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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:17 PM IST
Martidine 2.5 Tablet 10's is used to treat Parkinson's disease. It contains Procyclidine which relaxes the muscles and nerve impulses that control muscle functioning. In some cases, this medicine may cause side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, and drowsiness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Martinet Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Martidine 2.5 Tablet 10's

Martidine 2.5 Tablet 10's belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are movement problems. 
Martidine 2.5 Tablet 10's contains ‘Paliperidone’, which relaxes the muscles and nerve impulses that control muscle functioning. Besides this, Martidine 2.5 Tablet 10's also balances chemical messengers called neurotransmitters in our brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 
You can take Martidine 2.5 Tablet 10's with food to prevent stomach upset. Take Martidine 2.5 Tablet 10's as prescribed. You are advised to take Martidine 2.5 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not discontinue Martidine 2.5 Tablet 10's on your own. Do not take Martidine 2.5 Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Martidine 2.5 Tablet 10's may cause drowsiness and dizziness, do not drive unless you are alert. Martidine 2.5 Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Martidine 2.5 Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health condition and rule out any side effects.

Uses of Martidine 2.5 Tablet 10's

Treatment of Parkinsons disease

Medicinal Benefits

Martidine 2.5 Tablet 10's belongs to a group of medicines called anti-spasmodic agents. Martidine 2.5 Tablet 10's is used to treat the symptoms of Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders). Martidine 2.5 Tablet 10's exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Martidine 2.5 Tablet 10's improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Martidine 2.5 Tablet 10's is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Martidine 2.5 Tablet 10's is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Directions for Use

You can take Martidine 2.5 Tablet 10's with or without food. Take Martidine 2.5 Tablet 10's with food if you experience stomach upset. Based on your medical condition, your doctor will decide how long you need to take Martidine 2.5 Tablet 10's. Swallow Martidine 2.5 Tablet 10's as a whole with a glass of water; do not chew or crush the tablet.

Side Effects of Martidine 2.5 Tablet 10's

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

Drug Warnings

Do not take Martidine 2.5 Tablet 10's if you are allergic to any of its contents or have narrow-angled glaucoma. Do not discontinue Martidine 2.5 Tablet 10's on your own. Inform your doctor before taking Martidine 2.5 Tablet 10's if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Do not take Martidine 2.5 Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Martidine 2.5 Tablet 10's may cause drowsiness and dizziness, do not drive unless you are alert. Martidine 2.5 Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Martidine 2.5 Tablet 10's as it could lead to increased drowsiness and dizziness. Take special care with your dental hygiene while using Martidine 2.5 Tablet 10's (like brushing and flossing), and have regular dental check-ups.

Drug Interactions

Drug-Drug interactions: Martidine 2.5 Tablet 10's may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food interactions: Avoid consuming alcohol with Martidine 2.5 Tablet 10's as it might increase dizziness, and drowsiness.

Drug-Disease interactions: Martidine 2.5 Tablet 10's may have interactions with disease conditions such as arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, and fever.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • RASAGILINE
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Martidine 2.5 Tablet 10's can cause decreased sweating, which results in a rise in body temperature (hyperthermia). This serious side effect is greater in hot weather, so it is advisable to drink plenty of water fluids, especially in summer. However, kidney patients should consult a doctor before drinking any fluid.
  • Regular monitoring of hypotension, kidney, liver and cardiac disorder is required while taking Martidine 2.5 Tablet 10's.

Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally-occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremor, slow movements, stiffness of arms, legs, trunk, and balance problems. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Martidine 2.5 Tablet 10's as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Martidine 2.5 Tablet 10's belongs to pregnancy category C. Please consult your doctor before taking Martidine 2.5 Tablet 10's if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Martidine 2.5 Tablet 10's passes into breastmilk. Consult your doctor before taking Martidine 2.5 Tablet 10's if you are breastfeeding.

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Driving

Unsafe

Martidine 2.5 Tablet 10's may cause dizziness, drowsiness and blurred vision. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Unsafe

Martidine 2.5 Tablet 10's is not recommended for children, as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

shop no 3 matru kripa co ophsg soc ltd pooja nagar mira road (e) dist thane mh 401107 india
Other Info - MAR0321

Author Details

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FAQs

Martidine 2.5 Tablet 10's is used to treat Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders).
Martidine 2.5 Tablet 10's works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces stiffness, thereby helping the muscles move naturally.
Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Martidine 2.5 Tablet 10's may cause hallucinations if taken for a prolonged time. So, if you experience hallucinations while taking Martidine 2.5 Tablet 10's, please talk to your doctor immediately.
Antidepressants should be avoided while taking Martidine 2.5 Tablet 10's as it might increase sedative effects. Consult your doctor before taking Martidine 2.5 Tablet 10's if you are using depressants.
Dry mouth could be a side-effect of Martidine 2.5 Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent mouth drying.
Martidine 2.5 Tablet 10's should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.
Constipation may occur as a side-effect of Martidine 2.5 Tablet 10's. Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.
Consult your doctor before taking Martidine 2.5 Tablet 10's if you have glaucoma. Martidine 2.5 Tablet 10's is contraindicated in patients with narrow-angle glaucoma. Martidine 2.5 Tablet 10's may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.
No, even if you are feeling well, you shouldn't stop using Martidine 2.5 Tablet 10's suddenly because it could make your symptoms worse. Consult your physician if you have any discomfort while undergoing treatment.
The dose of Martidine 2.5 Tablet 10's varies from person to person. Consult your doctor while taking Martidine 2.5 Tablet 10's.
Yes, you can use Martidine 2.5 Tablet 10's for excessive salivation which is a symptom of Parkinson’s disease. However, it should be taken only if it is prescribed by your doctor.
Martidine 2.5 Tablet 10's has the potential to be abused, which could lead to addiction. Please consult your doctor before taking the Martidine 2.5 Tablet 10's.
As the Martidine 2.5 Tablet 10's has common side effects like dizziness, blurred vision, feeling confused, nervousness avoid driving or operating machines and also avoid taking alcohol as it increase drowsiness. Martidine 2.5 Tablet 10's may affect your body’s ability to regulate its temperature. Therefore, your body temperature may increase more than normal. So, you should also avoid areas with high temperature and high humidity.
Martidine 2.5 Tablet 10's should not be taken by patients who are allergic to any of the other substances in this medication. Patients who have a blockage in their intestines (gut) and glaucoma (increased eye pressure) should not take this medication. Also, it should be avoided by individuals who are having trouble passing urine or who are unable to do so and are not already receiving therapy for this condition. If you have any other concerns, please discuss with your doctor.
Martidine 2.5 Tablet 10's overdose may cause symptoms such as warm/dry skin, flushed face, fever, anxiety, confusion, fast/irregular heartbeat, large pupils, hallucinations, agitation, seizures, loss of consciousness, and hyperactivity. If you experience these symptoms or suspect you have taken an overdose, seek medical attention immediately.
Martidine 2.5 Tablet 10's may start working after 1 hour of taking it. However, it may take some time to show full effects. If you do not see improvement in your condition, please consult your doctor.
No, do not stop taking Martidine 2.5 Tablet 10's without first consulting your doctor. Complete the full course of treatment even if you feel better as discontinuing suddenly may cause recurring symptoms or worsen your condition.

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