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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Megacet DS Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also shrinks the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Systemic Healthcare

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Megacet DS Syrup

Megacet DS Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs or talks.

Megacet DS Syrup is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that works by shrinking the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and nasal congestion.

Take Megacet DS Syrup as prescribed. Your doctor will recommend you how often you take Megacet DS Syrup based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Most of these side effects of Megacet DS Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Megacet DS Syrup or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Megacet DS Syrup. Do not use Megacet DS Syrup in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Megacet DS Syrup is not recommended for children below 4 years. Please do not take more than the prescribed dose of Megacet DS Syrup as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Megacet DS Syrup.

Uses of Megacet DS Syrup

Treatment of Common cold and allergies.

Directions for Use

Take the medicine with or without food as advised by a doctor. Swallow it whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Megacet DS Syrup is a combination of three drugs: Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that work by contracting and narrowing the blood vessels. Thus, it provides relief from congestion and decreases mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

How Megacet DS Syrup Works

Megacet DS Syrup is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that works by shrinking the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and nasal congestion.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Megacet DS Syrup

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Constipation
  • Dry mouth

What if I have taken an overdose of Megacet DS Syrup

Do not take more than the prescribed dose of Megacet DS Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Megacet DS Syrup or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Megacet DS Syrup. Do not use Megacet DS Syrup in breastfeeding mothers without doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Megacet DS Syrup is not recommended for children below 4 years. Please do not take more than the prescribed dose of Megacet DS Syrup as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Megacet DS Syrup.

Drug-Drug Interactions

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PhenylephrineTranylcypromine
Critical
PhenylephrineFurazolidone
Critical

Drug-Drug Interactions

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PhenylephrineTranylcypromine
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Taking Tranylcypromine with Megacet DS Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Megacet DS Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Taking Furazolidone with Megacet DS Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Megacet DS Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Megacet DS Syrup 60 ml only after 14 days of stopping Furazolidone.
PhenylephrinePropofol
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Taking Megacet DS Syrup 60 ml with Propofol may lead to increased levels of Megacet DS Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Megacet DS Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Co-administration of Selegiline with Megacet DS Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Megacet DS Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Co-administration of Megacet DS Syrup 60 ml with Sevoflurane can increase the levels of Megacet DS Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Megacet DS Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Taking Megacet DS Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Megacet DS Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Megacet DS Syrup 60 ml:
Taking Megacet DS Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Megacet DS Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrineAmitriptyline
Severe
How does the drug interact with Megacet DS Syrup 60 ml:
Co-administration of Amitriptyline with Megacet DS Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Megacet DS Syrup 60 ml and amitriptyline could interact, but they can still be taken if they are prescribed by a doctor. It is advised to monitor blood pressure regularly. Without consulting a doctor, never stop taking any medications.
PhenylephrineIsocarboxazid
Severe
How does the drug interact with Megacet DS Syrup 60 ml:
Co-administration of Megacet DS Syrup 60 ml with Isocarboxazid can result in extremely high blood pressure which may be serious.

How to manage the interaction:
Although taking Isocarboxazid and Megacet DS Syrup 60 ml together can result in an interaction. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrineClomipramine
Severe
How does the drug interact with Megacet DS Syrup 60 ml:
Co-administration of Clomipramine and Megacet DS Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Clomipramine and Megacet DS Syrup 60 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.

  • Drink plenty of fluids to avoid dehydration.

  • Gargle with salt water for relief from sore throat.

  • Avoid consumption of alcohol with Megacet DS Syrup as it may cause tiredness, drowsiness or lack of concentration.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Megacet DS Syrup Substitute

Substitutes safety advice
  • Maxtra P DS Syrup 60 ml

    1.85per tablet
  • Retherma AC Suspension 60 ml

    1.53per tablet
  • Delcon Plus-DS Suspension 60 ml

    by AYUR

    1.55per tablet
  • Coriminic P DS Orange Flavour Suspension 60 ml

    1.43per tablet
  • Dolocold DS Suspension 60 ml

    1.09per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Megacet DS Syrup as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Megacet DS Syrup.

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Pregnancy

Caution

The safety of Megacet DS Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

Megacet DS Syrup may be excreted in breast milk, and cause harm to the baby. Besides this, Megacet DS Syrup may also slow milk's production, so it is better to contact a doctor before a lactating mother takes it.

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Driving

Caution

Megacet DS Syrup may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Megacet DS Syrup.

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Liver

Caution

Take Megacet DS Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Megacet DS Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Megacet DS Syrup is not recommended for children below 4 years of age. However, please consult a doctor before giving Megacet DS Syrup to children.

FAQs

Megacet DS Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
Megacet DS Syrup contains Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Yes, Megacet DS Syrup contains paracetamol which acts as mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
No, you are not recommended to consume alcohol with Megacet DS Syrup as it may increase the risk of liver damage and cause increased drowsiness, dizziness and lack of concentration.
Megacet DS Syrup is excreted in breast milk and may affect the health of baby. Therefore, if you are breastfeeding, please inform your doctor before taking Megacet DS Syrup so that the doctor may prescribe Megacet DS Syrup if the benefits are greater than risks.
Yes, Megacet DS Syrup may cause drowsiness. It is not necessary for everyone taking Megacet DS Syrup to experience this side effect. Therefore, avoid driving or operate heavy machinery if you feel drowsy after taking Megacet DS Syrup.
No, you are not recommended to take Megacet DS Syrup with Cetirizine as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking Megacet DS Syrup with other medicines.
No, you are not recommended to stop taking Megacet DS Syrup without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Megacet DS Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Megacet DS Syrup, please consult your doctor.
Do not use Megacet DS Syrup if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Megacet DS Syrup if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Megacet DS Syrup may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, immediately contact your doctor and stop taking Megacet DS Syrup.

Country of origin

INDIA

Manufacturer/Marketer address

2nd Floor, Block A, Suryalok Complex, King Koti Rd, Hyderabad, Telangana 500001
Other Info - MEG0249

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