MDD XR Plus 50 Tablet belongs to a group of medicines called 'antidepressants'. It is used in the treatment of depression. Depression is a common mood disorder which negatively affects a person's daily life, described as feelings of sadness, loss, or anger. Depression symptoms can vary from mild to severe and include sadness, thoughts of death or suicide, loss of interest, weight loss or gain unrelated to dieting, trouble sleeping, loss of energy, feeling worthless or guilty, and difficulty thinking.

MDD XR Plus 50 Tablet is a combination of two drugs: clonazepam and desvenlafaxine. Clonazepam (benzodiazepine) works by increasing levels of a calming chemical, gamma-amino-butyric acid (GABA), in your brain. Desvenlafaxine (selective serotonin and norepinephrine reuptake inhibitors (SNRIs)) works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the brain that helps to maintain mental balance. Together, both of them help to elevate mood and treat depression.

Take MDD XR Plus 50 Tablet with or without food. The tablet form should be swallowed as a whole with a glass of water, do not chew or crush the tablet. In some cases, you may experience common side effects such as nausea, tiredness, constipation, confusion, insomnia (difficulty in sleeping), memory impairment, uncoordinated body movements, low sexual desire, depression, erectile dysfunction, and ejaculation disorder. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking MDD XR Plus 50 Tablet for as long as your doctor has prescribed. Do not take MDD XR Plus 50 Tablet if you are pregnant or breastfeeding unless specified by the doctor. MDD XR Plus 50 Tablet causes drowsiness, and sleepiness, do not drive unless you are alert. MDD XR Plus 50 Tablet should not be given to children and adolescents aged 18 years to treat depression. MDD XR Plus 50 Tablet is habit-forming so take it only if prescribed by a doctor. Avoid consuming alcohol with MDD XR Plus 50 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

MDD XR Plus 50 Tablet belongs to a group of medicines called 'antidepressants', containing clonazepam and desvenlafaxine. It is used in the treatment of depression. It improves mood, helps relieve anxiety and tension, and helps you sleep better. It also prevents extreme mood changes and increases your energy level, so you do not feel low. Clonazepam increases levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Desvenlafaxine (selective serotonin and norepinephrine reuptake inhibitors (SNRIs)) works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the brain that helps to maintain mental balance. Together, both of them help to elevate mood and treat depression.

• Headache
• Nausea
• Tiredness
• Dry mouth
• Constipation
• Confusion
• Insomnia (difficulty in sleeping)
• Memory impairment
• Ejaculation disorder
• Difficulty in urination
• Uncoordinated body movements
• Depression
• Erectile dysfunction
• Low sexual desire

Do not take MDD XR Plus 50 Tablet if you are allergic to any ingredients present in it. Inform your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or pain medication. Talk to your doctor if you have a history of seizures, bipolar disorder, suicide attempts, or schizophrenia. Patients with liver diseases, diabetes, heart disease, lung disease, and bleeding disorders should use MDD XR Plus 50 Tablet with caution. Please do not stop the treatment abruptly, as it can cause withdrawal reactions. MDD XR Plus 50 Tablet is not recommended for children and adolescents under 18 years of age as it increases suicidal tendencies in this population. MDD XR Plus 50 Tablet is habit-forming so take it only if prescribed by a doctor. Consult your doctor immediately if you experience suicidal thoughts like killing or harming yourself while on this medication. Do not take MDD XR Plus 50 Tablet if you are pregnant or breastfeeding unless prescribed. MDD XR Plus 50 Tablet causes drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with MDD XR Plus 50 Tablet as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions: MDD XR Plus 50 Tablet may have interaction with pain killers (tramadol, aspirin, acetaminophen, pethidine), narcotic pain relievers (morphine, codeine), blood thinners (warfarin), cholesterol medications (pravastatin), fits medicine (phenobarbital, phenytoin, sodium valproate, carbamazepine), anti-depression medication (aripiprazole, escitalopram), blood pressure medications (metoprolol), medications to treat stomach problems (cimetidine).

Drug-Food Interactions: Avoid consuming alcohol along with MDD XR Plus 50 Tablet as it may increase the sedative effects, and one can also experience impairment in thinking and judgment.

Drug-Disease Interactions: MDD XR Plus 50 Tablet may interact with disease conditions such as heart problems, acute alcohol intoxication, epilepsy, glaucoma, renal/liver disease, respiratory depression, and drug dependency.

• TRAMADOL
• ASPIRIN
• ACETAMINOPHEN
• PETHIDINE
• MORPHINE
• CODEINE
• PRAVASTATIN
• PHENOBARBITAL
• PHENYTOIN
• SODIUM VALPROATE
• CARBAMAZEPINE
• ARIPIPRAZOLE
• ESCITALOPRAM
• METOPROLOL
• CIMETIDINE

• Maintain a healthy and well-balanced diet. 
• Do not take stress as it may aggravate your condition.
• Limit alcohol intake and quit smoking.
• Engage in social activities frequently as it may improve self-esteem and confidence. 
• Limit caffeine intake.
• Maintaining a healthy diet and exercising regularly helps improve overall health and boost self-esteem.
• Regularly attend therapy sessions.
• Perform meditation and yoga. This helps in relieving stress and provides relaxation.
• Follow a regular sleep pattern to improve the amount and quality of sleep you get.
• Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
• Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help properly maintain neurotransmitters. 
• Complex carbohydrates help stimulate serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
• Exercising helps in the production of the body’s natural antidepressants. It also helps relieve stress, improve mood, boost self-esteem, and provide restful sleep.
• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

• MDD XR Plus 50 Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
• An abrupt stoppage of MDD XR Plus 50 Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
• MDD XR Plus 50 Tablet is habit-forming so take it only if prescribed by a doctor.
• Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.
• MDD XR Plus 50 Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor about changing/replacing the medicine with safer alternatives.
• To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.

Depression: It is a mood disorder characterized by sadness, unhappiness, anger, hopelessness, or loss that interferes with a person's daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions.