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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Maitrifen Tablet is used to relieve pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Also, it lowers the elevated body temperature and mild pain. In some cases, it may cause side effects such as nausea, indigestion, stomach pain and restlessness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

Not Returnable

About Maitrifen Tablet

Maitrifen Tablet is used to relieve pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or other organs. Chronic pain lasts for a long duration and is caused by pathologies like nerve damage, osteoarthritis, etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction, or injury.

Maitrifen Tablet is composed of three medicines: Ibuprofen, Paracetamol and Caffeine. Together, they relieve symptoms of arthritis and dysmenorrhea (painful periods or menstrual cramps) and reduce fever. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Caffeine acts as a common stimulant, added to speed up the action of ibuprofen and paracetamol in relieving pain and reducing inflammation. Together all these three medicines help in reducing mild to moderate pain in a shorter duration.

Maitrifen Tablet can be taken with or after the meal. If stomach upset or irritation occurs, it is advisable to take Maitrifen Tablet with food or milk. It should be swallowed whole with a glass of water. Do not crush or chew the tablets. Do not take Maitrifen Tablet if your pain lasts for more than ten days or if the fever lasts for more than three days. Do not take a double dose if you missed one dose. Like all medicines, Maitrifen Tablet may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity.

Do not take Maitrifen Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease, or gastric ulcers/bleeding problems. Maitrifen Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause increased side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation, and fever do not disappear even after ten days.

Uses of Maitrifen Tablet

Treatment of Headache, Migraine, Muscle aches, Arthritis, Backache, Dental pain, Cold and Fever.

Directions for Use

Take it with food or milk to avoid upsetting of the stomach. Do not chew, crush or break the tablet.

Medicinal Benefits

Maitrifen Tablet is composed of ibuprofen, caffeine and paracetamol primarily used to treat mild to moderate pain. Maitrifen Tablet is prescribed mainly to treat pain and get relief from discomfort caused by conditions like tooth pain, arthritis, period pain, and other types of short-term pains. It helps in treating pain by blocking the chemical messenger in the brain responsible for causing pain. Ibuprofen works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of prostaglandin by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat, and caffeine helps in reduce drowsiness caused by paracetamol. Paracetamol has the advantage of producing less gastric irritation compared to other painkillers like aspirin.

How Maitrifen Tablet Works

Maitrifen Tablet is composed of three medicines: Ibuprofen, Paracetamol and Caffeine. Together, they relieve symptoms of arthritis and dysmenorrhea (painful periods or menstrual cramps) and reduce fever. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Caffeine acts as a common stimulant, added to speed up the action of ibuprofen and paracetamol in relieving pain and reducing inflammation. Together all these three medicines help in reducing mild to moderate pain in a shorter duration.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Maitrifen Tablet

  • Nausea
  • Indigestion
  • Stomach pain
  • Restlessness

What if I have taken an overdose of Maitrifen Tablet

Do not take more than the prescribed dose of Maitrifen Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Maitrifen Tablet should be taken with caution if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent bypass heart surgery, heart disease, or a history of allergy to any painkillers or analgesics. Caffeine can pass in the breast milk which may have a stimulating effect on the breastfed child. Therefore, Maitrifen Tablet should be avoided in pregnant or breastfeeding females.

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
How does the drug interact with Maitrifen Tablet:
Taking Ketorolac and Maitrifen Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Maitrifen Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Maitrifen Tablet:
Combining Meloxicam and Maitrifen Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Maitrifen Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
CaffeineLinezolid
Critical
How does the drug interact with Maitrifen Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Maitrifen Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Maitrifen Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Maitrifen Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Maitrifen Tablet:
Coadministration of tranylcypromine with Maitrifen Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Maitrifen Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Maitrifen Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Maitrifen Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
IbuprofenFlurbiprofen
Severe
How does the drug interact with Maitrifen Tablet:
The combined use of Flurbiprofen and Maitrifen Tablet can increase the risk of side effects in the gastrointestinal tract.

How to manage the interaction:
Taking Flurbiprofen and Maitrifen Tablet together can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPralatrexate
Severe
How does the drug interact with Maitrifen Tablet:
The combined use of Pralatrexate and Maitrifen Tablet can increase the risk of blood levels and side effects of Pralatrexate.

How to manage the interaction:
Co-administration of Pralatrexate and Maitrifen Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like mouth ulcers or sores, vomiting, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, paleness, dizziness or fainting, unusual bruising or bleeding, infection, and flu-like symptoms (fever, chills, body aches, sore throat, muscle weakness), consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenFondaparinux
Severe
How does the drug interact with Maitrifen Tablet:
Coadministration of fondaparinux with Maitrifen Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Fondaparinux and Maitrifen Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
IbuprofenLithium
Severe
How does the drug interact with Maitrifen Tablet:
Coadministration of Lithium and Maitrifen Tablet can increases the blood levels of Lithium.

How to manage the interaction:
Co-administration of Lithium and Maitrifen Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like drowsiness, dizziness, confusion, diarrhea, vomiting, muscle weakness, muscle inco-ordination, tremor, blurred vision, ringing in the ear, excessive thirst, and increased urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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IBUPROFEN-400MG+PARACETAMOL-325MG+CAFFEINE-30MGFruit juices, Fruits
Mild

Drug-Food Interactions

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IBUPROFEN-400MG+PARACETAMOL-325MG+CAFFEINE-30MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grape juice increases the effect of caffeine. Limit your consumption of grapefruit and grapefruit juice during treatment with caffeine.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, calcium enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue. 
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights. 
  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long term immobility is harmful in conditions like arthritis. Use back support like a rolled up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a foot rest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Maitrifen Tablet Substitute

Substitutes safety advice
  • Flexon Plus Tablet

    1.40per tablet
  • Norflam Plus Tablet

    1.13per tablet
  • Achrid 400 mg/325 mg/30 mg Tablet

    0.74per tablet
  • Biomol Plus 400mg/325mg/30mg Tablet

    1.62per tablet
  • Ediflam Plus Tablet

    1.13per tablet
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Alcohol

Caution

Taking Maitrifen Tablet with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Maitrifen Tablet.

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Pregnancy

Unsafe

Use of Maitrifen Tablet during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Unsafe

Caffeine can pass in the breast milk which may have stimulating effect on breastfed child. Therefore, Maitrifen Tablet should be avoided in the breastfeeding stage.

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Driving

Caution

After taking Maitrifen Tablet you may notice dizziness, sleepiness, drowsiness or fatigue as it contain caffeine as stimulant. So, in this you should stop taking Maitrifen Tablet and contact your doctor.

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Liver

Caution

Maitrifen Tablet to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Maitrifen Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Maitrifen Tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

FAQs

Maitrifen Tablet is used to relieve pain in conditions like headache, migraine, muscle aches, arthritis, backache, dental pain, cold and fever.
No, Maitrifen Tablet should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Maitrifen Tablet, take it in doses and duration mentioned by your doctor.
No, it is not advisable to take Maitrifen Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Maitrifen Tablet.
Yes, Maitrifen Tablet is a short term medication and if you feel better you can stop taking Maitrifen Tablet, but only after consulting your doctor.
Maitrifen Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.
No, Maitrifen Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take Maitrifen Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.
It depends on whether your cough and cold pills contain ibuprofen, paracetamol and caffeine or not. If it contains these three medicines, do not take it. It may lead to over dosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.
Do not give Maitrifen Tablet to children under 6 years old or children weighing less than 20 kg (44 lbs). This medication can cause kidney problems in children and teenagers who are dehydrated. Be cautious and consult your doctor if you have any questions or concerns.
Caffeine acts as a stimulant. It is added to speed up the action of ibuprofen and paracetamol in relieving pain and reducing inflammation.
Taking too much caffeine can lead to negative side effects like drowsiness, dizziness, and sleepiness. Therefore, limit intake of other caffeine-containing foods and drinks, such as coffee, tea, chocolate, and fizzy drinks (like energy drinks or soda).
Stop taking Maitrifen Tablet and consult or call your doctor immediately if you have a hypersensitive or allergic reaction after taking Maitrifen Tablet.
No, it is not specifically intended to treat viral infections. Maitrifen Tablet is intended to relieve pain and inflammation associated with headaches, migraine, muscle aches, arthritis, backache, and dental pain.
No, it is not an antibiotic. Maitrifen Tablet is a combination medication containing caffeine (a stimulant), ibuprofen (an analgesic), and paracetamol (a mild analgesic and antipyretic).
Consult the doctor before taking Maitrifen Tablet if you have high blood pressure. The doctor will decide if it is safe for you or not.
Taking steroids with Maitrifen Tablet may increase the risk of stomach ulcers and bleeding. Therefore, steroids should be used with Maitrifen Tablet cautiously and only if advised by the doctor.
Maitrifen Tablet is not recommended for use in patients with severe kidney problems. Consult the doctor before taking Maitrifen Tablet if you have kidney problems.
Maitrifen Tablet is a combination medication, it contains caffeine (a stimulant), ibuprofen (an analgesic), and paracetamol (a mild analgesic and antipyretic). It is used in the treatment of headaches, migraine, muscle aches, arthritis, backache, dental pain, colds, and fever.
Maitrifen Tablet may cause nausea and vomiting in some individuals as a side effect. Eat small, frequent meals, drink water regularly and avoid spicy foods if you have nausea/vomiting. If nausea/vomiting persists or worsens, consult your doctor.
Maitrifen Tablet may cause dizziness in some individuals. Do not drive or operate machinery if you experience dizziness.
Maitrifen Tablet contains caffeine which may cause insomnia in some individuals. Consult the doctor if you have problems with sleep during treatment with Maitrifen Tablet.
Taking Maitrifen Tablet for a long time or in high doses may hurt your kidneys. Ibuprofen and paracetamol can reduce blood flow to the kidneys and cause damage, while caffeine can increase urine production, putting extra strain on the kidneys. To stay safe, always follow the doctor’s instructions.
No, taking Maitrifen Tablet in higher doses will not make it more effective and may even be harmful. Taking more than the recommended dose can increase the risk of side effects, such as stomach ulcers, bleeding, and kidney damage. Always follow the recommended dosage and duration of use. If you're not getting relief from your symptoms, consult your doctor for alternative treatments or adjustments to your dosage.
Maitrifen Tablet should be stored in a cool and dry place away from sunlight. Keep it away from children’s reach.
It is specifically not a pain killer. Maitrifen Tablet is a combination medication. However, it is used to relieve pain.
Maitrifen Tablet is safe for the kidney when used as prescribed by your doctor. However, it may damage your kidney if used in higher doses or for a longer duration. Hence, take it only as advised by the doctor.
Maitrifen Tablet is used to relieve pain and may not help with cold. Consult the doctor if you have a cold; the doctor will prescribe suitable medication.
No, Maitrifen Tablet should be taken with food to avoid stomach upset. Consult your doctor if you have any concerns.
Maitrifen Tablet may generally start to show its effect within 30 minutes to 1 hour after consumption. However, the exact timing can vary depending on individual factors. Please consult your doctor if you have any concerns regarding it.
It is safe to take Maitrifen Tablet daily for the duration prescribed by the doctor, generally up to 5 to 7 days. However, it is important to follow the recommended dosage and consult your doctor if you need to take it for a longer period.
The common side effects of Maitrifen Tablet include nausea, indigestion, stomach pain, and restlessness. Most of these side effects resolve gradually over time. However, if it persists or worsens please consult your doctor.

Country of origin

India
Other Info - MA65183

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