Macox-ZH Tablet belongs to the group of medicines called 'anti-tuberculosis drugs' primarily used to treat tuberculosis, also known as TB. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine, and bone marrow. Macox-ZH Tablet does not work against infections caused by the virus, including colds and flu.

Macox-ZH Tablet combines three anti-tuberculosis drugs: Rifampicin, Isoniazid, and Pyrazinamide. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Pyrazinamide inhibits the growth of the bacteria. Together, Macox-ZH Tablet kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

Take Macox-ZH Tablet as prescribed. Sometimes, you may experience common side effects such as weakness, nausea, vomiting, stomach pain, and joint or muscle pain. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking Macox-ZH Tablet as they might cause interaction. Maintain a gap of one hour between Macox-ZH Tablet and antacid medicines. Consult your doctor before taking Macox-ZH Tablet if you are pregnant. Avoid breastfeeding while taking Macox-ZH Tablet as it passes into breast milk.

Macox-ZH Tablet combines three anti-tuberculosis drugs: Rifampicin, Isoniazid, and Pyrazinamide. Macox-ZH Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Pyrazinamide inhibits the growth of bacteria. Together, Macox-ZH Tablet kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

• Weakness
• Nausea
• Vomiting
• Stomach pain
• Joint or muscle pain

Do not take Macox-ZH Tablet if you are allergic to any of its contents, if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting Macox-ZH Tablet, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking Macox-ZH Tablet as they might cause interaction. Maintain a gap of one hour between Macox-ZH Tablet and antacid medicines. Consult your doctor before taking Macox-ZH Tablet if you are pregnant. Avoid breastfeeding while taking Macox-ZH Tablet as it passes into breast milk. Macox-ZH Tablet may cause dizziness, and vision problems, so drive cautiously. Avoid alcohol consumption while taking Macox-ZH Tablet as it could lead to increased liver damage. Keep your doctor informed about your health condition and all the medicines you take to rule out any interactions.

Drug-Drug Interactions: Macox-ZH Tablet may interact with an antibiotic (erythromycin), painkiller (acetaminophen), anti-diabetic (insulin isophane), anti-HIV (saquinavir, ritonavir), or supplement (ergocalciferol).

Drug-Food Interactions: Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking Macox-ZH Tablet as they might cause interaction.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), peripheral neuropathy (numbness and pain in hands and feet), porphyria, haemodialysis, diabetes, gout (high uric acid), liver toxicity, dialysis, optic neuritis (vision problems), kidney or liver dysfunction.

• ERYTHROMYCIN
• ACETAMINOPHEN
• INSULIN ISOPHANE
• SAQUINAVIR
• RITONAVIR
• ERGOCALCIFEROL

• Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
• Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
• Avoid processed and fried foods.
• Warm ginger tea or warm soup can help relieve cough.
• Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
• Quit smoking and avoid alcohol consumption.

• Macox-ZH Tablet may affect the results of some blood tests, such as those for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking Macox-ZH Tablet.
• Your doctor may advise you to get regular liver tests while taking Macox-ZH Tablet to check how your liver is functioning.

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through tiny droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.