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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:50 PM IST
Meprate Tablet is used to treat the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. It contains Medroxyprogesterone, which works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms. It may sometimes cause side effects such as breast tenderness, swelling in other body parts, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding.
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Prescription drug

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Manufacturer/Marketer :

Serum Institute Of India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Meprate Tablet

Meprate Tablet is a female hormone known as progestin (a form of progesterone) that regulates ovulation (the release of an egg from an ovary). It treats the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Meprate Tablet contains medroxyprogesterone. Meprate Tablet works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms.

Your doctor will advise your dose and how often you need to take this medication based on your medical condition. You may sometimes have breast tenderness, swelling in other body parts, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Meprate Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Using Meprate Tablet may increase the risk of blood clots. Make sure that before taking this medicine, you inform your doctor if you have or have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any kind of unpleasant side-effect. Meprate Tablet should not be used in heart disease or dementia patients because this medicine may increase your risk of developing these conditions.

Uses of Meprate Tablet

Treatment of Amenorrhea (absence of menstruation), Uterine bleeding, Endometrial hyperplasia (thickening of uterus).

Medicinal Benefits

Meprate Tablet is a female hormone that regulates ovulation and menstruation in women. Meprate Tablet helps in initiating the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT). Meprate Tablet is used to prevent thickening of the uterine lining in postmenopausal women receiving estrogens who have not removed their uterus through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months). It is also given in combination with estrogens as part of menopausal replacement therapy. The injection form of Meprate Tablet is prescribed for treating abnormal uterine bleeding along with irregular or ceased menstrual cycles. The intravaginal gel form of Meprate Tablet assists in reproductive technology for infertile women with progesterone deficiency or irregular or ceased menstrual cycle. The vaginal insert form of Meprate Tablet supports early pregnancy and implantation of an embryo in the uterus. Off-label use of Meprate Tablet helps in reducing the risk of preterm birth.

Side Effects of Meprate Tablet

  • Headache

  • Breast pain

  • Irregular vaginal bleeding or spotting

  • Stomach/abdominal cramps

  • Bloating

  • Nausea

  • Vomiting

  • Hair loss

  • Fluid retention

  • Vaginal yeast infection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Meprate Tablet with estrogen should not be used to prevent heart disease, heart attacks, strokes, or dementia. Using Meprate Tablet with estrogen may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. In some cases, using Meprate Tablet with estrogen may produce dementia among women aged 65 and older. Do not use Meprate Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Meprate Tablet if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, are pregnant, breastfeeding or planning to get pregnant, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. Tell your doctor about this if you use Meprate Tablet before lab tests or biopsies, as it can affect the report values. Diagnostic tests of blood coagulation, thyroid, cholesterol, and glucose metabolism results might affect people using Meprate Tablet .

Therapeutic Class

HORMONES

Drug-Drug Interactions

verifiedApollotooltip
MedroxyprogesteroneAcitretin
Critical
MedroxyprogesteroneEtretinate
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Besides this, weight-bearing exercises can help in making your bones strong. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.
  • Try to apply vaginal lubricant or moisturizer if you have vaginal dryness.

Habit Forming

No

How Meprate Tablet Works

Meprate Tablet contains medroxyprogesterone. Meprate Tablet works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms.

What if I have taken an overdose of Meprate Tablet

Do not take more than the prescribed dose of Meprate Tablet as it may cause overdose. The symptoms of overdose include seizures (fits), vomiting, nausea, trouble breathing and altered mental status. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Caution

There is not enough scientific data available for Meprate Tablet interaction with alcohol; hence, it is best to consult a doctor.

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Pregnancy

Caution

Contact the doctor before using Meprate Tablet . Your doctor will decide whether Meprate Tablet should be given to the pregnant woman or not, depending on her condition.

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Breast Feeding

Safe if prescribed

Clinical evidence suggests that Meprate Tablet may pass into breast milk, but its risk is not established. So it is better to contact the doctor before using Meprate Tablet .

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Driving

Unsafe

It is advised to drive with caution after taking Meprate Tablet as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

Meprate Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

There is not enough scientific data available for Meprate Tablet interaction with the kidney; hence it is best to consult a doctor.

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Children

Unsafe

Meprate Tablet is not recommended for children below 12 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India.
Other Info - MEP0007

Author Details

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FAQs

Meprate Tablet is used to regulate ovulation (the release of an egg from an ovary). It treats the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Meprate Tablet helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.
Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive, weight gain, or gallbladder problems.
Yes, Meprate Tablet may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Meprate Tablet , please consult your doctor.
Do not use Meprate Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancers (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Meprate Tablet if you had a heart attack, stroke, blood clot, liver problems, pregnant, breastfeeding, or planning to get pregnant or allergic to Meprate Tablet .
No, Meprate Tablet is not a contraceptive. It should not be used as an effective form of birth control to prevent pregnancy.
Meprate Tablet should be taken in the dose and duration as prescribed by the doctor.
Yes, Meprate Tablet is a synthetic pregnant steroid and a derivative of progesterone.
Less serious but common side effects of Meprate Tablet include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.
Meprate Tablet is safe and effective if used as per prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.
No, Meprate Tablet does not cause withdrawal bleeding. However, if you notice symptoms such as bleeding or spotting even after completing the treatment, inform your doctor.
Take Meprate Tablet as advised by your doctor. The dose and duration depends on your medical condition. It can be taken with or without food, but try to take it at the same time every day to maintain consistent levels of Meprate Tablet in your body. Swallow it as whole with a glass of water. Do not break, crush or chew it.
Ideally, you should try not to miss a dose of Meprate Tablet as missing a dose increases the chance of breakthrough vaginal bleeding or spotting (blood stain). However, if you miss a dose of Meprate Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

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