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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mdd Xr 25mg Tablet is used to treat a major depressive disorder (depression). It contains Desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression. In some cases, you may experience certain common side effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DESVENLAFAXINE-25MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mdd Xr 25mg Tablet

Mdd Xr 25mg Tablet is used to treat a major depressive disorder (depression). Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking.
 
Mdd Xr 25mg Tablet contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression. 
 
You are advised to take Mdd Xr 25mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking Mdd Xr 25mg Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving as Mdd Xr 25mg Tablet may cause sleepiness and dizziness. Mdd Xr 25mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mdd Xr 25mg Tablet as it could lead to increased sleepiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Mdd Xr 25mg Tablet

Treatment of Depression

Directions for Use

Take Mdd Xr 25mg Tablet with or without food. Swallow Mdd Xr 25mg Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Mdd Xr 25mg Tablet belongs to a group of antidepressant medicines indicated for the treatment of a major depressive disorder. Mdd Xr 25mg Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps in regulating mood, and treats depression. 

How Mdd Xr 25mg Tablet Works

Mdd Xr 25mg Tablet contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mdd Xr 25mg Tablet

  • Nausea
  • Dizziness 
  • Insomnia (sleeplessness)
  • Constipation
  • Sleepiness 
  • Loss of appetite 
  • Anxiety 
  • Sweating
  • Erectile dysfunction

What if I have taken an overdose of Mdd Xr 25mg Tablet

Do not take more than the prescribed dose of Mdd Xr 25mg Tablet as it may cause overdose. The symptoms of overdose include drowsiness, coma, seizures, vomiting, agitation, hallucinations, fever, sweating, severe muscle stiffness or twitching, confusion, fast heartbeat, shivering, loss of coordination, fast/slow/irregular heartbeat, nausea, vomiting, or diarrhea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Mdd Xr 25mg Tablet if you are allergic to any of its contents; if you are taking linezolid, intravenous methylene blue, other serotonergic agents, monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days. Inform your doctor before taking Mdd Xr 25mg Tablet if you have heart problems, hypotension, bipolar disorder, glaucoma, epilepsy, lung or breathing problems, bleeding problems, or low sodium levels in the blood. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Mdd Xr 25mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mdd Xr 25mg Tablet as it could lead to increased sleepiness and dizziness. 

Drug-Drug Interactions

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DesvenlafaxineRasagiline
Critical
DesvenlafaxineSafinamide
Critical

Drug-Drug Interactions

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DesvenlafaxineRasagiline
Critical
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Taking rasagiline with Mdd Xr 25mg Tablet 15's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Mdd Xr 25mg Tablet 15's with Rasagiline together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DesvenlafaxineSafinamide
Critical
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Taking Safinamide with Mdd Xr 25mg Tablet 15's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Mdd Xr 25mg Tablet 15's with Safinamide is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
DesvenlafaxineTranylcypromine
Critical
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Taking tranylcypromine with Mdd Xr 25mg Tablet 15's might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Tranylcypromine and Mdd Xr 25mg Tablet 15's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DesvenlafaxineIsocarboxazid
Critical
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Combining Isocarboxazid and Mdd Xr 25mg Tablet 15's might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Isocarboxazid and Mdd Xr 25mg Tablet 15's together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DesvenlafaxineProcarbazine
Critical
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Combining Procarbazine and Mdd Xr 25mg Tablet 15's can increase the risk of a rare but serious condition called the serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Procarbazine and Mdd Xr 25mg Tablet 15's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. you should wait at least 14 days after stopping isocarboxazid before you start treatment with Mdd Xr 25mg Tablet 15's and do not discontinue any medications without first consulting your doctor.
DesvenlafaxineCitalopram
Severe
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Co-administration of citalopram and Mdd Xr 25mg Tablet 15's might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of citalopram and Mdd Xr 25mg Tablet 15's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DesvenlafaxineDextromethorphan
Severe
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Co-administration of Dextromethorphan and Mdd Xr 25mg Tablet 15's might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Dextromethorphan and Mdd Xr 25mg Tablet 15's, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizure (fits), confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramps, and diarrhea, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.
DesvenlafaxineTramadol
Severe
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Combining Mdd Xr 25mg Tablet 15's with Tramadol can increase the risk of serotonin syndrome.

How to manage the interaction:
There may be a possibility of interaction between Tramadol and Mdd Xr 25mg Tablet 15's, but it can be taken if prescribed by a doctor. If you experience symptoms like confusion, hallucinations, seizures, or a fast heartbeat, fever, sweating, blurred vision, muscle spasms, tremors, stomach cramps, nausea, vomiting, diarrhea, or if you've had a head injury, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DesvenlafaxineBupropion
Severe
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Co-administration of Bupropion with Mdd Xr 25mg Tablet 15's may increase the risk or severity of seizures.

How to manage the interaction:
Co-administration of bupropion along with Mdd Xr 25mg Tablet 15's can lead to an interaction, it can be taken if recommended by a doctor. Avoid or limit tasks that need mental attention, such as driving or operating dangerous machinery while taking them. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, involuntary movements, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DesvenlafaxineClomipramine
Severe
How does the drug interact with Mdd Xr 25mg Tablet 15's:
Coadministration of Mdd Xr 25mg Tablet 15's with clomipramine might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking clomipramine and Mdd Xr 25mg Tablet 15's together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improves mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Mdd Xr 25mg Tablet Substitute

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    6.30per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mdd Xr 25mg Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Caution

Mdd Xr 25mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Mdd Xr 25mg Tablet may pass into breastmilk. Consult your doctor before taking Mdd Xr 25mg Tablet your doctor will decide whether Mdd Xr 25mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Mdd Xr 25mg Tablet causes sleepiness and dizziness. Do not drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Mdd Xr 25mg Tablet should not be given to children as safety and effectiveness have not been established.

FAQs

Mdd Xr 25mg Tablet is used to treat a major depressive disorder (depression).
Mdd Xr 25mg Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain, which maintain mental balance, thereby regulating mood that treats depression.
Do not discontinue Mdd Xr 25mg Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Mdd Xr 25mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mdd Xr 25mg Tablet .
Mdd Xr 25mg Tablet may cause decreased sex drive (libido) and problems with ejaculation and orgasm. Consult your doctor if you have any concerns regarding this.
Hypertension should be controlled before starting treatment with Mdd Xr 25mg Tablet . Therefore, consult your doctor if you have high blood pressure. Regular monitoring of blood pressure levels is advised while taking Mdd Xr 25mg Tablet .
Mdd Xr 25mg Tablet may increase the chances of bleeding and bruising. The risk increases when Mdd Xr 25mg Tablet is taken along with painkillers and blood thinners. Consult your doctor if you notice unusual bleeding or bruising.
When taken along with other medicines, Mdd Xr 25mg Tablet may cause a rare but potentially life-threatening condition called serotonin syndrome. This condition causes changes in how the brain, blood vessels, muscles and digestive system work. Avoid taking Mdd Xr 25mg Tablet along with MAOIs (used to treat depression), linezolid, intravenous methylene blue and other serotonergic agents.
Mdd Xr 25mg Tablet may dilate your pupils (widen the dark centres of your eyes). This can trigger a glaucoma attack. Before taking Mdd Xr 25mg Tablet , consult your doctor if you have glaucoma.
Mdd Xr 25mg Tablet may cause seizures. If you’ve ever had a seizure, tell your doctor before taking Mdd Xr 25mg Tablet .
Many people have sexual side effects when using antidepressants. Working together with your doctor will help you find a solution that addresses both your mental and sexual wellness.
You may have to take Mdd Xr 25mg Tablet for several weeks before you begin to feel better.
Mdd Xr 25mg Tablet can begin lowering anxiety symptoms in as little as one week, according to one clinical study. Generally, you'll start to feel the full effects after taking it for eight weeks.
Although Mdd Xr 25mg Tablet is only officially allowed to treat depression, doctors frequently prescribe it to treat anxiety as well.
Take Mdd Xr 25mg Tablet exactly as prescribed by your healthcare practitioner. Take Mdd Xr 25mg Tablet once a day, about the same time every day. Mdd Xr 25mg Tablet can be taken with or without food. Swallow Mdd Xr 25mg Tablet pills whole and with drink.
It should be swallowed whole with fluid and not divided, crushed, chewed, or dissolved.
Mdd Xr 25mg Tablet works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance. Thus, it helps to treat depression.
Mdd Xr 25mg Tablet doesn't typically cause weight gain for most people. In very rare case, people taking it experience weight changes (gain or loss) of less than 2 kgs.
Mdd Xr 25mg Tablet may cause sexual dysfunction; however, men are more affected than women. If it happens to you, please seek medical attention from your doctor.
Common side effects of Mdd Xr 25mg Tablet may include nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - MDD0005

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