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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:07 PM IST
Meroprl 1 gm Injection is an antibiotic used to treat severe bacterial infections. It treats bacterial infections of various body parts like skin, soft tissues, blood, brain (meningitis), lungs (pneumonia), urinary tract. It contains Meropenem, which prevents the formation of the bacterial protective cell wall required for bacteria to survive. Thus, it kills the bacteria.
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Prescription drug

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Composition

MEROPENEM-1000MG

Manufacturer/Marketer

Pristine Pearl Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Meroprl 1 gm Injection

Meroprl 1 gm Injection is used to treat severe bacterial infections. It treats bacterial infections of various body parts like skin, soft tissues, blood, brain (meningitis), lungs (pneumonia), and urinary tract. A bacterial infection is a condition in which bacteria grows in the body and causes infection. It can target any body part and multiple very quickly.

Meroprl 1 gm Injection contains Meropenem, which helps to treat bacterial infections by killing the bacteria (bactericidal). It prevents the formation of the bacterial protective cell wall, which is required for bacteria to survive. And it helps treat bacterial infections effectively.

You are advised to take Meroprl 1 gm Injection for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience nausea, vomiting, diarrhoea, constipation, headache, pain, redness, pain, or swelling at the injection site, insomnia (difficulty falling asleep or staying asleep), and sores in the mouth or throat. Most of these side effects of Meroprl 1 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known allergic to Meroprl 1 gm Injection or any other medicines, let your doctor know. Inform your doctor if you have ever had a kidney or liver disease, seizures (fits), or epilepsy. If you have watery and bloody stools, please visit your doctor immediately, as this could be a sign of a new infection. Regular monitoring of kidney function and the blood cell count is required while taking Meroprl 1 gm Injection.

Uses of Meroprl 1 gm Injection

Treatment of Severe Bacterial Infections.

Medicinal Benefits

Meroprl 1 gm Injection is a broad-spectrum antibiotic containing Meropene known to fight against a wide variety of bacterial infections. It is used to treat infections of various body parts like complicated skin and soft tissue infections, blood, lungs (pneumonia including ventilator-associated pneumonia), and severe urinary tract infections. It also effectively treats infection in the brain, known as meningitis (infection of the membranes surrounding the brain and spinal cord). It works by killing the bacteria (bactericidal). It prevents the formation of a bacterial protective cell wall, which is required for bacteria to survive. And effectively treat bacterial infection.

Directions for Use

Meroprl 1 gm Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Meroprl 1 gm Injection

  • Pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Constipation
  • Abdominal (stomach) pain.
  • Insomnia (difficulty falling asleep or staying asleep)
  • Redness, pain, or swelling at the injection site
  • Sores in the mouth or throat

Drug Warnings

Do not take Meroprl 1 gm Injection if you are allergic or have had a severe reaction to meropenem or any other ingredients of Meroprl 1 gm Injection. Inform your doctor if you have or have ever had kidney disease, seizures (fits), epilepsy or if you participate in regular physical activity. Patients with epilepsy should tell their doctor before taking Meroprl 1 gm Injection. If you have watery and bloody stools, please visit your doctor immediately, as this could be a sign of a new infection.

Drug Interactions

Drug-Drug Interaction: Meroprl 1 gm Injection is known to interact with anti-epilepsy medicines (valproic acid, divalproex sodium), and anti-gout medicine (probenecid). 

Drug-Food Interaction: Meroprl 1 gm Injection should not be taken along with alcohol as it might further affect mental alertness and cause excessive drowsiness.

Drug-Disease Interaction: Meroprl 1 gm Injection is known to interact in people having a brain or brain tumour, epilepsy, kidney disease or if you are on dialysis.

Drug-Drug Interactions Checker List

  • VALPROIC ACID
  • DIVALPROEX SODIUM
  • PROBENECID

Habit Forming

No

Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Meroprl 1 gm Injection may increase nervousness, sleeplessness, and anxiety caused by caffeine.

  • Probiotics should be taken after taking the full course of Meroprl 1 gm Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 

  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Meroprl 1 gm Injection.

  • Avoid alcoholic beverages with Meroprl 1 gm Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Meroprl 1 gm Injection in fighting off infections.

Special Advise

  • Do not take valproic acid with Meroprl 1 gm Injection as it is contra-indicate.

  • Regularly monitor your kidney function and blood count while taking Meroprl 1 gm Injection.

Disease/Condition Glossary

Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine can be more prone to bacterial infection.

Meningitis: It is a bacterial infection of the membranes that surround the brain and spinal cord.

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Alcohol

Caution

Meroprl 1 gm Injection can affect alertness and coordination. So, alcohol consumption should be avoided as it might further reduce alertness and cause excessive drowsiness.

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Pregnancy

Caution

Meroprl 1 gm Injection is a category B pregnancy drug. It is not known to harm the baby. But it should only be taken if prescribed by a doctor.

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Breast Feeding

Caution

Meroprl 1 gm Injection should only be taken in breastfeeding women if prescribed by a doctor.

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Driving

Caution

Meroprl 1 gm Injection can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Meroprl 1 gm Injection to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Meroprl 1 gm Injection to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Meroprl 1 gm Injection is generally safe for children aged above 3 months. A doctor should only give it at a hospital.

Country of origin

India

Manufacturer/Marketer address

81, 134, 4Th Main Rd, Keb Colony, New Gurappana Palya, Jayanagara 9Th Block, Btm Layout, Bengaluru, Karnataka 560029
Other Info - MER0524

Author Details

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FAQs

Meroprl 1 gm Injection belongs to a class of drugs known as 'antibiotics', primarily used to treat severe bacterial infections.
Meroprl 1 gm Injection is a broad-spectrum antibiotic containing Meropene that works by killing the bacteria (bactericidal in nature). It prevents the formation of a bacterial protective cell wall, which is required for bacteria to survive. And effectively treat bacterial infection.
Antibiotic medicines like Meroprl 1 gm Injection can cause diarrhea, which may be a sign of a new infection. If you have watery or bloody stool, visit your doctor immediately. Also, do not use any anti-diarrheal medicines on your own unless suggested by your doctor.
No, Meroprl 1 gm Injection is known to contra-indicate with valproic acid and increase the episodes of seizures. So, both medicines should not be taken together to avoid any unpleasant side effects.
Yes, Meroprl 1 gm Injection can cause a serious allergic reaction, including anaphylaxis (serious allergic reaction to a medication), which can be life-threatening. If you have itching, trouble breathing or swallowing, and have swelling in your hands or face, please visit your doctor.
The most common side effects are nausea, vomiting, diarrhea, constipation, headache, pain, redness, pain, or swelling at the injection site. Most of these side effects of Meroprl 1 gm Injection do not require medical attention and gradually resolve over time.
Drug resistance is a condition which occurs when the bacteria gets modified in the body and stops reacting to the medicine. As a result, the medicine no longer works. Resistance to Meroprl 1 gm Injection is not very common at least for the bacteria against which it works.
Although rare reports indicate that Meroprl 1 gm Injection may decrease the blood sugar levels, it does not affect everyone. However, it is important to regularly monitor your blood sugar levels. If you experience any sudden drop in blood sugar levels, consult your doctor.
Meroprl 1 gm Injection is generally safe for children above 3 months of age. It is only administered by a doctor at a hospital.
No, do not stop taking Meroprl 1 gm Injection without consulting your doctor even if you feel better as it may increase the risk of developing an infection that is resistant to medication. Therefore, complete full course of treatment.

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