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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Masnol Plus 10 Tablet SR is used to treat migraine. It contains Propranolol and Flunarizine which improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It effectively treats and reduces the severity and frequency of migraine headaches. Also, it is also used to treat vertigo (spinning sensation). It may cause common side effects such as dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Masson Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Masnol Plus 10 Tablet SR

Masnol Plus 10 Tablet SR is used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Masnol Plus 10 Tablet SR consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Masnol Plus 10 Tablet SR include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Masnol Plus 10 Tablet SR. Masnol Plus 10 Tablet SR may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Masnol Plus 10 Tablet SR if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Masnol Plus 10 Tablet SR as it could lead to increased drowsiness.

Uses of Masnol Plus 10 Tablet SR

Treatment of Migraine.

Medicinal Benefits

Masnol Plus 10 Tablet SR is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, as well as electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. 

Directions for Use

Swallow Masnol Plus 10 Tablet SR as a whole with a glass of water; do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Masnol Plus 10 Tablet SR

  • Weight gain
  • Slow heart rate
  • Tiredness
  • Depression
  • Drowsiness
  • Abnormal dreams
  • Cold extremities (hands and feet)

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Masnol Plus 10 Tablet SR. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Masnol Plus 10 Tablet SR. Avoid consuming alcohol along with Masnol Plus 10 Tablet SR as it could lead to increased dizziness and drowsiness.

Drug Interactions

Drug-Drug Interaction: Masnol Plus 10 Tablet SR may interact with mood disorder medicines (alprazolam, quetiapine, aripiprazole), drugs treating sleeping problems (zolpidem), respiratory drugs (diphenhydramine), antidepressants (sertraline, duloxetine, fluoxetine), and fits medicine (carbamazepine, phenytoin).

Drug-Food Interaction: Alcohol may cause dizziness and drowsiness when taken with Masnol Plus 10 Tablet SR.

Drug-Disease Interaction: Before using Masnol Plus 10 Tablet SR, let your doctor know if you have any liver, kidney or heart diseases, asthma, depression, muscle disorders, metabolic acidosis, diabetes, and alcohol dependency.

Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • QUETIAPINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • SERTRALINE
  • DULOXETINE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Masnol Plus 10 Tablet SR.
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Special Advise

  • Let your doctor know that you are taking Masnol Plus 10 Tablet SR if you are undergoing any medical tests.

  • Beta-blockers like Propranolol can mask hypoglycaemia symptoms (low blood sugar) or hyperthyroidism (high thyroid levels).

  • It is advised to inform your doctor if you have diabetes or thyroid disease before using Masnol Plus 10 Tablet SR.

  • Beta-blockers can also cause changes in serum lipid profiles. Patients with pre-existing hyperlipidaemia (high lipid levels) should be closely monitored if using Masnol Plus 10 Tablet SR.

Disease/Condition Glossary

Migraine: It is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Symptoms of migraine may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound. Migraine can be triggered by various factors like foods (eggs, tomatoes, onions, dairy products, wheat, pasta, citrus fruits, nitrites found in foods, alcohol, and red wine), hormonal changes, sleep changes, stress, loud noises, and medications.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Masnol Plus 10 Tablet SR. Alcohol intake, along with Masnol Plus 10 Tablet SR, may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to conceive before using Masnol Plus 10 Tablet SR.

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Breast Feeding

Caution

Please consult your doctor before taking Masnol Plus 10 Tablet SR if you are a lactating mother.

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Driving

Caution

Masnol Plus 10 Tablet SR may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

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Liver

Caution

Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.

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Kidney

Caution

Plasma clearance of Propranolol in Masnol Plus 10 Tablet SR is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Safe if prescribed

Masnol Plus 10 Tablet SR is safe to use for children below 12 years of age when prescribed by the doctor.

Country of origin

India
Other Info - MA57685

Author Details

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FAQs

Masnol Plus 10 Tablet SR belongs to the class of anti-migraine drugs used to treat migraine.
Masnol Plus 10 Tablet SR is a combination of two drugs: Propranolol and Flunarizine. Masnol Plus 10 Tablet SR treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.
Masnol Plus 10 Tablet SR may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.
Masnol Plus 10 Tablet SR does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.
Masnol Plus 10 Tablet SR is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Masnol Plus 10 Tablet SR if you have a medical history.
Your doctor will prescribe Masnol Plus 10 Tablet SR to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Masnol Plus 10 Tablet SR also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Masnol Plus 10 Tablet SR unless advised by your doctor.

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