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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Match Q 500mg Tablet is used to treat malaria. It gives a degree of protection against malaria when people travel to areas where malaria cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. It is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). It contains Chloroquine, which kills the organisms causing malaria and amoebiasis. It may cause common side effects such as vomiting, nausea, hair loss and itchy skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CHLOROQUINE-500MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Match Q 500mg Tablet

Match Q 500mg Tablet belongs to the class of medications called 'quinoline' primarily used to treat malaria. Match Q 500mg Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Match Q 500mg Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Match Q 500mg Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Match Q 500mg Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Match Q 500mg Tablet should be taken as prescribed by your doctor. The dose of Match Q 500mg Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Match Q 500mg Tablet include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Match Q 500mg Tablet, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Match Q 500mg Tablet on your own. Match Q 500mg Tablet is safe to use during pregnancy and breastfeeding. Prolonged use of Match Q 500mg Tablet may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Match Q 500mg Tablet

Treatment of Malaria, Intestinal amoebiasis, Rheumatoid arthritis.

Medicinal Benefits

Match Q 500mg Tablet falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Match Q 500mg Tablet contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Match Q 500mg Tablet is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

Side Effects of Match Q 500mg Tablet

  • Abnormal heart rhythm
  • Stomach pain
  • Nausea (being sick)
  • Diarrhoea
  • Loss of appetite
  • Headache
  • Skin rash
  • Liver problems

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Match Q 500mg Tablet does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Match Q 500mg Tablet. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Match Q 500mg Tablet cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Therapeutic Class

ANTI- MALARIALS

Diet & Lifestyle Advise

  • Always take Match Q 500mg Tablet with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

How Match Q 500mg Tablet Works

Match Q 500mg Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Match Q 500mg Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

What if I have taken an overdose of Match Q 500mg Tablet

Do not take more than the prescribed dose of Match Q 500mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

No serious interaction has been reported between alcohol and Match Q 500mg Tablet yet alcohol should be avoided with Match Q 500mg Tablet as it aggravates side effects.

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Pregnancy

Caution

Match Q 500mg Tablet should be used with caution and can only be used in pregnancy if recommended by the doctor.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Match Q 500mg Tablet as this medicine can pass into breast milk. A patient is advised to take this drug only on doctor's consultation.

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Driving

Caution

Match Q 500mg Tablet may cause blurred vision, so one should avoid driving or doing any activity that needs mental alertness. A patient is thus advised to take this drug only on doctor's consultation.

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Liver

Caution

Match Q 500mg Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Match Q 500mg Tablet.

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Kidney

Caution

Match Q 500mg Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Match Q 500mg Tablet.

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Children

Safe if prescribed

Match Q 500mg Tablet is safe to use in children, yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.

Country of origin

India
Other Info - MA75726

Author Details

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FAQs

Match Q 500mg Tablet is used to treat malaria. Match Q 500mg Tablet gives a degree of protection against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Match Q 500mg Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
Match Q 500mg Tablet works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.
The use of Match Q 500mg Tablet is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.
No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.
No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking Match Q 500mg Tablet is advised to consult a doctor and have regular check-ups cyclically.
There may be a risk of hemolysis in patients with G6PD deficiency while using Match Q 500mg Tablet. Doctor's consultation is mandatory before you start this medication.

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