apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Mephentermine Injection 1ml is used to treat hypotension (low blood pressure). Besides this, it is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension. It contains Mephentermine, which helps to release a chemical messenger (adrenaline), that compresses the blood vessels. It increases blood pressure rapidly by increasing the pumping capacity of the heart and narrowing the blood vessels of the heart. Some people may experience side effects such as systemic hypertension (high blood pressure), anxiety, insomnia (difficulty in sleeping), and CNS stimulation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Not for online sale
Prescription drug
 Trailing icon
Consult Doctor

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Mephentermine Injection 1ml

Mephentermine Injection 1ml belongs to a category of medications called ‘Antihypotensives’ primarily used to treat hypotension (low blood pressure). Besides this, Mephentermine Injection 1ml is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension. Hypotension is a condition when blood pressure drops below the normal range, which may reduce cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and a risk of injury from falls.

Mephentermine Injection 1ml contains ‘Mephentermine’ is a class of medicines called sympathomimetic. It helps to release a chemical messenger (adrenaline), which compresses the blood vessels. It increases blood pressure rapidly by increasing the pumping capacity of the heart and narrowing the blood vessels of the heart.  Hence, it works to increase your blood pressure.

Mephentermine Injection 1ml will be administered by a healthcare professional. Do not self-administer Mephentermine Injection 1ml. Some people may experience systemic hypertension (high blood pressure), anxiety, insomnia (difficulty in sleeping), and CNS stimulation. Most of these side effects of Mephentermine Injection 1ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Mephentermine Injection 1ml. It should not be used in children below 18 years. Mephentermine Injection 1ml should be used with caution in patients with having heart disease, overactive thyroid, shock, dehydration, or acidosis (increased acid level in blood). Do not take Mephentermine Injection 1ml if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. If you have high blood pressure, kidney or liver problems, or coronary artery disease, inform your doctor before taking Mephentermine Injection 1ml.

Uses of Mephentermine Injection 1ml

Treatment of Hypotension (low blood pressure)

Medicinal Benefits

Mephentermine Injection 1ml consists of Mephentermine is a sympathomimetic medicine. It helps to release a chemical messenger (adrenaline), which compresses the blood vessels. It increases the blood pressure rapidly by increasing the pumping capacity of the heart and narrowing the blood vessels of the heart.  Hence, it works to increase your blood pressure. Mephentermine Injection 1ml also used by anesthesiologist and intensive care specialist to treat hypotension (decreased blood pressure) due to vasodilation caused by general, epidural, and spinal anesthesia (caesarian section).

Directions for Use

Mephentermine Injection 1ml will be administered by a healthcare professional. Do not self-administer Mephentermine Injection 1ml.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mephentermine Injection 1ml

  • Systemic hypertension (high blood pressure)
  • Anxiety
  • Insomnia (difficulty in sleeping)
  • CNS stimulation

Drug Warnings

Tell your doctor if you are allergic to Mephentermine Injection 1ml, or any of its ingredients. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines, and herbal supplements. Mephentermine Injection 1ml is not recommended during pregnancy or breastfeeding unless prescribed by a doctor. Mephentermine Injection 1ml should not be given to children as safety and effectiveness have not been established. Before using Mephentermine Injection 1ml, tell your doctor if you have liver/kidney problems, hypertension, overactive thyroid, shock, dehydration, acidosis. Do not drive or handle machinery unless you are alert. Mephentermine Injection 1ml is not recommended in the treatment of hypotension (low blood pressure) induced by chlorpromazine because it may potentiate, rather than correct. Inform your doctor if you are taking or have recently taken medication to treat severe depression.  

Drug Interactions

Drug-drug interactions: Mephentermine Injection 1ml may interact with central nervous system stimulants (amphetamine, dextroamphetamine, lisdexamfetamine), respiratory stimulants (guaifenesin, phenylpropanolamine, phenylephrine), a drug used for thyroid disorder (levothyroxine), medicines used for weight loss (phentermine), anti-depressant (isocarboxazid, phenelzine, selegiline, and tranylcypromine).

 

Drug-food interactions: No interaction found.

 

Drug-disease interactions: Mephentermine Injection 1ml should be used with caution in patients with hypertension, heart disease, dehydration and acidosis (buildup acid in the blood).

Drug-Drug Interactions Checker List

  • AMPHETAMINE
  • DEXTROAMPHETAMINE
  • GUAIFENESIN+BROMHEXINE
  • PHENYLEPHRINE
  • LEVOTHYROXINE SODIUM
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Add foods with high vitamin B12, including eggs, fortified cereals, and nutritional yeast to your daily diet.
  • Salty foods can increase blood pressure. Try eating canned soup, cottage cheese, olives, and pickled items.
  • Drink coffee and caffeinated tea; it may spike blood pressure by stimulating the cardiovascular system.
  • Eat small meals more frequently; large meals may drop in blood pressure as your body works harder to digest larger meals.
  • Drink more water and limit alcohol; dehydration lowers blood pressure.
  • Change body position standing up slowly.
  • Avoid prolonged bed rest.
  • If you exercise outdoors in extreme heat, take frequent breaks.
  • Avoid spending a long time in saunas, hot tubs, and steam rooms which cause dehydration.

Special Advise

Do not take Mephentermine Injection 1ml if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days; it may cause serious drug interaction.

Disease/Condition Glossary

Hypotension: Low blood pressure is a condition when blood pressure drops below the normal range, which may reduce cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and a risk of injury from falls. Also, severely low blood pressure can deprive your body of enough oxygen to carry out its functions, leading to damage to your heart and brain. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. Ideal blood pressure should be 120/80 mmHg. Hypotension exists when the systolic pressure is less than 90 mmHg, and the diastolic pressure is less than 60 mmHg. 

bannner image

Alcohol

Caution

It is not known if alcohol interacts with Mephentermine Injection 1ml. Please consult your doctor if you have any concerns regarding this.

bannner image

Pregnancy

Unsafe

Mephentermine Injection 1ml may increase uterine contractions in pregnant women, especially during the third trimester Please consult your doctor before taking Mephentermine Injection 1ml if you are pregnant or planning for pregnancy.

bannner image

Breast Feeding

Unsafe

It is unknown whether Mephentermine Injection 1ml is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

bannner image

Driving

Caution

It is not known whether Mephentermine Injection 1ml alerts the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

bannner image

Liver

Caution

Mephentermine Injection 1ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Mephentermine Injection 1ml to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Mephentermine Injection 1ml is not recommended for children below 18 years of age. However, please consult a doctor before giving Mephentermine Injection 1ml to children.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802 / 1901, Plot No. C-70, G-Block,Bandra Kurla Complex, Bandra (East),Mumbai,Maharashtra,INDIA,400051.
Other Info - MEP0033

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Mephentermine Injection 1ml is used to treat hypotension (low blood pressure). Besides this, Mephentermine Injection 1ml is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension.
Do not stop taking Mephentermine Injection 1ml on your own. You are advised to take Mephentermine Injection 1ml for as long as your doctor has prescribed it for you depending on your medical condition. Do not be hesitant to speak with your doctor if you experience any difficulty while taking Mephentermine Injection 1ml.
Do not take Mephentermine Injection 1ml if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Mephentermine Injection 1ml only if the benefits outweigh the risks.
Antidepressants, along with Mephentermine Injection 1ml, especially monoamine oxidase inhibitors (MAOI’s) may prolong and increase the effects of Mephentermine Injection 1ml. Consult your doctor before taking Mephentermine Injection 1ml with other medicines to avoid unpleasant side-effects.
Systemic hypertension (high blood pressure), Anxiety, Insomnia (difficulty in sleeping), CNS stimulation are the common side-effects of Mephentermine Injection 1ml.Â
A person should tell their doctor if they have a history of heart disease, overactive thyroid, shock, high blood pressure, persistent and lasting illness, during pregnancy, and breastfeeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.