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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mac Rabonik Plus Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. It contains Rabeprazole and Levosulpiride which work by blocking acid production and preventing the backflow of food and acid into the mouth. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Eris Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mac Rabonik Plus Capsule

Mac Rabonik Plus Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Mac Rabonik Plus Capsule is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Mac Rabonik Plus Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Mac Rabonik Plus Capsule may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Mac Rabonik Plus Capsule may cause drowsiness and dizziness, so drive only if you are alert. Mac Rabonik Plus Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Mac Rabonik Plus Capsule as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Mac Rabonik Plus Capsule

Treatment of Gastro-oesophageal reflux disease, acidity, indigestion, heartburn, and peptic ulcers.

Directions for Use

Take Mac Rabonik Plus Capsule 1 hour prior to food. Swallow Mac Rabonik Plus Capsule as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Mac Rabonik Plus Capsule is a combination of two drugs: Rabeprazole and Levosulpiride. Mac Rabonik Plus Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

How Mac Rabonik Plus Capsule Works

Mac Rabonik Plus Capsule is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mac Rabonik Plus Capsule

  • Headache
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Dizziness
  • Diarrhoea 

What if I have taken an overdose of Mac Rabonik Plus Capsule

Take Mac Rabonik Plus Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Mac Rabonik Plus Capsule if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Mac Rabonik Plus Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Mac Rabonik Plus Capsule may cause dizziness and drowsiness, so drive only if you are alert. Mac Rabonik Plus Capsule is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Mac Rabonik Plus Capsule 10's:
When used in combination with erlotinib, Mac Rabonik Plus Capsule 10's may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Mac Rabonik Plus Capsule 10's with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Co-administration of Mac Rabonik Plus Capsule 10's can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Mac Rabonik Plus Capsule 10's with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Ritonavir can increase the blood levels of Mac Rabonik Plus Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Mac Rabonik Plus Capsule 10's and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Combining Mizolastine with Mac Rabonik Plus Capsule 10's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Mac Rabonik Plus Capsule 10's and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Mac Rabonik Plus Capsule 10's:
Coadministration of Mac Rabonik Plus Capsule 10's with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Mac Rabonik Plus Capsule 10's and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating to prevent acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practice relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS, ANTIULCERANTS

Mac Rabonik Plus Capsule Substitute

Substitutes safety advice
  • Neopride Total 40 Tablet 10's

    by AYUR

    33.75per tablet
  • Rablet L 40 Capsule 10's

    by AYUR

    33.12per tablet
  • Rabonik 40 Plus Capsule 10's

    28.13per tablet
  • REKOOL L 40MG TABLET

    33.93per tablet
  • TWICHEK PLUS CAPSULE

    9.54per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mac Rabonik Plus Capsule . Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

bannner image

Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Mac Rabonik Plus Capsule may pass into breast milk. Consult your doctor if you are breastfeeding; your doctor will decide whether Mac Rabonik Plus Capsule can be taken by breastfeeding mothers or not.

bannner image

Driving

Caution

Mac Rabonik Plus Capsule may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Mac Rabonik Plus Capsule should not be given to children as the safety and effectiveness were not established.

FAQs

Mac Rabonik Plus Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers.
Mac Rabonik Plus Capsule contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents the backflow of food and acid into the mouth. Together, Mac Rabonik Plus Capsule helps in providing relief from acidity.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Mac Rabonik Plus Capsule contains rabeprazole which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of Mac Rabonik Plus Capsule for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.
Dry mouth could be a side-effect of Mac Rabonik Plus Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.
Do not take Mac Rabonik Plus Capsule for longer durations unless prescribed by the doctor. Mac Rabonik Plus Capsule might cause bone problems and hypomagnesemia on long-term treatment. Talk to your doctor if you do not find symptomatic relief despite taking Mac Rabonik Plus Capsule for 2 weeks.
Mac Rabonik Plus Capsule might cause irregular periods/abnormal menstruation. Consult your doctor if you notice abnormal bleeding patterns.
Avoid consuming alcohol along with Mac Rabonik Plus Capsule as it could lead to increased drowsiness and elevate stomach acid production.
If you're experiencing frequent heartburn and stomach pain while taking Mac Rabonik Plus Capsule , it's essential to consult with your doctor. They can assess your specific situation and provide the best course of action.
Mac Rabonik Plus Capsule is typically used to treat excessive stomach acid production conditions. It's essential to consult with a healthcare professional to determine if Mac Rabonik Plus Capsule is appropriate for your specific condition. They can assess your symptoms, medical history, and other factors to provide personalized guidance.
The best time to take Mac Rabonik Plus Capsule depends on your doctor's specific instructions. However, a common recommendation is to take it before breakfast. This helps the medication effectively reduce stomach acid production throughout the day.
Mac Rabonik Plus Capsule is more often used to treat gastrointestinal disorders. However, its use may be contraindicated in individuals with allergies to either the drug or its excipients, pregnant or breastfeeding women, those with gastrointestinal bleeding or obstruction, severe kidney or liver impairment, and individuals with certain medical conditions. Before using Mac Rabonik Plus Capsule , it's essential to consult with a healthcare professional to assess your individual situation and determine if it's safe for you.
Mac Rabonik Plus Capsule combines two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent).
The safety of Mac Rabonik Plus Capsule during pregnancy and breastfeeding has not been fully established. If you are pregnant or breastfeeding, it's essential to discuss the risks and benefits of taking Mac Rabonik Plus Capsule with your doctor.
Yes, dizziness can be a side effect of taking Mac Rabonik Plus Capsule .
No definitive evidence suggests that using Mac Rabonik Plus Capsule increases the risk of fractures. If you have concerns about your risk of fractures, it's best to discuss them with your doctor. They can assess your individual situation and provide appropriate advice.
Mac Rabonik Plus Capsule may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.
It's always best to follow the specific storage and disposal instructions provided on the medication packaging or by your pharmacist. If you have any questions or concerns, don't hesitate to ask your healthcare provider.
Common side effects of Mac Rabonik Plus Capsule may include headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Country of origin

India

Manufacturer/Marketer address

8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India
Other Info - MAC0283

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