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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mecotrip Tablet is used to treat neuropathic pain (nerve pain). It works by lowering the pain signals to the brain and promoting the synthesis of myelin, a substance that protects nerve fibres and rejuvenates injured nerve cells. In some cases, this medicine may cause side effects such as constipation, dizziness, dry mouth, feeling sleepy, and headache.
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Manufacturer/Marketer :

Solis Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mecotrip Tablet

Mecotrip Tablet is used to manage neuropathic pain due to damaged nerves. Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system. The pain could be intermittent or continuous, like a prickling, stabbing, tingling, or burning sensation.

Mecotrip Tablet is a combination of two drugs: Amitriptyline and Methylcobalamin. Amitriptyline belongs to a class of medications known as tricyclic antidepressants, and it works by boosting serotonin levels in the brain. This can make you feel better. This can also alter how your nerves receive pain signals, causing pain to subside. Methylcobalamin is a vitamin B derivative that promotes the synthesis of myelin, which protects nerve fibres and rejuvenates injured nerve cells. They work together to alleviate neuropathic pain (pain from damaged nerves).

Take Mecotrip Tablet as prescribed by your doctor. Depending on your medical condition, you are advised to take Mecotrip Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects such as constipation, dizziness, dry mouth, feeling sleepy, difficulty peeing, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not take Mecotrip Tablet if you have had an allergic reaction to Mecotrip Tablet or any ingredients in it. Tell your doctor if you're pregnant, trying to get pregnant, or breastfeeding. Mecotrip Tablet is generally not recommended in pregnancy and breastfeeding. Your doctor will only prescribe Mecotrip Tablet for your pain while you're pregnant or breastfeeding if the benefits of taking medicine outweigh the risks. Mecotrip Tablet may cause side effects like Light-headedness or dizziness, which may affect your concentration ability. Hence, it is recommended not to drive or operate machinery until you are mentally alert. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Mecotrip Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Mecotrip Tablet

Treatment of Neuropathic pain

Directions for Use

Swallow Mecotrip Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mecotrip Tablet is a combination of two drugs: Amitriptyline and Methylcobalamin. Amitriptyline belongs to a class of medications known as tricyclic antidepressants. Antidepressants are considered to function by boosting serotonin levels in the brain, making you feel better. And also, these can alter how your nerves receive pain signals, causing pain to subside. Methylcobalamin is a vitamin B derivative that promotes the synthesis of myelin, which protects nerve fibres and rejuvenates injured nerve cells. They work together to alleviate neuropathic pain (pain from damaged nerves).

How Mecotrip Tablet Works

Mecotrip Tablet is a combination of two drugs: Amitriptyline and Methylcobalamin. Amitriptyline belongs to a class of medications known as tricyclic antidepressants, and it works by boosting serotonin levels in the brain. This can make you feel better. This can also alter how your nerves receive pain signals, causing pain to subside. Methylcobalamin is a vitamin B derivative that promotes the synthesis of myelin, which protects nerve fibres and rejuvenates injured nerve cells. They work together to alleviate neuropathic pain (pain from damaged nerves).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mecotrip Tablet

  • Constipation

  • Dizziness

  • Dry Mouth

  • Feeling Sleepy

  • Difficulty Peeing

  • Headache

  • Appetite changes

What if I have taken an overdose of Mecotrip Tablet

Take Mecotrip Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Mecotrip Tablet if you have allergic reactions to Mecotrip Tablet or any ingredients. Tell your doctor if you're pregnant, trying to get pregnant, or breastfeeding. Mecotrip Tablet is generally not recommended in pregnancy and breastfeeding. Your doctor will only prescribe Mecotrip Tablet for your pain while pregnant or breastfeeding if the benefits of taking medicine outweigh the risks. Mecotrip Tablet may cause side effects like Light-headedness or dizziness, affecting your concentration. Hence, it is recommended not to drive or operate machinery until you are mentally alert. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol with Mecotrip Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, a blood disorder called porphyria, epilepsy, glaucoma, or suicidal tendency.

Drug-Drug Interactions

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AmitriptylineSparfloxacin
Critical
AmitriptylineProcarbazine
Critical

Drug-Drug Interactions

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AmitriptylineSparfloxacin
Critical
How does the drug interact with Mecotrip Tablet 10's:
Combining Mecotrip Tablet 10's and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Mecotrip Tablet 10's with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineProcarbazine
Critical
How does the drug interact with Mecotrip Tablet 10's:
Using Mecotrip Tablet 10's together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Mecotrip Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Mecotrip Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylineSelegiline
Critical
How does the drug interact with Mecotrip Tablet 10's:
Co-administration of Mecotrip Tablet 10's together with Selegiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selegiline and Mecotrip Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Mecotrip Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylineTranylcypromine
Critical
How does the drug interact with Mecotrip Tablet 10's:
Taking Tranylcypromine with Mecotrip Tablet 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Mecotrip Tablet 10's together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
AmitriptylineBepridil
Critical
How does the drug interact with Mecotrip Tablet 10's:
Combining Mecotrip Tablet 10's and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Mecotrip Tablet 10's with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineRasagiline
Critical
How does the drug interact with Mecotrip Tablet 10's:
Using Mecotrip Tablet 10's together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Mecotrip Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Mecotrip Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylineSafinamide
Critical
How does the drug interact with Mecotrip Tablet 10's:
Using Mecotrip Tablet 10's together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Mecotrip Tablet 10's together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Mecotrip Tablet 10's. Do not discontinue any medications without consulting a doctor.
AmitriptylineDronedarone
Critical
How does the drug interact with Mecotrip Tablet 10's:
Combining Mecotrip Tablet 10's and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Mecotrip Tablet 10's with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Mecotrip Tablet 10's:
Combining Mecotrip Tablet 10's and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Mecotrip Tablet 10's with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Mecotrip Tablet 10's:
Mecotrip Tablet 10's and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Mecotrip Tablet 10's and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Nutritional deficits can cause neuropathy symptoms. Choose foods high in nutrients, such as fruits, vegetables, and whole grains.

  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being. Saturated fat in fatty meats and dairy products has been linked to inflammation and an increased risk of type 2 diabetes.

  • Elevated blood sugar levels are linked to various chronic health problems, including diabetic peripheral neuropathy. Increase Omega–3 fatty acids, Fiber, and Antioxidants such as flaxseeds, fruits, vegetables, nuts, and beans to help you maintain a healthy blood sugar level and control your diabetes.

  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).

  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

CENTRAL NERVOUS SYSTEM AGENTS

Mecotrip Tablet Substitute

Substitutes safety advice
  • Amicobal 10/1500 Tablet 15's

    15.57per tablet
  • Amnuring 10 Tablet 10's

    by AYUR

    16.38per tablet
  • Meaxon AT Tablet 10's

    by AYUR

    13.50per tablet
  • Joycobal AT Tablet 10's

    14.40per tablet
  • Joycobal AT Tablet 15's

    16.20per tablet
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Alcohol

Caution

It is unclear whether alcohol can be taken while using this medication. However, as a precautionary measure, it is best to avoid alcohol while taking medication.

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Pregnancy

Caution

Mecotrip Tablet is generally not recommended in pregnancy. Your doctor will only prescribe Mecotrip Tablet for your pain while you're pregnant if the benefits of taking medicine outweigh the risks.

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Breast Feeding

Caution

Mecotrip Tablet is generally not recommended in breastfeeding. Your doctor will only prescribe Mecotrip Tablet for your pain while you're breastfeeding if the benefits of taking medicine outweigh the risks.

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Driving

Caution

Mecotrip Tablet may cause side effects like Light-headedness or dizziness, affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Limited information was available for the use of Mecotrip Tablet in patients with liver impairment. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of Mecotrip Tablet in patients with Kidney impairment. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Limited information was available for the use of Mecotrip Tablet in paediatric patients. Please consult the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

FAQs

Mecotrip Tablet is used to manage neuropathic pain due to damaged nerves.
Mecotrip Tablet is a combination of two drugs: Amitriptyline and Methylcobalamin. Amitriptyline belongs to a class of medications known as tricyclic antidepressants. Antidepressants are considered to function by boosting serotonin levels in the brain, making you feel better. And also, these can alter how your nerves receive pain signals, causing pain to subside. Methylcobalamin is a vitamin B derivative that promotes myelin synthesis, a material that protects nerve fibres and rejuvenates injured nerve cells. They work together to alleviate neuropathic pain (pain from damaged nerves).
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
Do not discontinue Mecotrip Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Mecotrip Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mecotrip Tablet ; your doctor will reduce the dose gradually.
Mecotrip Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Country of origin

India

Manufacturer/Marketer address

Pl.No. 44-34-24, Beside Chekkadurai Building, Nandgiri Nagar, Akkayapallam, Visakhapatnam, Andhra Pradesh, 530016, India
Other Info - MEC0641

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