Macpee Tablet belongs to the class of medications called ‘Cholinergic agents’ used to treat urinary retention (holding urine in the bladder) due to surgery, childbirth, or bladder muscle problems.

Macpee Tablet contains ‘bethanechol’ that helps treat the inability to urinate by acting on the bladder muscles. It contracts the detrusor muscle (a bladder muscle) pushing the urine out of the bladder, thus starting the urination process and emptying it. 

Take Macpee Tablet as prescribed. Your doctor will advise you on how often you take Macpee Tablet based on your medical condition. You may experience some side effects such as abdominal discomfort, nausea, diarrhea, urgent desire to urinate, excessive salivation, flushing (reddening of the skin), and sweating. Consult a doctor if these side effects do not go away or worsen.

Do not take Macpee Tablet if you are allergic to ‘bethanechol’ or any other contents. Before taking Macpee Tablet , inform your doctor if you have undergone surgery, or previously been diagnosed with gastrointestinal (stomach and intestine) problems, urinary blockages, asthma, heart diseases, hyperthyroidism, seizures, Parkinson’s disease, or blood pressure problems (low or high). Also, tell your doctor if you are pregnant or breastfeeding. If Macpee Tablet is prescribed, do not take alcohol while using Macpee Tablet , as the condition may worsen due to increased risk of side effects.  It would be best if you refrained from activities that require you to stay alert such as driving or operating heavy machinery as Macpee Tablet may cause dizziness.

Macpee Tablet is a cholinergic agent used to treat urinary retention. It works by acting on the detrusor muscle (bladder muscle) to push the urine out of the bladder. The detrusor muscle contracts strong enough to start the micturition (the process of urination), thus emptying the bladder.

• Abdominal discomfort
• Nausea
• Diarrhoea
• Urgent desire to urinate
• Excessive salivation
• Flushing (reddening of the skin)
• Sweating

Do not take Macpee Tablet if you are allergic to any contents of it. Before taking Macpee Tablet , inform your doctor if you had recent surgeries, stomach or intestinal ulcers, bladder obstruction, peritonitis (infection of the stomach lining), or inflammatory bowel disease (inflammation of the digestive tract). Use of Macpee Tablet in the above illnesses may worsen the condition. Macpee Tablet may cause atrial fibrillation (heart rhythm problems) in patients with hyperthyroidism (overactive thyroid). Macpee Tablet may flare up the symptoms when used in patients with lung diseases such as asthma or chronic obstructive pulmonary disorder (COPD) as it can constrict the airways. Do not use Macpee Tablet in patients with heart diseases, hypotension (low blood pressure), bradycardia (low heart rate), seizures, and Parkinson’s disease. Do not consume alcohol as it can increase dizziness. Inform your doctor if you are pregnant or breastfeeding. To avoid dizziness from this medicine, stand up slowly from a sitting or lying position.

Drug-drug interactions: Macpee Tablet effectiveness may alter when used with other cholinergic or anticholinergic drugs and antihypertensive drugs (mecamylamine and trimethaphan).

Drug-food interactions: No interactions found.

Drug-disease interactions: Macpee Tablet should be used with caution in patients with urinary bladder obstruction, inflammatory bowel diseases (inflammation of the digestive tract), hyperthyroidism (overactive thyroid), stomach ulcers, lung problems, bradycardia (decreased heart rate), hypotension (low blood pressure), coronary artery disease (a heart disease), seizures (fits), and Parkinson’s disease (a brain disorder).

• MECAMYLAMINE
• TRIMETHAPHAN

• Drink more fluids in the morning and afternoon rather than at night.

• Limit alcohol and caffeine intake. 

• Maintain a healthy weight. Shed excess weight if you are overweight or obese. 

• Consume a healthy diet containing whole grains, fresh fruits and vegetables. 

Urinary retention: Urinary retention is the inability to empty the bladder. It occurs due to obstruction in the urinary tract or the presence of weak bladder muscles due to surgery, childbirth, or any underlying conditions.