Megamentin 375 mg Tablet is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

Megamentin 375 mg Tablet consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. Megamentin 375 mg Tablet does not work against infections caused by viruses, including colds and flu.

The dose of Megamentin 375 mg Tablet can vary depending on your condition and the severity of the infection. Also, it is recommended to complete the course of medicine even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance). The common side effects of Megamentin 375 mg Tablet include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Megamentin 375 mg Tablet, please inform your doctor if you have any allergy (against any antibiotic) or kidney or liver problems. Do not take Megamentin 375 mg Tablet on your own as self-medication since it may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Megamentin 375 mg Tablet is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Megamentin 375 mg Tablet is a broad-spectrum antibiotic that covers a very wide range of bacterial infections. Megamentin 375 mg Tablet has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy. Besides this, it helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase. This makes the drug effective in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.

• Vomiting
• Diarrhea
• Indigestion

After taking Megamentin 375 mg Tablet, if you have an allergy-like symptom, including rash, swelling of the face/lips/throat, difficulty breathing, or tight chest tightness, immediately contact your doctor. Do not take Megamentin 375 mg Tablet if you have an allergy to Megamentin 375 mg Tablet, penicillin or cephalosporin class of antibiotics. People with liver diseases or jaundice (yellowing of skin/eye) should not take Megamentin 375 mg Tablet, as it can severely affect the liver. Consult your doctor before taking Megamentin 375 mg Tablet if you are pregnant or breastfeeding. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Drug-Drug Interaction: Caution should be exercised when Megamentin 375 mg Tablet is administered in combination with gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drug (methotrexate), and drug to prevent organ transplant (mycophenolate mofetil).

Drug-Food Interaction: Avoid taking eating high-fat meals as this may make it harder for your body to absorb Megamentin 375 mg Tablet.

Drug-Disease Interaction: People affected with liver disease (like jaundice), glandular fever (viral infection with fever and sore throat), or colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take Megamentin 375 mg Tablet.

• ALLOPURINOL
• PROBENECID
• WARFARIN
• METHOTREXATE
• MYCOPHENOLATE MOFETIL

• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.

• Whole grains like whole-grain bread and brown rice should be included in your diet.

• Probiotics should be taken after taking a full course of Megamentin 375 mg Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.

• Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.

• Avoid alcoholic beverages with Megamentin 375 mg Tablet as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Megamentin 375 mg Tablet in fighting off infections.

• Even if you feel better after taking Megamentin 375 mg Tablet, do not stop taking it until your doctor says so. This might cause the symptoms to reappear and make the infection difficult to treat due to antibiotic resistance.

• Make sure you drink plenty of fluids when you are sick. This will, in general, help you clear out the infection faster, protect you from dehydration, and help you overcome some unpleasant side effects of taking Megamentin 375 mg Tablet.

• Some people may be allergic to Megamentin 375 mg Tablet or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine, particularly antibiotics belonging to these groups.

Bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any part of the body and multiply very quickly. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. You can experience generalised symptoms like fevers, chills, and fatigue when you get infected with bacteria. A few harmful bacteria commonly cause infections are Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.