MACROMYCIN TABLET belongs to a group of medicines known as macrolide antibiotics primarily used to treat cryptosporidiosis (a diarrheal disease caused by microscopic parasites, cryptosporidium), susceptible infections, and soft tissue infections. It is also used to treat a parasitic infection known as toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child. A bacterial infection is a condition in which bacteria grows in the body and causes infection. It can target any body part and multiple very quickly. Toxoplasmosis infection can cause complications such as miscarriage, stillbirth, and damage to a baby’s brain and other organs, particularly the eyes, at birth or early childhood, or even as adults with a weak immune system.

MACROMYCIN TABLET contains ‘Spiramycin,’ an antibiotic that treats bacterial infections of the abdomen, bone, skin, heart, and soft tissues. It may also be used to reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. MACROMYCIN TABLET works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial and parasitic reproduction but doesn't kill them. 

Take MACROMYCIN TABLET as prescribed by your doctor. You are advised to take MACROMYCIN TABLET for the duration as prescribed, depending on your medical condition. MACROMYCIN TABLET causes side effects in some people. Common side effects of MACROMYCIN TABLET include stomach pain, nausea, vomiting, and diarrhea. Most of these side effects of MACROMYCIN TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to MACROMYCIN TABLET or any other medicines, please tell your doctor. Do not use MACROMYCIN TABLET while having vaccinations with live bacterial vaccines (typhoid vaccine) since MACROMYCIN TABLET may affect the vaccine's activity. MACROMYCIN TABLET should be used only with a doctor's advice during pregnancy and breastfeeding. Do not give this medicine to your child without medical advice. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare genetic blood disorder), or electrolyte imbalance (low potassium or magnesium level).

MACROMYCIN TABLET contains ‘Spiramycin’ as an antibiotic that treats bacterial infections like various infections of the abdomen, bone, skin, heart and soft tissues. It may also reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. MACROMYCIN TABLET works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. MACROMYCIN TABLET effectively treats infections caused by gram-positive and aerobic (living with air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumonia, N. gonorrhoea,  gram-negative bacteria, and cryptosporidium spices. MACROMYCIN TABLET treats serious infections caused by susceptible aerobic bacteria in the abdomen, gastrointestinal tract, lower respiratory tract, skin, and in genitourinary area. It will not work for viral infections (such as the common cold or flu).

• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Allergy
• Abnormal liver function
• Abnormal heart rate
• Hypotension

Do not use MACROMYCIN TABLET if you are allergic to MACROMYCIN TABLET or its components. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare inherited blood disorders), or electrolyte imbalance (low potassium or magnesium level). Regular monitoring of liver function tests may be required while using MACROMYCIN TABLET. In rare cases, the use of MACROMYCIN TABLET can cause diarrhoea, so in case you have watery or bloody diarrhoea, stop taking MACROMYCIN TABLET and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you.  MACROMYCIN TABLET is safe to use during pregnancy. However, please consult your doctor if you are pregnant, planning for pregnancy, or breastfeeding before using MACROMYCIN TABLET. It should be taken by the children only if the doctor has prescribed it. In some cases, MACROMYCIN TABLET may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause fast/irregular heartbeat and other symptoms (such as severe dizziness and fainting) that need medical attention immediately. Elderly adults may be more sensitive to the side effects of MACROMYCIN TABLET, especially QT prolongation. MACROMYCIN TABLET may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to. Do not skip the doses and finish the full course of treatment even if you feel better. Stopping the MACROMYCIN TABLET too early may lead to the infection returning or worsening.

Drug-Drug Interaction: MACROMYCIN TABLET have interactions with ergot alkaloids (ergotamine, dihydroergotamine), drugs used to treat abnormal heart rhythm (amiodarone, dofetilide, pimozide, procainamide, quinidine), macrolide antibiotics (erythromycin).

Drug-Food Interaction: No relevant drug-food interaction was found with MACROMYCIN TABLET. As a precautionary measure, the consumption of alcoholic beverages should be avoided as it may lead to drowsiness and dizziness.

Drug-Disease Interaction: MACROMYCIN TABLET should not be given to people with liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), electrolyte imbalance (low potassium or magnesium level), colitis (inflammation of the intestine), and porphyria (rare genetic blood disorder).

• ERGOTAMINE
• DIHYDROERGOTAMINE
• AMIDODARONE
• DOFETILIDE
• PIMOZIDE
• PROCAINAMIDE
• QUINIDINE
• ERYTHROMYCIN

• Probiotics should be taken after taking a full course of MACROMYCIN TABLET in order to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine. 

• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

• Avoid taking too much calcium, iron-enriched foods, and drinks as it might affect the working of MACROMYCIN TABLET. 

• Avoid intake of alcoholic beverages with MACROMYCIN TABLET as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the MACROMYCIN TABLET in fighting off infections.

• Liver function monitoring (liver function tests) is recommended in patients with severe liver disease.

• MACROMYCIN TABLET may cause Clostridium difficile-associated diarrhea (CDAD); hence it is advised to undergo regular gastrointestinal screening.

A bacterial infection:  It is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

Toxoplasmosis: is an infection caused by parasites toxoplasma gondii found in contaminated food and cat feces. It can cause serious complications for pregnant women, such as miscarriage, stillbirths, and damage to the baby’s brain and other organs, particularly the eyes, at birth or early childhood, and people with weakened immune systems. Symptoms include muscle pain, fever, headache, etc.