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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Macflox Infusion is an antibiotic medicine used in the treatment of bacterial infections such as lung infections, infections of the airways, infections of the sinuses, skin and skin structure infections, and complicated intra-abdominal infections. This medicine contains moxifloxacin which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include nausea, vomiting, stomach pain, loss of appetite, dizziness, and headache.
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Whats That

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Composition :

MOXIFLOXACIN-400MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Macflox Infusion

Macflox Infusion belongs to the class of 'fluoroquinolone antibiotics', primarily used to treat bacterial infections such as lung infections, infections of the airways, infections of the sinuses, skin and skin structure infections, and complicated intra-abdominal infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiply very quickly.

Macflox Infusion contains Moxifloxacin, which acts as a bactericidal agent that kills the infection-causing bacteria. It works by stopping the bacteria's ability to copy their genetic material (DNA), this prevents the bacteria from replicating, thereby kills the bacteria and treats bacterial infections.

Macflox Infusion will be administered by a healthcare professional. In some cases, you may experience common side effects like nausea, vomiting, stomach pain, loss of appetite, dizziness, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is not advisable to stop this medicine suddenly to avoid unpleasant side effects. Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), difficulty in sleeping or sleeping disorder (sleep apnoea), severe liver disease, or problem with alcohol or other recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant or breastfeeding. Macflox Infusion may cause dizziness affecting your ability to drive; hence, drive only when you are alert.

Uses of Macflox Infusion

Treatment of Bacterial infections

Directions for Use

Injection/Infusion: It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Macflox Infusion belongs to the class of 'fluoroquinolone antibiotics', primarily used to treat bacterial infections such as lung infections, infections of the airways, infections of the sinuses, skin and skin structure infections, and complicated intra-abdominal infections. Macflox Infusion works by stopping the bacteria's ability to copy their genetic material (DNA), this prevents the bacteria from replicating, thereby kills the bacteria and treats bacterial infections. It is a broad-spectrum antibiotic effective against a wide range of gram-positive, gram-negative, and anaerobic bacteria (that live without oxygen).

How Macflox Infusion Works

Macflox Infusion contains Moxifloxacin, which acts as a bactericidal agent that kills the infection-causing bacteria. It works by stopping the bacteria's ability to copy their genetic material (DNA), this prevents the bacteria from replicating, thereby kills the bacteria and treats bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Macflox Infusion

  • Nausea
  • Vomiting
  • Stomach pain
  • Loss of appetite
  • Dizziness
  • Headache

What if I have taken an overdose of Macflox Infusion

A healthcare professional administers Macflox Infusion in a hospital setting. Hence, the chances of overdose are less. Overdose symptoms can include seizures, trembling, lightheadedness, dizziness, and persistent headaches (with or without blurry vision); sleep difficulties, nightmares, and a lack of trust in other people. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Macflox Infusion if you are allergic to any of its components. Let your doctor know if you have tendon/bone problems, heart problems, high blood pressure, diabetes, epilepsy, myasthenia gravis, liver or kidney diseases before starting Macflox Infusion. Macflox Infusion is not recommended during pregnancy and breastfeeding. Macflox Infusion may cause dizziness affecting your ability to drive; hence, drive only when you are alert. Avoid alcohol consumption since it may lead to increased dizziness. Macflox Infusion is not recommended for children and adolescents under the age of 18.

Drug-Drug Interactions

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MoxifloxacinQuinidine
Critical
MoxifloxacinBepridil
Critical

Drug-Drug Interactions

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MoxifloxacinQuinidine
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using quinidine together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Quinidine can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
MoxifloxacinBepridil
Critical
How does the drug interact with Macflox Infusion 10 ml:
Coadministration of Macflox Infusion 10 ml with Bepridil may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Bepridil is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
MoxifloxacinProcainamide
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using procainamide together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Procainamide can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
MoxifloxacinAmiodarone
Critical
How does the drug interact with Macflox Infusion 10 ml:
Taking Amiodarone and Macflox Infusion 10 ml may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone and Macflox Infusion 10 ml is not recommended as it can lead to an interaction; it can be taken if advised by a doctor. If you get dizziness, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
MoxifloxacinDronedarone
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using dronedarone together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Dronedarone is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
MoxifloxacinHalofantrine
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using Halofantrine together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Halofantrine is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
MoxifloxacinSotalol
Critical
How does the drug interact with Macflox Infusion 10 ml:
Combining Macflox Infusion 10 ml with Sotalol can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sotalol with Macflox Infusion 10 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MoxifloxacinSaquinavir
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using saquinavir together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Saquinavir can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
MoxifloxacinDisopyramide
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using Disopyramide together with Macflox Infusion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Disopyramide is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting your doctor.
MoxifloxacinZiprasidone
Critical
How does the drug interact with Macflox Infusion 10 ml:
Using Macflox Infusion 10 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Macflox Infusion 10 ml with Ziprasidone is not recommended as it can lead to an interaction; it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after completing the full course of Macflox Infusion in order to restore the healthy bacteria in the intestines that may have been killed due to antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the good bacteria of the intestine. 
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Macflox Infusion. 
  • Avoid intake of alcoholic beverages with Macflox Infusion as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Macflox Infusion in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Macflox Infusion Substitute

Substitutes safety advice
  • Moxicip Tablet 10's

    26.01per tablet
  • Moxif 400 Tablet 5's

    26.02per tablet
  • Moxiflox Tablet 5's

    26.02per tablet
  • Mahaflox-400 Tablet 5's

    21.96per tablet
  • M-Cin Tablet 5's

    26.02per tablet
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Alcohol

Caution

It is not known how Macflox Infusion is affected by alcohol consumption; please consult your doctor for more information.

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Pregnancy

Unsafe

Macflox Infusion is not recommended during pregnancy. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before starting Macflox Infusion.

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Breast Feeding

Unsafe

Macflox Infusion is not recommended during breastfeeding. If you are a breastfeeding mother, please seek medical advice before starting Macflox Infusion.

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Driving

Caution

Macflox Infusion may make you feel dizzy or light-headed. If you experience any of these, do not drive or operate machinery.

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Liver

Caution

Macflox Infusion is to be taken with caution if you have a history of liver diseases/conditions.

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Kidney

Caution

Macflox Infusion is to be taken with caution if you have a history of kidney diseases/conditions.

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Children

Unsafe

Macflox Infusion is not recommended for children and adolescents under the age of 18 because efficacy and safety have not been established for this age group.

FAQs

Macflox Infusion belongs to the class of fluoroquinolone antibiotics primarily used to treat bacterial infections such as lung infections, infections of the airways, infections of the sinuses, skin and skin structure infections, and complicated intra-abdominal infections.
Macflox Infusion works by stopping the bacteria's ability to copy their genetic material (DNA), this prevents the bacteria from replicating, thereby kills the bacteria and treats bacterial infections.
Macflox Infusion may make the skin sensitive to sunlight. So, prolonged exposure to strong sunlight/UV light should be avoided while using Macflox Infusion. Wear protective clothing, sunglasses, and sunscreen while going out.
Macflox Infusion may cause muscle weakness and should be avoided in people who have muscle weakness or myasthenia gravis as it might worsen the condition. Please consult your doctor, before starting Macflox Infusion if you have any such disease condition.
Macflox Infusion is an antibacterial medicine that acts only against bacterial infections and not viral infections like cough, cold and flu.
It is recommended to complete the course even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Macflox Infusion for as long as your doctor has prescribed to treat your condition effectually.

Country of origin

INDIA

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - MAC0338

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