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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:08 PM IST
Macphylline Capsule is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It contains Acebrophylline, which works by relaxing muscles and widening the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, it helps to cough out easily and makes breathing easier by opening airways. Some people may experience diarrhoea, nausea, vomiting, dizziness, heartburn, stomach discomfort, skin rash or drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Macphylline Capsule

Macphylline Capsule is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Macphylline Capsule contains Acebrophylline, which works by relaxing muscles and widening the airways of the lungs. Additionally, Macphylline Capsule also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Therefore, it helps cough out easily and makes breathing easier by opening airways.

Take Macphylline Capsule as prescribed. Your doctor will recommend how often you take Macphylline Capsule based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, dizziness, heartburn, stomach discomfort, skin rash or drowsiness. Most of these side effects of Macphylline Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Macphylline Capsule or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning or last longer than usual, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Macphylline Capsule as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Macphylline Capsule . Do not take Macphylline Capsule if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Macphylline Capsule if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Macphylline Capsule .

Uses of Macphylline Capsule

Treatment of Asthma, Chronic obstructive pulmonary disease (COPD).

Medicinal Benefits

Macphylline Capsule is a bronchodilator and mucolytic (mucus thinner) agent that is used to treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Macphylline Capsule works by relaxing muscles and widening the airways of the lungs. Additionally, Macphylline Capsule helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Therefore, it helps cough out easily and makes breathing easier by opening airways. Macphylline Capsule helps prevent an asthma attack and allows you to exercise freely if it is taken before exercise.

Directions for Use

Tablet/Capsule: Take it with food to avoid stomach upset or as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Syrup: Shake the bottle well before use. Check the label for directions and take it in doses as prescribed by your doctor with the help of a measuring cup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Macphylline Capsule

  • Diarrhoea

  • Nausea

  • Vomiting

  • Dizziness

  • Heartburn

  • Stomach discomfort

  • Skin rash

  • Drowsiness

Drug Warnings

If you are allergic to Macphylline Capsule or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning or lasts longer than usual, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Macphylline Capsule as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Macphylline Capsule . Do not take Macphylline Capsule if you have heart rhythm disorder that causes fast heartbeats. Avoid taking Macphylline Capsule if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Macphylline Capsule .

Drug Interactions

Drug-Drug Interaction: Macphylline Capsule may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline), anthelmintic (thiabendazole),  corticosteroids (prednisone) and oral contraceptives (ethinylestradiol). 

Drug-Food Interaction: Macphylline Capsule may interact with alcohol. Therefore, avoid intake of alcohol with Macphylline Capsule as it may increase drowsiness. Also, avoid or limit the intake of caffeine with Macphylline Capsule as it may cause side effects.

Drug-Disease Interaction: Avoid taking Macphylline Capsule if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Macphylline Capsule

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AMOXICILLIN
  • DILTIAZEM
  • VERAPAMIL
  • ISOPRENALINE
  • DOXYCYCLINE
  • PREDNISONE
  • ETHINYLESTRADIOL
  • THIABENDAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.

  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.

  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen asthma symptoms.

  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.

  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

  • Quit smoking as it may reduce the effectiveness of the Macphylline Capsule and irritate the lungs worsening breathing problem.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Unsafe

Avoid consumption of alcohol with Macphylline Capsule as it may increase drowsiness. Please consult a doctor before consuming alcohol with Macphylline Capsule .

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Pregnancy

Unsafe

Macphylline Capsule is not recommended for pregnant women. Please consult a doctor before using Macphylline Capsule if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Macphylline Capsule is excreted in human milk. Please consult a doctor before taking Macphylline Capsule if you are breastfeeding.

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Driving

Safe

Macphylline Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Macphylline Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Macphylline Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Macphylline Capsule should be used with caution in children in doses as prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0095

Author Details

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FAQs

Macphylline Capsule is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing muscles and widening the airways of the lungs.
Macphylline Capsule should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Macphylline Capsule so that the dose may be adjusted or an alternate medicine may be prescribed.
No, you are not recommended to take erythromycin with Macphylline Capsule as co-administration of these medicines may increase the risk of adverse effects of Macphylline Capsule . However, please consult a doctor before using other medicines with Macphylline Capsule .
You are recommended to avoid taking Macphylline Capsule if you are allergic to acebrophylline, ambroxol, theophylline or suffering from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders or had heart attack. However, inform your doctor if you have any of these conditions before taking Macphylline Capsule .
No, you are not recommended to smoke while taking Macphylline Capsule as it may reduce the effectiveness of Macphylline Capsule .
No, you are not recommended to stop taking Macphylline Capsule without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Macphylline Capsule for as long as your doctor has prescribed it and if you experience any difficulty while taking Macphylline Capsule , please consult your doctor.
No, Macphylline Capsule does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
No, Macphylline Capsule is not a steroid. Macphylline Capsule is a bronchodilator and mucolytic (mucus thinner) agent.
You are recommended to take Macphylline Capsule for as long as it is prescribed by your doctor. The duration depends on the cause of illness and the underlying disease.
No. Macphylline Capsule is not an antibiotic.
Birth control pills may interfere with Macphylline Capsule clearance, increasing its levels and risk of side effects. Therefore, if you are taking birth control pills, inform your doctor as the dose of Macphylline Capsule needs to be reduced.
Macphylline Capsule should be taken exactly as advised by the doctor. Take it with food to avoid stomach upset. Swallow it as a whole with a glass of water. Do not open, crush or chew it.
If you are taking furosemide along with Macphylline Capsule , you should take caution as combined use of these medicines may decrease potassium levels. Therefore, it is necessary to regularly monitor potassium levels.
Macphylline Capsule contains Acebrophylline, which works by relaxing muscles and widening the airways of the lungs. Additionally, Macphylline Capsule also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, it helps cough out easily and makes breathing easier by opening airways.
You are recommended to avoid consuming large quantities of caffeine-containing food or drinks as it may increase the risk of side effects.
You are advised to consult your doctor before taking Macphylline Capsule if you are pregnant or breastfeeding.
Macphylline Capsule may cause side effects such as nausea, vomiting, diarrhea, heartburn, dizziness, and stomach discomfort. If these side effects persist or worsen, please consult your doctor.
Store Macphylline Capsule at room temperature. Protect from moisture. Keep it out of reach of children.

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