MDD XR 50 Tablet is used to treat a major depressive disorder (depression). Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking.
 
MDD XR 50 Tablet contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression. 
 
You are advised to take MDD XR 50 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking MDD XR 50 Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving as MDD XR 50 Tablet may cause sleepiness and dizziness. MDD XR 50 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with MDD XR 50 Tablet as it could lead to increased sleepiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

MDD XR 50 Tablet belongs to a group of antidepressant medicines indicated for the treatment of a major depressive disorder. MDD XR 50 Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps in regulating mood, and treats depression. 

• Nausea
• Dizziness 
• Insomnia (sleeplessness)
• Constipation
• Sleepiness 
• Loss of appetite 
• Anxiety 
• Sweating
• Erectile dysfunction

Do not take MDD XR 50 Tablet if you are allergic to any of its contents; if you are taking linezolid, intravenous methylene blue, other serotonergic agents, monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days. Inform your doctor before taking MDD XR 50 Tablet if you have heart problems, hypotension, bipolar disorder, glaucoma, epilepsy, lung or breathing problems, bleeding problems, or low sodium levels in the blood. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. MDD XR 50 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with MDD XR 50 Tablet as it could lead to increased sleepiness and dizziness. 

Drug-Drug Interactions: MDD XR 50 Tablet may interact with antipsychotic (aripiprazole, lurasidone, quetiapine), CNS stimulant (amphetamine/dextroamphetamine, phentermine, lisdexamfetamine), an antidepressant (amitriptyline, bupropion, duloxetine, escitalopram, sertraline, trazodone, venlafaxine), anti-convulsant (clonazepam, lamotrigine, pregabalin), skeletal muscle relaxant (cyclobenzaprine), pain killer (ibuprofen, tramadol), anti-anxiety (alprazolam), an antihistamine (cetirizine).

Drug-Food Interactions: Avoid consuming alcohol along with MDD XR 50 Tablet as it may increase dizziness and sleepiness. Avoid taking St. John’s wort (herbal supplement used to treat depression) along with MDD XR 50 Tablet as it may cause serotonin syndrome.

Drug-Disease Interactions: Inform your doctor if you have urinary tract obstruction, glaucoma, high blood pressure, seizures, renal disease, mania, or hyponatremia (low levels of sodium).

• ARIPIPRAZOLE
• LURASIDONE
• QUETIAPINE
• AMPHETAMINE
• DEXTROAMPHETAMINE
• AMITRIPTYLINE
• BUPROPION
• DULOXETINE
• ESCITALOPRAM
• SERTRALINE
• TRAZODONE
• VENLAFAXINE
• CLONAZEPAM
• LAMOTRIGINE
• PREGABALIN
• CYCLOBENZAPRINE
• IBUPROFEN
• TRAMADOL
• ALPRAZOLAM
• CETIRIZINE
• PHENTERMINE
• LISDEXAMFETAMINE

• Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

• Regularly attend therapy sessions.

• Perform meditation and yoga. This helps in relieving stress and provides relaxation.

• Follow a regular sleep pattern to improve the amount and quality of sleep you get.

• Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

• Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

• Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

• Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improves mood, boosts self-esteem, and provides restful sleep.

• Avoid smoking and alcohol consumption.

• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

• Do not stop taking MDD XR 50 Tablet suddenly as it might cause withdrawal symptoms.

• Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself.

• Talk to your doctor right away if you notice any unusual bleeding or bruising.

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression.