Maczo 90mg/100mg/48mg Tablet is a combination medication that belongs to a class of drugs called 'analgesic' used to relieve musculoskeletal pain in the conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It may also provide relief from acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache. Pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time (acute) or long time (chronic).  

Maczo 90mg/100mg/48mg Tablet contains Rutoside, Trypsin-chymotrypsin and Bromelain. Trypsin-chymotrypsin and Bromelain are enzymes that have antiseptic and anti-inflammatory properties. They reduce pain, swelling, and inflammation by increasing the blood supply to the affected area. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralizing the chemicals (free radicals) that cause cell damage. 

Take Maczo 90mg/100mg/48mg Tablet with or without food as prescribed by your doctor and swallow it whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on the duration based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhoea, rash, or mouth sores. Most of these side effects of Maczo 90mg/100mg/48mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Maczo 90mg/100mg/48mg Tablet or any other medicines, please tell your doctor. Avoid Maczo 90mg/100mg/48mg Tablet in patients who are allergic to pineapple, carrot, papaya, fennel, and pollens. Maczo 90mg/100mg/48mg Tablet is not recommended for pregnant women as it contains Bromelain, which may cause abortion or miscarriage. If you are pregnant or planning for pregnancy, please consult a doctor before taking Maczo 90mg/100mg/48mg Tablet. Before undergoing any planned surgery, inform your doctor that you are taking Maczo 90mg/100mg/48mg Tablet. 

Maczo 90mg/100mg/48mg Tablet contains Rutoside, Trypsin-chymotrypsin and Bromelain. Trypsin-chymotrypsin and Bromelain are enzymes that have antiseptic and anti-inflammatory properties. They reduce pain, swelling, and inflammation by increasing the blood supply to the affected area. Rutoside is an antioxidant and anti-inflammatory agent. It prevents further swelling and inflammation by neutralising the chemicals (free radicals) that cause cell damage. Thereby, Maczo 90mg/100mg/48mg Tablet helps relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.  

• Vomiting
• Nausea
• Diarrhoea
• Rash
• Mouth sores
• Gastrointestinal discomfort

If you are allergic to Maczo 90mg/100mg/48mg Tablet or any other medicines, please tell your doctor. People allergic to pineapple, carrot, papain, fennel, and pollen should avoid the intake of Maczo 90mg/100mg/48mg Tablet. Maczo 90mg/100mg/48mg Tablet is not recommended for pregnant women as it contains Bromelain, which may cause miscarriage, so if you are pregnant or planning for pregnancy, let your doctor know about this. If you are about to undergo any surgery, inform your doctor that you are taking Maczo 90mg/100mg/48mg Tablet. It should be stopped a minimum of 2 weeks before surgery as Maczo 90mg/100mg/48mg Tablet may increase the risk of bleeding during and after surgery. If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Maczo 90mg/100mg/48mg Tablet.

Drug-Drug Interaction: Maczo 90mg/100mg/48mg Tablet may have interaction with pain killers (aspirin, diclofenac, ibuprofen, naproxen), blood thinners (warfarin, clopidogrel, dalteparin, enoxaparin, heparin), antibiotics (amoxicillin, demeclocycline, minocycline, tetracycline), drugs used to dissolve blood clots (alteplase, reteplase, streptokinase), high blood pressure-lowering medicines (captopril, enalapril, fosinopril, lisinopril).

Drug-Food Interaction: Maczo 90mg/100mg/48mg Tablet may interact with ginger, garlic, asafoetida, alfalfa, arnica, fenugreek, potato, soybean, liquorice, red clover, celery, angelica, meadowsweet, quassia, willow, chestnut, chamomile, and clover.

Drug-Disease Interaction: If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), or kidney or liver disorders, inform your doctor before taking Maczo 90mg/100mg/48mg Tablet.

• ASPIRIN
• DICLOFENAC
• IBUPROFEN
• NAPROXEN
• WARFARIN
• CLOPIDOGREL
• DALTEPARIN
• ENOXAPARIN
• HEPARIN
• AMOXICILLIN
• DEMECLOCYCLINE
• MINOCYCLINE
• TETRACYCLINE
• ALTEPLASE
• RETEPLASE
• STREPTOKINASE
• CAPTOPRIL
• ENALAPRIL
• FOSINOPRIL
• LISINOPRIL

• Turmeric and fish oils can help in reducing inflammation in the tissue.
• Do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also increase your muscle strength by lifting light weights.
• Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
• In chronic arthritis or joint pain, fish like salmon, trout, tuna, and sardines are included. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which may increase inflammation.
• Your sitting posture is essential, especially when you have pain and inflammation conditions. Try to sit as little as possible and only briefly (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your hips and knees at a right angle. Besides this, you can use a footrest if required.

Patients with severe inborn bleeding disorders like haemophilia, severe liver damage, and dialysed patients must not use Maczo 90mg/100mg/48mg Tablet. 

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. It can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or organs. While chronic pain lasts lifelong and can occur due to severe inflammation or tissue damage, such as osteoarthritis and rheumatoid arthritis. 

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.