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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Mefcomb-Forte Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. It contains Mefenamic acid and Paracetamol which helps reduce mild to moderate pain and inflammation at the injured or damaged site. It may cause common side effects such as nausea, vomiting, indigestion, heartburn, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Kanstride Biolabs

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Mefcomb-Forte Tablet

Mefcomb-Forte Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Mefcomb-Forte Tablet contains two drugs, Mefenamic acid and Paracetamol. Mefcomb-Forte Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Mefcomb-Forte Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Mefcomb-Forte Tablet may cause common side effects such as nausea, vomiting, indigestion, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Mefcomb-Forte Tablet may cause dizziness, so drive only if you are alert. Avoid consuming alcohol with Mefcomb-Forte Tablet as it could lead to increased dizziness and may increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Mefcomb-Forte Tablet

Treatment of Pain, inflammation, osteoarthritis, and rheumatoid arthritis.

Directions for Use

Swallow Mefcomb-Forte Tablet as a whole with a glass of water; do not chew or break the tablet/capsule.

Medicinal Benefits

Mefcomb-Forte Tablet contains two Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Mefenamic acid and Paracetamol. Mefcomb-Forte Tablet is used to treat pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. Mefcomb-Forte Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandin. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

How Mefcomb-Forte Tablet Works

Mefcomb-Forte Tablet contains two drugs, Mefenamic acid and Paracetamol. Mefcomb-Forte Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mefcomb-Forte Tablet

  • Indigestion
  • Nausea
  • Diarrhoea
  • Heartburn
  • Vomiting

What if I have taken an overdose of Mefcomb-Forte Tablet

Do not take more than the prescribed dose of Mefcomb-Forte Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Mefcomb-Forte Tablet if you are allergic to any of its contents; if you have severe heart, kidney or liver failure; or if you have suffered bleeding problems such as bleeding from the stomach or bowels while taking painkillers or if you have peptic ulcers or inflammatory bowel disease. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, dehydration, asthma, gastrointestinal bleeding, ulceration, perforation of the stomach and intestine, or liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Mefcomb-Forte Tablet may cause dizziness, so drive only if you are alert. Stop taking Mefcomb-Forte Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Mefcomb-Forte Tablet unless prescribed by the doctor.

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Mefcomb-Forte Tablet:
Co-administration of Mefcomb-Forte Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Mefcomb-Forte Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Mefcomb-Forte Tablet:
Coadministration of Mefcomb-Forte Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Mefcomb-Forte Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidNaproxen
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Coadministration of Mefcomb-Forte Tablet with Naproxen can increase the risk or severity of stomach bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Mefcomb-Forte Tablet with Naproxen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidHuman immunoglobulin
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Taking Human immunoglobulin with Mefcomb-Forte Tablet, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Mefcomb-Forte Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidTacrolimus
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Coadministration of Mefcomb-Forte Tablet with Tacrolimus can increase the risk of kidney problems.

How to manage the interaction:
Taking Mefcomb-Forte Tablet with Tacrolimus together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Coadministration of Mefcomb-Forte Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Mefcomb-Forte Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidTeriflunomide
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Teriflunomide may cause liver damage and taking it with Mefcomb-Forte Tablet may increase that risk.

How to manage the interaction:
Although taking Mefcomb-Forte Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away - liver problems, fever, feeling cold, pain in your joints, swelling, bruises, rash, itchy skin, not feeling hungry, feeling tired, feeling sick, throwing up, dark urine, or bleeding. Do not discontinue any medications without consulting a doctor.
Mefenamic acidApixaban
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Mefcomb-Forte Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Mefcomb-Forte Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
Mefenamic acidDalteparin
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Combining Mefcomb-Forte Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Dalteparin and Mefcomb-Forte Tablet together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any signs like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Mefenamic acidBaricitinib
Severe
How does the drug interact with Mefcomb-Forte Tablet:
Using Mefcomb-Forte Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Mefcomb-Forte Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Mefcomb-Forte Tablet Substitute

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mefcomb-Forte Tablet as it may cause increased dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor before taking Mefcomb-Forte Tablet ; your doctor will decide whether Mefcomb-Forte Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Mefcomb-Forte Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Please consult your doctor. Your doctor will prescribe the dose and duration based on your child's condition.

FAQs

Mefcomb-Forte Tablet is used for the treatment of pain, inflammation, migraine headache, period pain, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis.
Mefcomb-Forte Tablet blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.
Mefcomb-Forte Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is tenderness and swelling in the joints.
Avoid taking Mefcomb-Forte Tablet if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.
Diarrhoea might be a side-effect of Mefcomb-Forte Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience severe diarrhea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Mefcomb-Forte Tablet is used to relieve menstrual (period) pain and management of excessively heavy periods. Take Mefcomb-Forte Tablet only as prescribed by the doctor.
Mefcomb-Forte Tablet is generally prescribed for short-term use. Do not take Mefcomb-Forte Tablet for longer durations as it might increase the risk of kidney problems and stomach bleeding.

Country of origin

India

Manufacturer/Marketer address

4930, New Sunny Enclave, Sec-125, Mohali
Other Info - MEF0243

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