

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  • Versames 1200 Tablet 10's

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    34.65per tablet
  • Rowasa OD 1200 Tablet 10's

    by Others

    27.00per tablet
  • Vegaz OD Tablet 10's

    by Others

    67.37per tablet
  • Mesarem 1200 Tablet 15's

    by Others

    28.62per tablet
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Alcohol

Consult your doctor

The interaction of alcohol with Mesalo OD Tablet is unknown. If you have concerns, please discuss them with your doctor before taking Mesalo OD Tablet .

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Pregnancy

Consult your doctor

Mesalo OD Tablet is a Category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before taking Mesalo OD Tablet .

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Breast Feeding

Caution

Mesalo OD Tablet should not be taken by breastfeeding mothers unless advised by the doctor. Granules form of Mesalazine may cause allergic reactions such as diarrhoea in newborn babies after breastfeeding. If this happens, discontinue breastfeeding.

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Driving

Safe

Mesalo OD Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor if you have liver problems before using Mesalo OD Tablet .

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Kidney

Caution

Mesalo OD Tablet should be used with extreme caution in patients with mild to moderate kidney impairment. Avoid taking Mesalo OD Tablet if you have severe kidney impairment.

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Children

Caution

Mesalo OD Tablet is not recommended for children below two years. However, Mesalo OD Tablet should be given to children only if recommended by a doctor.

FAQs

Mesalo OD Tablet is used to treat Ulcerative colitis and Crohn's disease.

Mesalo OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

You are not recommended to take Mesalo OD Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesalo OD Tablet with other medicines.

Yes, Mesalo OD Tablet may cause kidney stones in some patients. It is not necessary for everyone taking Mesalo OD Tablet to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Mesalo OD Tablet to prevent kidney stones.

Mesalo OD Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Mesalo OD Tablet .

Yes, Mesalo OD Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Mesalo OD Tablet to prevent dehydration.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - MES0073

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