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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Magxel 1000 mg Injection 2 ml is used to treat, prevent, and control seizures (fits) in preeclampsia and eclampsia (severe complications in pregnancy that occur due to high blood pressure). It contains Magnesium sulfate. It is a mineral supplement and an electrolyte. It is also an anticonvulsant that prevents and controls seizures (fits) in preeclampsia and eclampsia. It is also used to treat abnormally low magnesium levels in the blood. It works by blocking neuromuscular transmission. It further has a depressant effect on the central nervous system. Magnesium sulfate aids in the normal functioning of cells, nerves, muscles, bones, and the heart.
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Manufacturer/Marketer

Questus Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Magxel 1000 mg Injection 2 ml

Magxel 1000 mg Injection 2 ml is a mineral supplement, and an anticonvulsant primarily used to prevent and control seizures (fits) in preeclampsia and eclampsia (serious complications in pregnancy that occur due to high blood pressure). Magxel 1000 mg Injection 2 ml is also used to treat hypomagnesaemia, a condition characterized by abnormally low magnesium levels in the blood.

Magxel 1000 mg Injection 2 ml contains Magnesium sulfate. It is a mineral supplement and an electrolyte. It prevents and controls seizures by blocking neuromuscular transmission, the transfer of nerve impulses to the heart. It further has a depressant effect on the central nervous system and acts peripherally to cause vasodilation.

Magxel 1000 mg Injection 2 ml will be administered by a healthcare professional. It causes some side effects, although not everybody gets them. Side effects include dizziness, drowsiness, low blood pressure, flushing, and sweating. Most of these effects do not require medical attention and will resolve gradually over time. However, if any of these side effects persist or worsen, please seek medical advice.

Before receiving Magxel 1000 mg Injection 2 ml, let your doctor know if you have kidney/liver/heart diseases, dehydration, stomach/gastrointestinal disorders, myasthenia gravis (muscle weakness) and sensitivities. Inform your doctor if you are a pregnant and breastfeeding woman before taking Magxel 1000 mg Injection 2 ml. The safety and efficacy of this medicine have not been established in children younger than twelve years of age.

Uses of Magxel 1000 mg Injection 2 ml

Treatment of Seizures (fits) in preeclampsia, eclampsia, and hypomagnesaemia

Medicinal Benefits

Magxel 1000 mg Injection 2 ml contains Magnesium sulfate. It is a mineral supplement and an electrolyte. It is also an anticonvulsant that prevents and controls seizures (fits) in preeclampsia and eclampsia. Magxel 1000 mg Injection 2 ml is also used to treat abnormally low magnesium levels in the blood. It works by blocking neuromuscular transmission. It further has a depressant effect on the central nervous system. Magnesium sulfate aids in the normal functioning of cells, nerves, muscles, bones, and the heart.

Directions for Use

A healthcare professional will administer it. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Magxel 1000 mg Injection 2 ml

  • Dizziness
  • Drowsiness 
  • Low blood pressure
  • Flushing
  • Sweating

Drug Warnings

Please inform your doctor about all the prescription and over-the-counter medicines you take before starting Magxel 1000 mg Injection 2 ml. Inform your doctor if you have a medical history of kidney/liver/heart diseases, dehydration, stomach/gastrointestinal disorders, alcohol dependence, and myasthenia gravis (muscle weakness) before starting Magxel 1000 mg Injection 2 ml. Let your doctor know if you are a pregnant or breastfeeding woman before taking Magxel 1000 mg Injection 2 ml. Avoid alcohol consumption while undergoing treatment with Magxel 1000 mg Injection 2 ml as it might interact and increase the occurrence of side effects. Magxel 1000 mg Injection 2 ml can cause dizziness and drowsiness affecting your ability to drive; hence drive only when you are alert and focused. Magxel 1000 mg Injection 2 ml is not recommended in children younger than 12 years of age.

Drug Interactions

Drug-Drug Interactions: Magxel 1000 mg Injection 2 ml may interact with blood pressure medicines (nifedipine, nimodipine), heart-related medicines (digitalis), immunosuppressants (cyclosporine), antifungals (amphotericin B), muscle relaxants (tubocurarine), chemotherapy drugs (cisplatin) aminoglycoside antibiotics, and water pills.

Drug-Food Interactions: Avoid the intake of alcohol and caffeinated drinks while using Magxel 1000 mg Injection 2 ml to prevent any interactions.

Drug-Disease Interactions: Inform your doctor about myasthenia gravis, liver/kidney/heart diseases, alcohol dependence, dehydration, and stomach/gastrointestinal disorders. Magnesium sulfate is not recommended for use in severely impaired renal function. It should not be used in a hepatic coma if there is a risk of renal failure.

Drug-Drug Interactions Checker List

  • NIFEDIPINE
  • NIMODIPINE
  • DIGITALIS
  • CYCLOSPORINE
  • AMPHOTERICIN B
  • TUBOCURARINE
  • CISPLATIN

Habit Forming

No

Diet & Lifestyle Advise

  • Meditation, walking, involving in a task, and smelling a strong odour are a few self-control methods to prevent seizures.
  • Rest properly, and avoid stress by doing meditation or yoga.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Include Vitamin D-rich foods like fatty fish, mackerel, tuna, dairy products, orange juice, soy milk, cereals, beef liver, cheese, and egg yolks in your diet.
  • Also, it is advised to take folic acid and vitamin K-rich foods and supplements during pregnancy.

Special Advise

  • Your doctor may advise you to get regular blood tests to test the amount of magnesium in your blood.
  • Monitor your blood pressure and sugar levels regularly while using Magxel 1000 mg Injection 2 ml.
  • Your blood calcium levels need to be regularly monitored whilst taking Magnesium sulfate injection.

Disease/Condition Glossary

Pre-eclampsia: It is a pregnancy complication caused in pregnancy due to high blood pressure. Symptoms include protein in the urine, swelling of the hands and face, shortness of breath, and abdominal pain. 

Eclampsia: It is a complication that is characterized by convulsions/seizures during a woman's pregnancy or shortly after giving birth. Symptoms include upper-right abdominal pain, severe headache and vision and mental status changes.

Fits/Seizure: It is characterized as a sudden and uncontrollable electrical disturbance in the brain. Symptoms include uncontrolled jerking movements of the arms and legs, loss of consciousness, and temporary confusion.

Hypomagnesaemia: It is a condition that occurs when a person has abnormally low levels of magnesium. This occurs when a person does not get enough magnesium in their diet, or he/she is unable to absorb magnesium properly. Symptoms include nausea, vomiting, weakness, personality changes, tremor, fatigue, seizures, irregular heartbeat, and high blood pressure.

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Alcohol

Caution

Avoid taking alcohol while using Magxel 1000 mg Injection 2 ml since it may interact and worsen the side effects. Please seek medical advice for more information.

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Pregnancy

Caution

Magxel 1000 mg Injection 2 ml is a pregnancy category D drug and has shown harmful effects on the foetus. However, seizure control is mandatory during eclampsia in pregnancy. Inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Magxel 1000 mg Injection 2 ml if the benefits outweigh the risks.

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Breast Feeding

Caution

Magnesium sulfate passes into breast milk. If you are breastfeeding, please inform your doctor before receiving Magxel 1000 mg Injection 2 ml.

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Driving

Caution

You may experience dizziness and drowsiness while using Magxel 1000 mg Injection 2 ml. In such cases, do not drive or operate machinery until you are mentally alert and focused.

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Liver

Caution

Magxel 1000 mg Injection 2 ml should be used with caution in patients with liver problems. Please inform your doctor if you have a liver impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Magxel 1000 mg Injection 2 ml should be used with caution in patients with kidney problems. Please inform your doctor if you have kidney impairment. Your doctor may adjust your dose depending on your current medical conditions.

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Children

Unsafe

Magxel 1000 mg Injection 2 ml is not recommended in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

No 3-3, 40, E Marredpally, Mamidpalli, Malkajgiri, Secunderabad, Telangana 500026
Other Info - MAG0566

Author Details

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FAQs

Magxel 1000 mg Injection 2 ml is used to treat Seizures (fits) in preeclampsia, eclampsia, and hypomagnesaemia.
Magxel 1000 mg Injection 2 ml contains Magnesium sulfate. It works by treating low levels of magnesium in the body in hypomagnesaemia. It also prevents and controls seizures that occur due to high blood pressure in pregnancy. It works by blocking the nerve impulses to the heart muscles.
If you drink alcohol or caffeine drinks, smoke, or use any street drugs regularly, please inform your doctor before starting Magxel 1000 mg Injection 2 ml. These products may affect the working of Magxel 1000 mg Injection 2 ml.
Inform your doctor if you have kidney/liver/heart diseases, dehydration, stomach/gastrointestinal disorders, and myasthenia gravis (muscle weakness) before using Magxel 1000 mg Injection 2 ml. Magnesium sulfate is not recommended for use in severely impaired renal function. It should not be used in a hepatic coma if there is a risk of renal failure.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.
Magxel 1000 mg Injection 2 ml contains magnesium sulphate, which prevents and treats low magnesium levels in your body (hypomagnesaemia).

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