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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
MDD XR 100 Tablet is used to treat a major depressive disorder (depression). It contains Desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression. In some cases, you may experience certain common side effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About MDD XR 100 Tablet

MDD XR 100 Tablet is used to treat a major depressive disorder (depression). Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking.
 
MDD XR 100 Tablet contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps regulate mood, and treats depression. 
 
You are advised to take MDD XR 100 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking MDD XR 100 Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving as MDD XR 100 Tablet may cause sleepiness and dizziness. MDD XR 100 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with MDD XR 100 Tablet as it could lead to increased sleepiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of MDD XR 100 Tablet

Treatment of Depression

Medicinal Benefits

MDD XR 100 Tablet belongs to a group of antidepressant medicines indicated for the treatment of a major depressive disorder. MDD XR 100 Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance, helps in regulating mood, and treats depression. 

Directions for Use

Take MDD XR 100 Tablet with or without food. Swallow MDD XR 100 Tablet as a whole with a glass of water, do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MDD XR 100 Tablet

  • Nausea
  • Dizziness 
  • Insomnia (sleeplessness)
  • Constipation
  • Sleepiness 
  • Loss of appetite 
  • Anxiety 
  • Sweating
  • Erectile dysfunction

Drug Warnings

Do not take MDD XR 100 Tablet if you are allergic to any of its contents; if you are taking linezolid, intravenous methylene blue, other serotonergic agents, monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days. Inform your doctor before taking MDD XR 100 Tablet if you have heart problems, hypotension, bipolar disorder, glaucoma, epilepsy, lung or breathing problems, bleeding problems, or low sodium levels in the blood. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. MDD XR 100 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with MDD XR 100 Tablet as it could lead to increased sleepiness and dizziness. 

Drug Interactions

Drug-Drug Interactions: MDD XR 100 Tablet may interact with antipsychotic (aripiprazole, lurasidone, quetiapine), CNS stimulant (amphetamine/dextroamphetamine, phentermine, lisdexamfetamine), an antidepressant (amitriptyline, bupropion, duloxetine, escitalopram, sertraline, trazodone, venlafaxine), anti-convulsant (clonazepam, lamotrigine, pregabalin), skeletal muscle relaxant (cyclobenzaprine), pain killer (ibuprofen, tramadol), anti-anxiety (alprazolam), an antihistamine (cetirizine).

Drug-Food Interactions: Avoid consuming alcohol along with MDD XR 100 Tablet as it may increase dizziness and sleepiness. Avoid taking St. John’s wort (herbal supplement used to treat depression) along with MDD XR 100 Tablet as it may cause serotonin syndrome.

Drug-Disease Interactions: Inform your doctor if you have urinary tract obstruction, glaucoma, high blood pressure, seizures, renal disease, mania, or hyponatremia (low levels of sodium).

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • AMPHETAMINE
  • DEXTROAMPHETAMINE
  • AMITRIPTYLINE
  • BUPROPION
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • TRAZODONE
  • VENLAFAXINE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • CYCLOBENZAPRINE
  • IBUPROFEN
  • TRAMADOL
  • ALPRAZOLAM
  • CETIRIZINE
  • PHENTERMINE
  • LISDEXAMFETAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improves mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Do not stop taking MDD XR 100 Tablet suddenly as it might cause withdrawal symptoms.

  • Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself.

  • Talk to your doctor right away if you notice any unusual bleeding or bruising.

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking MDD XR 100 Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Caution

MDD XR 100 Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

MDD XR 100 Tablet may pass into breastmilk. Consult your doctor before taking MDD XR 100 Tablet your doctor will decide whether MDD XR 100 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

MDD XR 100 Tablet causes sleepiness and dizziness. Do not drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

MDD XR 100 Tablet should not be given to children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - MDD0004

Author Details

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FAQs

MDD XR 100 Tablet is used to treat a major depressive disorder (depression).
MDD XR 100 Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain, which maintain mental balance, thereby regulating mood that treats depression.
Do not discontinue MDD XR 100 Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking MDD XR 100 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking MDD XR 100 Tablet .
MDD XR 100 Tablet may cause decreased sex drive (libido) and problems with ejaculation and orgasm. Consult your doctor if you have any concerns regarding this.
Hypertension should be controlled before starting treatment with MDD XR 100 Tablet . Therefore, consult your doctor if you have high blood pressure. Regular monitoring of blood pressure levels is advised while taking MDD XR 100 Tablet .
MDD XR 100 Tablet may increase the chances of bleeding and bruising. The risk increases when MDD XR 100 Tablet is taken along with painkillers and blood thinners. Consult your doctor if you notice unusual bleeding or bruising.
When taken along with other medicines, MDD XR 100 Tablet may cause a rare but potentially life-threatening condition called serotonin syndrome. This condition causes changes in how the brain, blood vessels, muscles and digestive system work. Avoid taking MDD XR 100 Tablet along with MAOIs (used to treat depression), linezolid, intravenous methylene blue and other serotonergic agents.
MDD XR 100 Tablet may dilate your pupils (widen the dark centres of your eyes). This can trigger a glaucoma attack. Before taking MDD XR 100 Tablet , consult your doctor if you have glaucoma.
MDD XR 100 Tablet may cause seizures. If you’ve ever had a seizure, tell your doctor before taking MDD XR 100 Tablet .
Many people have sexual side effects when using antidepressants. Working together with your doctor will help you find a solution that addresses both your mental and sexual wellness.
You may have to take MDD XR 100 Tablet for several weeks before you begin to feel better.
MDD XR 100 Tablet can begin lowering anxiety symptoms in as little as one week, according to one clinical study. Generally, you'll start to feel the full effects after taking it for eight weeks.
Although MDD XR 100 Tablet is only officially allowed to treat depression, doctors frequently prescribe it to treat anxiety as well.
Take MDD XR 100 Tablet exactly as prescribed by your healthcare practitioner. Take MDD XR 100 Tablet once a day, about the same time every day. MDD XR 100 Tablet can be taken with or without food. Swallow MDD XR 100 Tablet pills whole and with drink.
It should be swallowed whole with fluid and not divided, crushed, chewed, or dissolved.
MDD XR 100 Tablet works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance. Thus, it helps to treat depression.
MDD XR 100 Tablet doesn't typically cause weight gain for most people. In very rare case, people taking it experience weight changes (gain or loss) of less than 2 kgs.
MDD XR 100 Tablet may cause sexual dysfunction; however, men are more affected than women. If it happens to you, please seek medical attention from your doctor.
Common side effects of MDD XR 100 Tablet may include nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders.

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