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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
MEFRAN SPAS TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. It contains Dicyclomine and Mefenamic acid which relieve contractions associated with the smooth muscles of the abdomen and reduce mild to moderate pain and inflammation. It may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Synonym :

DICYCLOMINE HYDROCHLORIDE+MEFENAMIC ACID

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

MEFRAN SPAS TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. A colic is a form of pain that starts and stops abruptly.

MEFRAN SPAS TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, MEFRAN SPAS TABLET helps in relieving pain.

You are advised to take MEFRAN SPAS TABLET as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, MEFRAN SPAS TABLET may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. MEFRAN SPAS TABLET may cause dizziness and drowsiness, so drive with caution. MEFRAN SPAS TABLET is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with MEFRAN SPAS TABLET as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Treatment of Abdominal pain, dysmenorrhea (period pain), and colicky pain.
Take MEFRAN SPAS TABLET with food to prevent stomach upset. Swallow MEFRAN SPAS TABLET as a whole with a glass of water; do not chew or break it.

MEFRAN SPAS TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). MEFRAN SPAS TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, MEFRAN SPAS TABLET helps in relieving pain.

MEFRAN SPAS TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, MEFRAN SPAS TABLET helps in relieving pain.
Store in a cool and dry place away from sunlight
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache
  • Dry mouth
  • Weakness
  • Nervousness
  • Loss of appetite
Do not take more than the prescribed dose of MEFRAN SPAS TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Do not take MEFRAN SPAS TABLET if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. MEFRAN SPAS TABLET may cause dizziness and drowsiness, so drive only if you are alert. MEFRAN SPAS TABLET should not be given to children as safety has not been established. Avoid consuming alcohol with MEFRAN SPAS TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking MEFRAN SPAS TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with MEFRAN SPAS TABLET unless prescribed. 

verifiedApollotooltip
DicyclominePramlintide
Critical
DicyclominePotassium chloride
Critical

Drug-Drug Interactions

DicyclominePramlintide
Critical
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of Pramlintide with MEFRAN SPAS TABLET can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium chloride
Critical
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of MEFRAN SPAS TABLET with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with MEFRAN SPAS TABLET:
Taking MEFRAN SPAS TABLET and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Mefenamic acidMeloxicam
Critical
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of MEFRAN SPAS TABLET with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with MEFRAN SPAS TABLET:
Coadministration of MEFRAN SPAS TABLET with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DicyclomineTopiramate
Severe
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of MEFRAN SPAS TABLET with Topiramate may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use MEFRAN SPAS TABLET and Topiramate together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue the medication without consulting a doctor.
DicyclomineZonisamide
Severe
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of MEFRAN SPAS TABLET with Zonisamide may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use MEFRAN SPAS TABLET and Zonisamide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue any medication without consulting a doctor.
DicyclomineSecretin
Severe
How does the drug interact with MEFRAN SPAS TABLET:
Co-administration of Secretin human with MEFRAN SPAS TABLET may decrease the therapeutic efficacy of Secretin human.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Secretin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
Mefenamic acidNaproxen
Severe
How does the drug interact with MEFRAN SPAS TABLET:
Coadministration of MEFRAN SPAS TABLET with Naproxen can increase the risk or severity of stomach bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking MEFRAN SPAS TABLET with Naproxen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidBaricitinib
Severe
How does the drug interact with MEFRAN SPAS TABLET:
Using MEFRAN SPAS TABLET and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of MEFRAN SPAS TABLET with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes, instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

  • Stay hydrated, drink plenty of water.

No
ANTISPASMODICS

MEFRAN SPAS TABLET Substitute

Substitutes safety advice
  • Meftal-Spas Tablet 10's

    4.68per tablet
  • Dysmen Tablet 10's

    6.35per tablet
  • SPASMOFIRST TABLET 10'S

    by AYUR

    9.32per tablet
  • Spasmonil Plus Tablet 10's

    2.93per tablet
  • Cyclopam-MF Tablet 10's

    4.37per tablet
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FAQs

MEFRAN SPAS TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.
MEFRAN SPAS TABLET contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.
Diarrhoea might be a side-effect of MEFRAN SPAS TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.
MEFRAN SPAS TABLET is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.
Dry mouth could be a side-effect of MEFRAN SPAS TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.
MEFRAN SPAS TABLET should not be taken for more than 7days. Do not take MEFRAN SPAS TABLET for longer durations as it might increase the risk of heart problems and stomach bleeding.
MEFRAN SPAS TABLET is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take MEFRAN SPAS TABLET only as prescribed, and do not overdose.
No, MEFRAN SPAS TABLET may not cause infertility. Consult the doctor if you have any concerns.
Yes, it is safe to use MEFRAN SPAS TABLET during periods if prescribed by the doctor. It helps relieve period cramps.
MEFRAN SPAS TABLET may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking this medication.
MEFRAN SPAS TABLET starts working within an hour.
Do not take MEFRAN SPAS TABLET on an empty stomach. Take MEFRAN SPAS TABLET with meals or immediately after meals to prevent stomach upset.
No, MEFRAN SPAS TABLET is recommended for headaches and toothache. It is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.
Yes, MEFRAN SPAS TABLET can be taken with food or immediately after food.
No, MEFRAN SPAS TABLET does not stop menstruation. It does not affect the menstrual bleeding or the duration of periods. It only helps relieve menstrual cramps.
MEFRAN SPAS TABLET should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
MEFRAN SPAS TABLET may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.
Yes, MEFRAN SPAS TABLET is a painkiller. It contains Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). MEFRAN SPAS TABLET helps relieve abdominal pain, colicky pain, and period pains.
Yes, MEFRAN SPAS TABLET is safe if taken in the dose and duration prescribed by the doctor.
MEFRAN SPAS TABLET is not recommended for children as safety and effectiveness were not established.
MEFRAN SPAS TABLET should be used during pregnancy only if prescribed by the doctor. Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
MEFRAN SPAS TABLET may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Talk to your doctor if these side effects persist or worsen.
INDIA
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - MEF0024

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